2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5 Remdesivir Intermediate COVID-19
Chaw tsim tshuaj paus kev lag luam muab Remdesivir thiab cuam tshuam nrog cov khoom zoo
Remdesivir CAS 1809249-37-3
2-Ethyl-1-butanol CAS 97-95-0
Tom ntej: Trimethylsilyl Cyanide CAS 7677-24-9
4-Nitrophenol CAS 100-02-7
2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS 1911578-98-7
N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester CAS 1354823-36-1
(S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3
Remdesivir Metabolite (GS-441524) CAS 1191237-69-0
Remdesivir N-2 Intermediate CAS 1191237-80-5
Tom ntej: 2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5
7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5
Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8
4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS 1770840-43-1
Tshuaj npe | 2,3,5-Tri-O-benzyl-D-ribonolactone |
Synonyms | 2,3,5-Tri-O-Benzyl-D-Ribono-1,4-Lactone;Remdesivir Intermediate |
CAS Nr | 55094-52-5 |
CAT Number | Qauv TSIS MUAJ: RF-PI301 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms |
Molecular Formula | C26H26O5 |
Molecular Luj | 418.49 ib |
Melting Point | 54.0-55.0 ℃ |
Kev cia khoom | Chav ntsuas kub |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Yellowish lossis Dawb Khoom |
Solubility | Soluble hauv CH2Cl2 thiab Insoluble hauv H2O |
NMR thiab MS | Yuav tsum ua raws |
Kev txheeb xyuas | IR thiab TLC |
Moisture | ≤ 1.0% |
Residue ntawm Ignition | ≤0.50% |
Txhua tus neeg impurity | ≤0.50% |
Hnyav Hlau | ≤ 50ppm |
HPLC (210nm) | ≥99.0% |
HPLC (ELSD) | ≥99.0% |
Test Standard | Enterprise Standard |
Kev siv | Intermediate of Remdesivir (CAS 1809249-37-3) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
2,3,5-Tri-O-benzyl-D-ribonolactone (CAS 55094-52-5) yog Remdesivir intermediate.Remdesivir (CAS 1809249-37-3) yog cov tshuaj tiv thaiv kab mob tshiab hauv chav kawm ntawm nucleotide analogs, siv los kho COVID-19.Remdesivir (GS-5734) yog ib qho tshuaj tiv thaiv kab mob nucleoside tshiab uas inhibits murine hepatitis virus (MHV) nrog EC50 zoo ib yam li SARS-CoV thiab MERS-CoV.Coronaviruses (CoVs) yog qhov muaj txiaj ntsig zoo, ib leeg-stranded RNA cov kab mob uas kis tau rau ntau hom tsiaj.Hauv tib neeg, CoVs tau lees paub tias feem ntau ua rau mob khaub thuas thiab mob ntsws kom txog thaum muaj mob hnyav ua pa nyuaj ua pa mob coronavirus (SARS-CoV) hauv xyoo 2002 thiab Middle East respiratory syndrome coronavirus (MERS-CoV) hauv 2012 los ntawm zoonotic qhov chaw.Remdesivir yog monophosphoramidate prodrug ntawm C-adenosine nucleoside analogue GS-441524.Nyob rau hauv qeeb hlwb qog (DBT) hlwb kis MHV, GS-5734 inhibited MHV muaj zog tshaj GS-441524, nrog ib tug GS-5734 EC50 ntawm 0.03 M. Tsis tas li ntawd, EC50 qhov tseem ceeb tau txiav txim siab tom qab kho nrog GS-441524 thiab GS-573. in SARS-CoV- and MERS-CoV-infected primary human airway epithelial cell (HAE) cultures.