4-Dimethylaminopyridine DMAP CAS 1122-58-3 Purity > 99.0% (HPLC) Kev Ua Haujlwm Zoo Tshaj Plaws
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom ntawm 4-Dimethylaminopyridine (DMAP) (CAS: 1122-58-3) nrog cov khoom zoo.Ruifu Chemical tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, me me thiab ntau ntau muaj.Yuav DMAP, Please contact: alvin@ruifuchem.com
Tshuaj npe | 4-Dimethylaminopyridine |
Synonyms | DMAP;4- (Dimethylamino) pyridine;N-(4-Pyridyl) dimethylamine;N, N-Dimethylpyridin-4-Amine;N, N-Dimethyl-4-Pyridinamine;gamma-(Dimethylamino) pyridine |
CAS Nr | 1122-58-3 |
Tshuag xwm txheej | Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 40 Tons ib Hlis |
Molecular Formula | C7H10N2 |
Molecular Luj | 122.17 Nws |
Melting Point | 110.0 ~ 114.0 ℃ |
Boiling Point | 190 ℃ / 150 mmHg |
Qhov ntom | 0.906 g / mL ntawm 25 ℃ |
Refractive Index | N20/D 1.431 |
Solubility hauv Methanol | Zoo heev turbidity |
Solubility hauv dej | Soluble hauv dej, 80 g / l 25 ℃ |
Solubility (zoo soluble hauv) | Chloroform, Benzene, Methanol, Acetone |
COA & MSDS | Muaj |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb los yog Off-White Crystalline Hmoov |
Purity / Analysis Method | > 99.0% (HPLC) |
Melting Point | 110.0 ~ 114.0 ℃ |
Insoluble hauv dej | <0.10% |
Moisture (KF) | <0.30% |
Poob Thaum Qhuav | <0.50% (Nyob rau hauv Vacuumn Rau 3 Teev Ntawm 60ºC) |
Ib leeg Impurity | <0.50% |
Tag nrho cov impurities | <1.00% |
Infrared Spectrum | Raws li tus qauv |
1 H NMR Spectrum | Raws li tus qauv |
Test Standard | Enterprise Standard |
Pob:Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov txias thiab qhuav (≤10 ℃) warehouse kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Shipping:Xa mus thoob ntiaj teb los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.
1122-58-3 - Kev pheej hmoo thiab kev nyab xeeb
Risk Codes
R25 - Toxic yog nqos
R34 - Ua rau kub hnyiab
R24/25 -
R36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij.
R27 - Tshuaj lom heev nyob rau hauv kev sib cuag nrog daim tawv nqaij
R36 - Khau qhov muag
R24 - Toxic nyob rau hauv kev sib cuag nrog daim tawv nqaij
R20 - Ua phem los ntawm kev nqus pa
R61 - Tej zaum yuav ua rau muaj mob rau tus menyuam hauv plab
R40 - Cov pov thawj txwv ntawm cov nyhuv carcinogenic
R23/24/25 - Toxic los ntawm kev nqus pa, tiv tauj nrog daim tawv nqaij thiab yog tias nqos.
R67 - Vapors tuaj yeem ua rau qaug zog thiab kiv taub hau
R66 - Rov ua dua tuaj yeem ua rau tawv nqaij qhuav lossis tawg
R21/22 - Ua phem rau ntawm daim tawv nqaij thiab yog tias nqos.
R11 - Cov nplaim hluav taws kub heev
R36/37 - khaus qhov muag thiab ua pa.
R22 - Ua phem yog tias nqos
R19 - Tej zaum yuav tsim cov peroxides tawg
Kev nyab xeeb piav qhia
S36/37/39 - Hnav cov khaub ncaws tiv thaiv, hnab looj tes thiab tiv thaiv qhov muag / ntsej muag.
S45 - Thaum muaj xwm txheej lossis yog tias koj tsis xis nyob, nrhiav kev kho mob tam sim ntawd (qhia daim ntawv lo thaum twg los tau.)
