4-Hydroxycoumarin CAS 1076-38-6 Purity > 99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom ntawm 4-Hydroxycoumarin (CAS: 1076-38-6) nrog cov khoom zoo.Ruifu Chemical tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, me me thiab ntau ntau muaj.Yuav 4-Hydroxycoumarin,Please contact: alvin@ruifuchem.com
| Tshuaj npe | 4-Hydroxycoumarin |
| Synonyms | 4-Hydroxy-1-Benzopyran-2-ib qho;4-Coumarinyl cawv;4-Coumarinol;4-Hydroxy-2H-Benzo[b]pyran-2-one;4-Hydroxy-2H-Chromen-2-ib qho;4-Hydroxychromen-2-ib qho;Benzotetronic Acid |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, Commercially Manufactured |
| CAS Nr | 1076-38-6 : kuv |
| Molecular Formula | C9H6O3 |
| Molecular Luj | 162.14 g / mol |
| Melting Point | 213.0 ~ 217.0 ℃ (lit.) |
| Qhov ntom | 1.446 ib |
| Dej Solubility | Insoluble hauv dej |
| Solubility | Soluble hauv Ethanol thiab Dimethyl Formamide |
| Cia Temp. | Txias & qhuav qhov chaw |
| COA & MSDS | Muaj |
| Qeb | Pharmaceutical Intermediates |
| Hom | Ruifu Tshuaj |
| Cov khoom | Kev soj ntsuam Standards | Cov txiaj ntsig |
| Qhov tshwm sim | Dawb los yog Yuav luag Dawb Dawb Crystalline Hmoov | Ua raws |
| Melting Point | 213.0 ~ 217.0 ℃ | 213.6 ~ 214.7 ℃ |
| Poob rau ziab | <0.50% | 0.32% |
| Residue ntawm Ignition | <0.20% | 0.08% |
| Heavy Metals (Pb) | ≤10ppm | <10ppm |
| Ib leeg Impurity | <0.30% | Ua raws |
| Purity / Analysis Method | > 99.0% (HPLC) | 99.64% |
| Infrared Spectrum | Raws li tus qauv | Ua raws |
| 1 H NMR Spectrum | Raws li tus qauv | Ua raws |
| Xaus | Cov khoom tau raug kuaj & ua raws li cov lus qhia tshwj xeeb | |
Pob:Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv lub thawv kaw nruj nreem.Khaws rau hauv qhov chaw txias, qhuav thiab zoo-ventilated warehouse.Tiv thaiv los ntawm lub teeb thiab noo noo.Incompatible nrog muaj zog oxidizing cov neeg ua haujlwm thiab cov hauv paus muaj zog.
Shipping:Xa mus thoob ntiaj teb los ntawm huab cua, los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.
4 Txoj kev xeem
4.1 Qhov tshwm sim (kev tshuaj xyuas pom)
4.2 Loss ntawm ziab
4.3 Kev txiav txim siab ntawm 4-Hydroxycoumarin cov ntsiab lus
4.3.1 Kev txiav txim txoj kev
Cov qauv tau yaj nyob rau hauv theem mobile thiab txiav txim siab los ntawm kev ua haujlwm siab ua kua chromatography ntawm C18 kem los ntawm qhov chaw siab tshaj plaws normalization txoj kev.
4.3.2 Reagent
a) Acetonitrile: chromatographic ntshiab (ntshuam);
b) Dej: dej deionized lossis dej distilled thib ob.
4.3.3 Instrument
a) Kev ua haujlwm siab ua kua chromatography;
b) UV-adjustable wavelength spectrometer;
c) Kem tsom xam: C18 kem;
d) Ultrasonic oscillators.
4.3.4 Chromatographic kev khiav hauj lwm tej yam kev mob
a) Txawb theem: acetonitrile: dej: phosphoric acid = 700: 300: 1 (V / V / V);
b) Tus nqi ntws: 1.0ml / min;
c) Kem kub: chav tsev kub;
d) Ntsuas wavelength: 254nm
e) Qauv loj: 20μL
4.3.5 Kev npaj cov tshuaj ntsuam xyuas
Qhov hnyav ntawm cov qauv 20mg (qhov tseeb rau 0.002g), muab tso rau hauv 25ml volumetric lub raj mis, yaj nws nrog lub xov tooj ntawm tes hauv 4.2.4 a) mus rau qhov ntsuas, co nws zoo hauv lub ultrasonic shaker rau tom qab siv.
4.3.6 Kev txiav txim siab txog cov ntsiab lus
Nyob rau hauv cov xwm txheej ntawm 4.3.4 saum toj no, cov kev daws teeb meem yuav tsum tau txiav txim siab tom qab qhov ntsuas tau ruaj khov.
4.3.7 Kev suav
Txoj kev peak area normalization yog siv los xam cov txiaj ntsig.
