2,3-Dihydrobenzofuran CAS 496-16-2 Ramelteon Intermediate Purity > 99.0% (GC)
Cov Chaw Tsim Khoom Ua Lag Luam thiab Chaw Muag Khoom, Intermediates ntawm Ramelteon
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-one CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
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| Tshuaj npe | 2,3-Dihydrobenzofuran hmoov |
| Synonyms | Coumaran;2,3-Dihydro-2,3-Benzofuran;2,3-Dihydrobenzo[b]furan;2,3-Dihydro-1-Benzofuran 2 |
| CAS Nr | 496-16-2 : kuv |
| CAT Number | TIAB SA 2884 |
| Tshuag xwm txheej | Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 20 Tons ib Hlis |
| Molecular Formula | c8h8 ua |
| Molecular Luj | 120.15 Nws |
| Melting Point | -21 ℃ |
| Boiling Point | 188.0 ~ 189.0 ℃ (lit.) |
| Flash Point | 66 ℃ |
| Solubility | Cawv: Soluble |
| Kev Ceeb Toom | Irritant |
| TSCA | Yog lawm |
| HS Code | 293299 5 |
| Cia Temp. | Muab ntim rau hauv Qhuav, Chav Kub Kub |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Clear Colorless los yog Yellowish kua |
| Purity / Analysis Method | > 99.0% (GC) |
| Dej (los ntawm Karl Fischer) | <0.50% |
| Qhov ceev (20 ℃) | 1.065-1.085 Nws |
| Refractive Index n20/D | 1.547-1.551 Nws |
| Ib leeg Impurity | <0.50% |
| Tag nrho cov impurities | <1.00% |
| Proton NMR Spectrum | Raws li tus qauv |
| Test Standard | Enterprise Standard |
| Kev siv | Pharmaceutical Intermediate ntawm Ramelteon (CAS: 196597-26-9) |
Pob: Fluorinated Fwj, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
2,3-Dihydrobenzofuran (CAS: 496-16-2) yog dav siv nyob rau hauv lub synthesis ntawm tricyclic compounds thiab kuj yog ib tug nruab nrab raw khoom rau cov synthesis ntawm ib co tseem ceeb tshuaj.2,3-Dihydrobenzofuran tuaj yeem siv los ua tus nruab nrab ntawm Ramelteon (CAS: 196597-26-9).Ramelteon, ua lag luam raws li Rozerem los ntawm Takeda Pharmaceuticals North America, yog tus neeg sawv cev pw tsaug zog uas xaiv khi rau MT1 thiab MT2 receptors hauv suprachiasmatic nucleus (SCN), es tsis txhob khi rau GABAA receptors, xws li nrog tshuaj xws li zolpidem.Txawm li cas los xij nws tsis tshwm sim ua kom qhov pib ntawm kev pw tsaug zog lossis pw tsaug zog ntau npaum li cas tus neeg tau txais.Nws tau pom zoo los ntawm US Food and Drug Administration (FDA) rau kev siv mus sij hawm ntev.Ramelteon tsis pom muaj kev cuam tshuam zoo rau GABAA receptors, uas cuam tshuam nrog anxiolytic, myorelaxant, thiab amnesic teebmeem.Tsis zoo li feem ntau cov kev kho mob ntawm insomnia uas tsom rau GABA (g-aminobutyric acid) receptor complex, ramelteon yog ib qho agonist ntawm melatonin receptor.Tshwj xeeb, nws muaj kev xaiv siab rau MT1 thiab MT2 subtypes, uas tau cuam tshuam rau kev saib xyuas ntawm circadian rhythms, dhau ntawm MT3 receptor lub luag haujlwm rau lwm yam melatonin zog.2,3-Dihydrobenzofuran kuj tseem siv rau hauv kev sib txuas ntawm cov tshuaj tua kab mob benzofuran sulfonylureas, HIV protease inhibitor amino acid hydroxyethylenesulfonyl, matrix metalloproteinase inhibitor aryl sulfinyl isoxime hydroxamic acid, thiab lwm yam.
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