4-Chlorobenzo[b]thiophene CAS 66490-33-3 Purity > 98.0% (GC) Brexpiprazole Intermediate Factory
Ruifu Chemical Supply Brexpiprazole Intermediates
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4-Chlorobenzo [b]thiophene CAS 66490-33-3
Tshuaj npe | 4-Chlorobenzo [b]thiophene |
Synonyms | 4-Chloro-Benzo[b]thiophene;4-Chloro-1-Benzothiophene;4-Chlorobenzothiophene |
CAS Nr | 66490-33-3 |
CAT Number | RF-PI 1983 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C8H5Cls |
Molecular Luj | 168.64 ib |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Xim tsis muaj kua |
Purity / Analysis Method | > 98.0% (GC) |
Tag nrho cov impurities | <2.00% |
Infrared Spectrum | Raws li tus qauv |
NMR | Raws li tus qauv |
Test Standard | Enterprise Standard |
Kev siv | Intermediate ntawm Brexpiprazole (CAS: 913611-97-9) |
Pob: Fluorinated Fwj, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
4-Chlorobenzo[b]thiophene (CAS: 66490-33-3) is an Intermediate of Brexpiprazole (CAS: 913611-97-9).Brexpiprazole yog ib qho tshuaj tiv thaiv kev puas siab puas ntsws tshiab uas ua haujlwm ua serotonin ® dopamine kev ua haujlwm modulator thiab tau pom tias muaj txiaj ntsig zoo li kev kho mob ntxiv rau cov neeg mob uas muaj kev nyuaj siab loj (MDD).Cov tshuaj muaj ib tug tshwj xeeb pharmacological profile, ua raws li ib feem agonist ntawm serotonin 5-HT1A thiab dopamine D2 receptors thiab raws li ib tug tag nrho antagonist ntawm 5-HT2A thiab noradrenaline α1B / 2C receptors, nrog zoo sib xws subnanomolar binding affinity.Cov tshuaj, uas yog tsim los ntawm Otsuka thiab Lundbeck, tau pom zoo nyob rau hauv 2015 los ntawm FDA rau kev kho mob ntawm schizophrenia thiab raws li ib tug adjunctive kev kho mob rau kev nyuaj siab.Brexpiprazole yog dav suav hais tias yog ib tug successor rau Otsuka cov tshuaj antipsychotic aripiprazole (lub npe lag luam Abilify) uas nws patent tas rau lub yim hli ntuj 2014.