3-Nitrophthalic Anhydride CAS 641-70-3 Pomalidomide Intermediate Purity > 98.0% (HPLC)
Ruifu Chemical yog cov chaw tsim khoom ntawm 3-Nitrophthalic Anhydride (CAS: 641-70-3) nrog cov khoom zoo, nruab nrab ntawm Pomalidomide (CAS: 19171-19-8).Ruifu Chemical tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, kev pabcuam zoo heev, me me thiab ntau ntau muaj.Yuav 3-Nitrophthalic Anhydride,Please contact: alvin@ruifuchem.com
| Tshuaj npe | 3-Nitrophthalic Anhydride |
| Synonyms | 3-Nitrophthalic Acid Anhydride;4-Nitro-2-Benzofuran-1,3-Dione;4-Nitroisobenzofuran-1,3-Dione;4-Nitro-1,3-isobenzofurandione;Pomalidomide impurity A |
| Tshuag xwm txheej | Hauv Tshuag, Kev Lag Luam Ntau Lawm |
| CAS Nr | 641-70-3 : kuv |
| Molecular Formula | C8H3NO5 |
| Molecular Luj | 193.11 g / mol |
| Melting Point | 161.0 txog 165.0 ℃ |
| rhiab heev | Moisture Sensitive |
| Dej Solubility | Yuav Decompose hauv dej |
| COA & MSDS | Muaj |
| Keeb kwm | Shanghai, Suav |
| Hom | Ruifu Tshuaj |
| Cov khoom | Kev soj ntsuam Standards | Cov txiaj ntsig |
| Qhov tshwm sim | Lub teeb daj rau daj koob Crystal lossis Crystalline hmoov | Ua raws |
| Melting Point | 161.0 ~ 165.0 ℃ | 163.0 ~ 165.0 ℃ |
| Poob rau ziab | <0.50% | 0.10% |
| Purity / Analysis Method | > 98.0% (HPLC) | 98.85% |
| Infrared Spectrum | Raws li tus qauv | Ua raws |
| 1 H NMR Spectrum | Raws li tus qauv | Ua raws |
| Xaus | Cov khoom tau raug kuaj thiab ua raws li cov lus qhia tshwj xeeb | |
| Daim ntawv thov | Intermediate ntawm Pomalidomide (CAS: 19171-19-8) | |
Pob:Fluorinated Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, lossis raws li cov neeg siv khoom xav tau.
Cia txias:Huab cua rhiab heev.Khaws lub thawv kaw kom nruj thiab khaws cia rau hauv qhov chaw txias, qhuav thiab zoo-ventilated warehouse kom deb ntawm cov khoom tsis sib xws.Cia kom deb ntawm tshav ntuj;zam hluav taws;tsis txhob ya raws.Khaws kom deb ntawm oxidizing tus neeg sawv cev.
Shipping:Xa mus thoob ntiaj teb los ntawm huab cua, los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
Hazard Symbols Xi - Irritant
Risk Codes
36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij.
Kev nyab xeeb piav qhia
S26 - Nyob rau hauv rooj plaub ntawm qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
S36 - Hnav khaub ncaws tiv thaiv zoo.
S37/39 - Hnav cov hnab looj tes tsim nyog thiab tiv thaiv qhov muag / ntsej muag
WGK Germany 3
FLUKA BRAND F CODE 10-21
TSCA Yes
HS Code 2917399090
3-Nitrophthalic Anhydride (CAS: 641-70-3) yog siv los ua ib qho nruab nrab ntawm Pomalidomide (CAS: 19171-19-8).Thaum Lub Ob Hlis 2013, US FDA tau pom zoo Pomalidomide rau kev kho mob ntau yam myeloma (MM) hauv cov neeg mob uas muaj kab mob tshwm sim tom qab tau txais lwm yam kev kho mob qog noj ntshav.Pomalidomide yog 4-amino analog ntawm thalidomide nrog kev txhim kho potency thiab txhim kho toxicity profile.Pomalidomide thiab thalidomide siv lawv cov teebmeem los ntawm kev hloov kho kev tiv thaiv, inhibition ntawm angiogenesis, cuam tshuam nrog cov pob txha / qog microenvironment, thiab inhibition ntawm cereblon protein.Pomalidomide muaj zog inhibited nyob rau hauv vitro proliferation nyob rau hauv ntau yam ntawm tib neeg MM cell kab, IC50 ~ 10 nM, thaum thalidomide pom yuav luag tsis muaj inhibition txog li 100 μM.Hauv cov qauv nas MM qog, 50 mg / kg txhua hnub koob tshuaj ntawm pomalidomide ua rau muaj kev cuam tshuam ntawm cov qog loj hlob tom qab 15 hnub ntawm kev kho mob thiab ua tiav regression hauv 3-6 lub lis piam piv rau thalidomide-kho tswj ntawm tib koob.Pomalidomide yog npaj los ntawm condensation ntawm 3-Nitrophthalic Anhydride nrog 3-Aminopiperidine-2,6-Dione ua raws li catalytic hydrogenation ntawm pawg nitro.
