4-[(1-Pyrrolidinylsulfonyl)methyl]aniline CAS 334981-10-1 Purity > 99.0% (HPLC) Almotriptan Aniline Precursor Factory
Ruifu Chemical Supply Almotriptan Malate Intermediates:
Almotriptan Malate CAS 181183-52-8
1-((4-Hydrazinylbenzyl)sulfonyl)pyrrolidine Hydrochloride CAS 334981-11-2
4-[(1-Pyrrolidinylsulfonyl)methyl]aniline CAS 334981-10-1
1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine CAS 340041-91-0
4-Chlorobutyraldehyde Diethyl Acetal CAS 6139-83-9
Tshuaj npe | 4-[(1-Pyrrolidinylsulfonyl)methyl]aniline |
Synonyms | 1-[(4-Aminobenzyl)sulfonyl]pyrrolidine;Almotriptan Aniline Precursor |
CAS Nr | 334981-10-1 |
CAT Number | RF-PI 1948 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C11H16N2O2S |
Molecular Luj | 240.32 Nws |
Melting Point | 170.0 txog 176.0 ℃ |
Qhov ntom | 1.31 ib |
Solubility | Me ntsis Soluble hauv Toluene |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Faint Yellow Crystalline Hmoov |
Purity / Analysis Method | > 99.0% (HPLC) |
Poob rau ziab | <0.50% |
Residue ntawm Ignition | <0.50% |
Max ib leeg impurity | <0.50% |
Tag nrho cov impurities | <1.00% |
Hnyav Hlau | <20 ppm |
Infrared Spectrum | Raws li tus qauv |
NMR | Raws li tus qauv |
Test Standard | Enterprise Standard |
Kev siv | Almotriptan Aniline Precursor |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
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4-[(1-Pyrrolidinylsulfonyl)methyl]aniline (CAS: 334981-10-1) yog ib qho nruab nrab hauv kev npaj ntawm Almotriptan Malate (CAS: 181183-52-8), Almotriptan Aniline Precursor.Almotriptan Malate yog ib hom tshuaj triptan uas tuaj yeem siv rau kev kho mob taub hau migraine.Almotriptan yog nyob rau hauv ib pawg tshuaj ntawm kev xaiv serotonin receptor agonists.Almotriptan muaj qhov tshwj xeeb thiab tshwj xeeb affinity rau serotonin 5-HT receptors, ntxiv rau vascoconstriction ntawm lub hlwb hlab ntsha thiab cuam tshuam rau redistribution ntawm cov ntshav khiav.Cov teebmeem no txwv tsis pub cov tsos mob ntawm kev xa mus rau lub hlwb, thiab ntxiv rau kev tso tawm ntawm qee yam tshuaj uas ua rau mob, xeev siab thiab lwm yam mob migraine.Txawm li cas los xij, Almotriptan tsis tiv thaiv migraine tawm tsam.Almotriptan, ua lag luam nyob rau hauv 2000, muaj lub siab tshaj plaws oralbioavailability ntawm tag nrho cov triptans.Almotriptan yog metabolized los ntawm ob qho tib si MAO-A thiab CYP3A4, yog li muaj cov txiaj ntsig zoo dua qub thaum piv nrog Sumatriptan.