S28A -
S26 - Nyob rau hauv rooj plaub ntawm qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
S28 - Tom qab sib cuag nrog daim tawv nqaij, ntxuav tam sim ntawd nrog xab npum-suds ntau.
S36/37 - Hnav cov khaub ncaws tiv thaiv thiab hnab looj tes tsim nyog.
S53 - Tsis txhob raug - tau txais cov lus qhia tshwj xeeb ua ntej siv.
S27 - Tshem tawm tag nrho cov khaub ncaws tsis huv tam sim ntawd.
S22 - Tsis txhob nqus plua plav.
S16 - Khaws kom deb ntawm qhov chaw hluav taws xob.
UN IDs UN 2811 6.1/PG 2
WGK Germany 3
RTECS US8400000
TSCA T
HS Code 2942000000
Hazard Note Toxic/Corrosive
Hazard Chav Kawm 8
Packing Group II
Toxicity LD50 qhov ncauj hauv luav: 140 mg/kg LD50 dermal Luav 90 mg/kg
4-Dimethylaminopyridine (DMAP) (CAS: 1122-58-3) yog ib qho kev ua tau zoo tshiab catalyst dav siv hauv tshuaj synthesis.Nws muaj peev xwm catalytic siab nyob rau hauv cov organic synthesis, tshuaj synthesis, tshuaj tua kab, dye, tshuaj tsw qab synthesis ntawm acylation, alkylation, etherification thiab lwm yam tshuaj, thiab muaj ib tug heev pom tseeb nyhuv ntawm kev txhim kho yield.Acylation ntawm cawv;Acylation ntawm phenols;Acylation ntawm amines;Acylation ntawm enolates;Cov tshuaj tiv thaiv ntawm isocyanates;Lwm yam kev siv;Hloov cov pab pawg ua haujlwm.
DMAP, yog super nucleophilic acylation catalyst.Lub resonance ntawm electron-pab dimethylamino pawg nyob rau hauv nws cov qauv thiab lub nplhaib niam txiv (pyridine nplhaib) tuaj yeem ua kom muaj nitrogen atom ntawm lub nplhaib kom tau txais kev hloov pauv nucleophilic, uas ua rau muaj kev ua haujlwm siab, tsis tshua muaj cawv thiab amines / acids. ntawm acylation / esterification cov tshuaj tiv thaiv yog li 104 ~ 106 npaug ntawm pyridine.Kev hloov pauv Acyl yog ib qho kev hloov pauv hauv cov xwm txheej thiab cov organic synthesis, uas chiral DMAP yog ib qho asymmetric acyl hloov catalyst.Txij li thaum xyoo 1996, Vedejs thiab Fu pab neeg tau tshaj tawm lub hauv paus chiral thiab planar chiral DMAP catalysts feem, chiral DMAP catalysts tau tsim zoo heev.Ntau yam hauv nruab nrab chiral, planar chiral, spiro chiral thiab central chiral DMAP tau tshaj tawm ib qho tom qab, thiab tau siv zoo hauv ntau qhov kev hloov pauv asymmetric acyl.
DMAP yog ntau yam nucleophilic catalyst rau acylation cov tshuaj tiv thaiv thiab esterifications.Nws kuj tseem ua haujlwm nyob rau hauv ntau yam kev hloov pauv hauv cov organic xws li Baylis-Hillman cov tshuaj tiv thaiv, Dakin-West cov tshuaj tiv thaiv, kev tiv thaiv amines, C-acylations, silylations, kev siv hauv cov khoom ntuj tsim tshuaj, thiab ntau lwm tus.
DMAP tuaj yeem siv los ua cov khoom siv hluav taws xob: Rau acylation ntawm alcohols nrog acid anhydrides nyob rau hauv pab pawg- thiab hnyav-dawb tej yam kev mob rau synthesize coj esters.Nyob rau hauv Baylis-Hillman cov tshuaj tiv thaiv los tsim cov pa roj carbon-carbon daim ntawv cog lus los ntawm kev sib txuas ntawm ib qho activated alkene nrog ib qho aldehyde lossis ketone.
Ib qho zoo heev catalyst rau acylation cov tshuaj tiv thaiv.