4.3.8 Tso cai sib txawv
Qhov sib txawv ntawm ob qhov kev ntsuas tsis ntau tshaj 0.5%, thiab qhov ntsuas nruab nrab ntawm qhov ntsuas tau raug coj los ua qhov kev xeem.
4.4 Kev txiav txim siab ntawm melting point.
5 Kev soj ntsuam xyuas
5.1 Txhua batch ntawm cov khoom yuav tsum raug kuaj los ntawm lub chaw soj ntsuam zoo raws li cov khoom nyob rau hauv tus qauv no ua ntej tawm hauv lub Hoobkas.
5.2 Kev txiav txim siab ntawm cov khoom siv
Ib pawg ntawm cov khoom tsim los ntawm kev pub noj kom muaj nuj nqis (kwv yees li 200kg).
5.3 Sampling
Ob lub hnab (cov thoob) raug xaiv los ntawm kev ntim khoom ntawm txhua pawg ntawm cov khoom.Tom qab kuaj thiab sib tov sib npaug, lawv tau muab faib ua 50g los ntawm txoj kev ntawm plaub ntu, uas tau muab faib ua ob ntu, ib qho yog siv rau kev sim thiab lwm yam yog khaws cia rau kev siv.
5.4 Kev txiav txim siab
Txhua batch ntawm cov khoom yuav tsum raug kuaj raws li qhov yuav tsum tau teev nyob rau hauv tus qauv no.Yog tias ib yam khoom ua tsis tau raws li qhov yuav tsum tau ua hauv tus qauv no, nws yuav tsum raug tso cai rov kuaj dua los ntawm kev kuaj ob npaug.Yog tias tseem muaj ib yam khoom uas ua tsis tau raws li qhov yuav tsum tau muaj nyob rau hauv tus qauv no, batch ntawm cov khoom yuav raug txiav txim tsis tsim nyog.
5.5 Kev txiav txim siab
Tus neeg siv muaj cai ua qhov kev lees paub hauv 15 hnub tom qab tau txais cov khoom raws li cov kev cai ntawm tus qauv no.Nyob rau hauv rooj plaub ntawm ib qho kev tsis pom zoo, ob tog tuaj yeem sib tham los daws nws, lossis tso cai rau lub koom haum kev txiav txim plaub ntug tau pom zoo los ntawm ob tog los ua kev txiav txim siab raws li cov kev cai ntawm tus qauv no.
6 Daim ntawv lo thiab daim ntawv lo
Cov cim hauv qab no yuav tsum tau muab tso rau hauv pob khoom:
a) Cov khoom npe;
b) Standard tooj;
c) Net nyhav;
d) Hnub tsim khoom lossis batch tooj;
e) Lub npe thiab chaw nyob ntawm lub Hoobkas;
f) Lub neej txee.
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
Risk Codes
R22 - Ua phem yog tias nqos
R36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij.
Kev nyab xeeb piav qhia
S26 - Nyob rau hauv rooj plaub ntawm qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
S36 - Hnav khaub ncaws tiv thaiv zoo.
WGK Germany 3
RTECS DJ3100000
TSCA Yes
HS Code 2932201000
Hazard Note Irritant
4-Hydroxycoumarin (CAS: 1076-38-6) yog hydroxycoumarin uas yog coumarin uas cov hydrogen ntawm txoj hauj lwm 4 yog hloov los ntawm pawg hydroxy.Nws yog conjugate acid ntawm 4-hydroxycoumarin (1-).
4-Hydroxycoumarin yog cov nroj tsuag tau txais cov tshuaj antioxidant, tiv thaiv lipid peroxidation, nrog rau cov muaj peev xwm inhibitor ntawm HIV-1 Integrase.4-Hydroxycoumarins yog ib chav kawm tseem ceeb heev ntawm cov tshuaj lom neeg lom neeg uas tau siv dav ua cov tshuaj tiv thaiv coagulants-Warfarin thiab Acenocoumarol.
4-Hydroxycoumarin, coumarin derivative, yog ib qho ntawm ntau yam heterocyclic scaffolds thiab nquag siv rau hauv kev sib txuas ntawm ntau cov organic tebchaw.4-Hydroxycoumarin muaj ob qho tib si electrophilic thiab nucleophilic zog.4-Hydroxycoumarin derivatives yog siv los ua cov tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tua kab, tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tiv thaiv kab mob, HIV protease inhibitors thiab tyrosine kinase inhibitors.
4-Hydroxycoumarin koom nrog cov tshuaj tiv thaiv annulation, vim yog cov acidity siab heev ntawm CH daim ntawv cog lus ntawm 3-txoj hauj lwm: cov tshuaj tiv thaiv peb lub ntsiab lus nrog isocyanides thiab dialkyl acetylene dicarboxylates muaj peev xwm annulated 4H-pyrans.
4-Hydroxycoumarin yog ib qho nruab nrab ntawm cov tshuaj thiab tshuaj tua kab.
4-Hydroxycoumarin kuj yog ib qho txuj lom, thiab coumarins tau dav faib rau hauv lub nceeg vaj cog.
