2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5 Tolvaptan Intermediate Factory Zoo
Chaw tsim khoom, siab zoo, kev lag luam ntau lawm
Tolvaptan thiab lwm tus neeg nruab nrab:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
Tom ntej: 4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
Tom ntej: 2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
| Tshuaj npe | 2-Methyl-4-Nitrobenzoic Acid |
| Synonyms | 4-Nitro-o-Toluic acid;4-Nitro-2-Methylbenzoic Acid |
| CAS Nr | Xyoo 1975-51-5 |
| CAT Number | Qauv: RF-PI397 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
| Molecular Formula | C8H7 NPO 4 |
| Molecular Luj | 181.15 Nws |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Yuav luag Dawb los yog daj daj daj Crystal hmoov |
| 1 H-NMR | Raws li tus qauv |
| Purity / Analysis Method | ≥98.0% (HPLC) |
| Melting Point | 153.0 ~ 156.0 ℃ |
| Moisture (KF) | ≤0.50% |
| Residue ntawm Ignition | ≤0.50% |
| Tag nrho cov impurities | ≤ 2.0% |
| Test Standard | Enterprise Standard |
| Kev siv | Tus neeg nruab nrab ntawm Tolvaptan (CAS 150683-30-0) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo.
2-Methyl-4-Nitrobenzoic Acid (CAS 1975-51-5) yog siv los ua tshuaj nruab nrab hauv kev sib txuas ntawm Tolvaptan (CAS 150683-30-0).Tolvaptan yog ib qho kev xaiv, kev sib tw arginine vasopressin receptor 2 antagonist nrog IC50 ntawm 1.28μM rau inhibition ntawm AVP-induced platelet aggregation.Tolvaptan yog siv los kho hyponatremia (cov ntshav sodium tsawg) cuam tshuam nrog lub plawv tsis ua haujlwm, cirrhosis, thiab cov tsos mob ntawm cov tshuaj tsis tsim nyog antidiuretic hormone (SIADH).Tolvaptan tau pom zoo los ntawm US Food and Drug Administration thaum lub Tsib Hlis 19, 2009, thiab muag los ntawm Otsuka Pharmaceutical Co. nyob rau hauv lub npe lag luam Samsca.
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