6-Amino-5-Bromoquinoxaline CAS 50358-63-9 Purity > 99.0% (HPLC) Brimonidine Tartrate Intermediate
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Tshuaj npe | 6-Amino-5-Bromoquinoxaline |
Synonyms | 5-Bromoquinoxalin-6-Amine;5-Bromo-6-Quinoxalinamine;5-Bromo-6-Aminoquinoxaline |
impurity | Brimonidine EP impurity B |
CAS Nr | 50358-63-9 |
CAT Number | TIAB SA 2515 |
Tshuag xwm txheej | