3-Ethynylaniline CAS 54060-30-9 Purity > 99.0% (GC) Erlotinib Hydrochloride Intermediate
Ua cov chaw tsim khoom thiab cov chaw muag khoom ntawm Erlotinib Hydrochloride Intermediates
Erlotinib Hydrochloride CAS 183319-69-9
3-Ethylaniline CAS 54060-30-9
6,7-Bis (2-Methoxyethoxy) -3H-Quinazolin-4-one CAS 179688-29-0
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Tshuaj npe | 3- Ethynylaniline |
Synonyms | 3-Aminophenylacetylene |
CAS Nr | 54060-30-9 |
CAT Number | Qauv TSIS MUAJ: RF-PI2241 |
Tshuag xwm txheej | Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 50MT / Lub Hlis |
Molecular Formula | C8H7 N |
Molecular Luj | 117.15 Nws |
rhiab heev | Cua Sensitive, Lub teeb Sensitive |
Boiling Point | 120 ℃ / 20 mmHg |
Dej Solubility | Insoluble hauv dej |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Lub teeb daj rau xim av kua |
Purity / Analysis Method | > 99.0% (GC) |
Dej los ntawm Karl Fischer | <0.50% |
Residue ntawm Ignition | <0.20% |
Tag nrho cov impurities | <1.00% |
Lub ntiajteb txawj nqus (20/20 ℃) | 1.041-1.048 Nws |
Refractive Index n20/D | 1.614-1.6195 Ib |
Infrared Spectrum | Raws li tus qauv |
Proton NMR Spectrum | Raws li tus qauv |
Test Standard | Enterprise Standard |
Kev siv | Pharmaceutical Intermediate;Erlotinib Hydrochloride Intermediate |
Pob: Fluorinated Fwj, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
3-Ethynylaniline, tseem hu ua 3-Aminophenylacetylene (CAS: 54060-30-9) yog siv los ua tshuaj nruab nrab.3-Ethynylaniline yog ib qho nruab nrab ntawm Erlotinib Hydrochloride (CAS: 183319-69-9).Erlotinib Hydrochloride yog ib tug me me molecule tyrosine kinase inhibitor uas ua reversibly ntawm epidermal loj hlob receptors, ib tug hydrochloride ntawm erlotinib, ib tug molecular-targeted tshuaj.US Food and Drug Administration (FDA) tau pom zoo erlotinib (Tarceva) ua ke nrog gemcitabine raws li kev kho thawj zaug rau kev mob qog noj ntshav hauv zos thiab metastatic pancreatic.Nws yog siv los ua kev kho mob thib ob lossis thib peb rau kev kho mob hauv zos lossis kab mob metastatic uas tsis yog-me me ntawm lub ntsws cancer (NSCLC) thiab ua kev kho mob rau pancreatic cancer.Nws yog siv los ua tyrosine inhibitor rau kev kho NSCLC.Erlotinib Hydrochloride, ib qho quinazoline muab tau los ntawm me me molecule inhibitor ntawm epidermal kev loj hlob receptor (EDGFR) tyrosine kinase, tau pom zoo nyob rau lub Kaum Ib Hlis, 2004, rau kev kho mob ntawm cov mob cancer siab heev los yog metastatic non-smallcell ntsws cancer.