2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0 Purity ≥99.5% (GC) Sitagliptin Phosphate Monohydrate Intermediate
Muab Sitagliptin Phosphate Monohydrate Related Intermediates:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
Tom ntej: 2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3
Tshuaj npe | 2,4,5-Trifluorophenylacetic Acid |
CAS Nr | 209995-38-0 |
CAT Number | Qauv: RF-PI1191 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C8H5F3O2 |
Molecular Luj | 190.12 Nws |
Melting Point | 121.0 txog 125.0 ℃ |
Solubility | Soluble hauv Methanol |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Off-White Powder |
Purity / Analysis Method | ≥99.5% (GC) |
Moisture (KF) | ≤0.50% |
Residue ntawm Igniton | ≤0.50% |
Tag nrho cov impurities | ≤0.50% |
Test Standard | Enterprise Standard |
Kev siv | Intermediate ntawm Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo.
2,4,5-Trifluorophenylacetic Acid (CAS: 209995-38-0) yog ib qho nruab nrab ntawm Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9).Sitagliptin Phosphate (STG) yog siv los kho DM hom 2 vim nws txhim kho glycemic tswj los ntawm kev nce qib ntawm cov tshuaj hormones nquag incretin, GLP-1 (peptide-1) thiab GIP (glucose-dependent insulinotropic peptide).Kev ua kom cov incretins nyob rau hauv β-pancreatic hlwb ua rau nce qib ntawm cyclic adenosine monophosphate (cAMP) thiab intracellular calcium, nrog rau cov piam thaj-dependent insulin secretion (2).Cov tshuaj hypoglycemic no yog nyob rau hauv chav kawm tshiab hu ua dipeptidyl peptidase IV inhibitors.STG tau pom zoo los ntawm FDA hauv xyoo 2006.