4-(Methylsulfonyl)phenylacetic Acid CAS 90536-66-6 Purity > 99.5% (HPLC) Etoricoxib Intermediate Factory
Tuam Tshoj Chaw tsim tshuaj paus thiab tsum, Intermediates ntawm Etoricoxib
Etoricoxib API CAS 202409-33-4
4- (Methylthio) Phenylacetic Acid CAS 16188-55-9
4- (Methylsulfonyl) Phenylacetic Acid CAS 90536-66-6
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Tshuaj npe | 4- (Methylsulfonyl) phenylacetic Acid |
Synonyms | 4-Methylsulphonylphenylacetic Acid;4- (Methanesulfonyl) phenylacetic Acid;(4-Methanesulfonylphenyl) acetic acid;4-Methylsulfonyl Phenyl Acid;2-(4-(Methylsulfonyl)phenyl) acetic acid;[p-(Methylsulfonyl)phenyl]-Acetic Acid;4-Mesylphenylacetic Acid |
CAS Nr | 90536-66-6 |
CAT Number | Qauv: RF-PI1182 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C9H10O4S |
Molecular Luj | 214.24 Nws |
Melting Point | 136.0 txog 140.0 ℃ |
Qhov ntom | 1.35 Nws |
Solubility | Soluble hauv Methanol |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Off-White Solid Powder |
Purity / Analysis Method | > 99.5% (HPLC) |
Melting Point | 136.0 txog 140.0 ℃ |
Moisture (KF) | <0.50% |
Ib leeg Loj tshaj plaws Impurity | <0.30% |
Tag nrho cov impurities | <0.50% |
Infrared Spectrum | Raws li tus qauv |
Test Standard | Enterprise Standard |
Kev siv | Intermediate of Etoricoxib (CAS: 202409-33-4) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
4-(Methylsulfonyl)phenylacetic Acid (CAS: 90536-66-6) yog ib qho nruab nrab ntawm Etoricoxib (CAS: 202409-33-4).Etoricoxib yog ib hom kev xaiv cyclooxygenase-2 (COX-2) inhibitors tsim los ntawm lub tuam txhab Merck.Etoricoxib yog siv dav hauv kev kho mob osteoarthritis (OA), rheumatoid mob caj dab, ankylosing spondylitis, mob nraub qaum, mob gouty mob caj dab, thawj dysmenorrhea thiab mob postoperative, thiab lwm yam kab mob.Etoricoxib, ib qho kev xaiv COX-2 inhibitor, muaj kev tiv thaiv kab mob, tshuaj tua kab mob thiab tshuaj tua kab mob, tsim nyog rau kev kho mob ntawm cov tsos mob thiab cov tsos mob ntawm tus mob osteoarthritis, nrog rau mob gouty mob caj dab.Etoricoxib yog nqus tau sai, nrog rau qhov ncauj bioavailability ntawm 80 mus rau 100%, thiab ncav cuag qhov siab tshaj plaws plasma concentrations hauv 1 mus rau 2 teev tom qab noj.Cov zaub mov txo qis tus nqi ntawm kev nqus tab sis tsis cuam tshuam rau qhov nqus.Nws nthuav tawm qhov kev tshem tawm ntev ib nrab-lub neej ntawm kwv yees li 22 teev, ua kom pom cov tshuaj plasma plasma pharmacokinetics uas tsis muaj kev sib txuam thaum siv ntau yam.