5-Methylisoxazole-4-Carboxylic Acid CAS 42831-50-5 Leflunomide Intermediate Purity > 99.0% (HPLC)

Lus piav qhia luv luv:

Lub npe tshuaj: 5-Methylisoxazole-4-Carboxylic Acid

Synonyms: 5-Methyl-4-Isoxazolecarboxylic Acid

CAS: 42831-50-5 Nr

Purity:> 99.0% (HPLC)

Dawb rau daj ntseg daj crystalline hmoov, tsw ntxhiab

Intermediate ntawm Leflunomide (CAS: 75706-12-6)

Hu rau: Dr. Alvin Huang

Txawb/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Product Detail

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Nqe lus piav qhia:

Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom ntawm 5-Methylisoxazole-4-Carboxylic Acid (CAS: 42831-50-5) nrog cov khoom zoo.Ruifu tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, kev pabcuam zoo, me me thiab ntau ntau muaj.Yuav 5-Methylisoxazole-4-Carboxylic Acid,Please contact: alvin@ruifuchem.com

Chemical Properties:

Tshuaj npe	5-Methylisoxazole-4-Carboxylic Acid
Synonyms	5-Methyl-4-Isoxazolecarboxylic Acid
impurity	Leflunomide EP Impurity D / Leflunomide BP Impurity D
Tshuag xwm txheej	Hauv Tshuag, Kev Lag Luam Loj
CAS Nr	42831-50-5
Molecular Formula	C5H5NO3
Molecular Luj	127.10 g / mol
Melting Point	145.0 ~ 149.0 ℃ (lit.)
Qhov ntom	1.348 ± 0.06 g / cm3
Cia Temp.	Qhov chaw txias & qhuav (2 ~ 8 ℃)
COA & MSDS	Muaj
Hom	Ruifu Tshuaj

Specifications:

Cov khoom	Kev soj ntsuam Standards	Cov txiaj ntsig
Qhov tshwm sim	Dawb rau daj ntseg daj crystalline hmoov, tsw ntxhiab	Ua raws
Melting Point	145.0 txog 149.0 ℃	147.8 ~ 148.5 ℃
Poob rau ziab	≤0.50%	0.13%
Residue ntawm Ignition	≤0.10%	0.04%
Heavy Metals (Pb)	≤ 0.002%	<0.002%
3-Methyl Isomeric Compound	≤ 0.20%	<0.20%
Purity / Analysis Method	> 99.0% (HPLC)	99.74%
Infrared Spectrum	Raws li tus qauv	Ua raws
1 H NMR Spectrum	Raws li tus qauv	Ua raws
Xaus	Cov khoom tau raug kuaj & ua raws li cov lus qhia tshwj xeeb
Siv	Pharmaceutical Intermediate ntawm Leflunomide (CAS: 75706-12-6)

Pob / Cia /Shipping:

Pob:Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv lub thawv kaw nruj nreem.Khaws rau hauv qhov chaw txias, qhuav (2 ~ 8 ℃) thiab lub tsev tso cua txias kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Shipping:Xa mus thoob ntiaj teb los ntawm huab cua, los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.

Qhov zoo:

Muaj peev xwm txaus: Muaj cov chaw txaus thiab cov kws tshaj lij

Kev Pabcuam Kev Ua Haujlwm: Ib qho kev pabcuam kev yuav khoom

Pob OEM: Kev cai pob thiab daim ntawv lo muaj

Kev xa khoom sai: Yog tias nyob hauv Tshuag, peb hnub xa khoom lav

Stable Supply: Khaws cov khoom tsim nyog

Kev them nyiaj yug Technical: Technology tov muaj

Kev Pabcuam Synthesis: Ntau yam ntawm grams mus rau kilos

High Quality: Tsim kom muaj kev ruaj ntseg zoo

FAQ:

Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.

Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.

Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.

ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.

Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.

Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.

MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.

Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.

Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.

Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.

Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.

Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.

42831-50-5 - Kev pheej hmoo thiab kev nyab xeeb:

Risk Codes
R36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij.
R37/38 - Kab mob ua pa thiab tawv nqaij.
R36 - Khau qhov muag
R10 - Flammable
Kev nyab xeeb piav qhia
S22 - Tsis txhob nqus plua plav.
S26 - Nyob rau hauv rooj plaub ntawm qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
S36/37/39 - Hnav cov khaub ncaws tiv thaiv, hnab looj tes thiab tiv thaiv qhov muag / ntsej muag.
S36 - Hnav khaub ncaws tiv thaiv zoo.
S16 - Khaws kom deb ntawm qhov chaw hluav taws xob.
WGK Germany 3
HS Code 2917399090
Hazard Class IRRITANT

Daim ntawv thov:

5-Methylisoxazole-4-Carboxylic Acid (CAS: 42831-50-5) yog ib qho nruab nrab rau kev sib txuas ntawm Leflunomide (CAS: 75706-12-6).Leflunomide yog ib hom tshuaj isoxazole immunosuppressive nrog kev tiv thaiv kev loj hlob, niaj hnub pharmacology faib cov khoom no raws li cov tshuaj tua kab mob, tshuaj tua kab mob thiab tshuaj tiv thaiv kab mob.Cov khoom no tuaj yeem hloov pauv sai sai rau cov metabolites nquag thiab ua lub luag haujlwm los ntawm lub siab thiab plab hnyuv cytoplasm thiab microsomes, nws;Lub ntsiab mechanism yog thaum lub sij hawm DNA synthesis, inhibiting ib tug tseem ceeb enzyme-DHODH (DHODH) kev ua si, thiaj li hais tias cov nucleotides nyob rau hauv lub B lymphocyte depleted, nws terminates lub biosynthesis ntawm DNA thiab RNA, lub hlwb tsis tuaj yeem nkag mus rau s theem, thiab thaum kawg ua tsis tau. proliferate, ua rau muaj kev tiv thaiv rheumatic, nws yog tsim nyog rau kev kho mob ntawm cov neeg laus uas muaj active rheumatoid mob caj dab, ankylosing spondylitis, nws muaj peev xwm qeeb pob txha puas, alleviate cov tsos mob thiab cov tsos mob.Tsis tas li ntawd, leflunomide tuaj yeem cuam tshuam cov tyrosine kinase kev ua haujlwm, yog li inhibiting kev loj hlob ntawm T cell, B cell thiab cov hlwb tsis muaj zog, tab sis nws kuj tuaj yeem, los ntawm biosynthesis inhibition ntawm cyclooxygenase-2 (COX2), inhibit prostaglandin synthesis thiab tawm tsam. inflammatory teebmeem thiab inhibit mast hlwb thiab basophils histamine tso tawm.Thaum cov khoom no siv rau hauv cov neeg mob hloov pauv hauv nruab nrog cev, kev hloov kho koob tshuaj yog qhov nyuaj, nws yog siv los kho mob rheumatoid mob caj dab thiab lwm yam kab mob autoimmune.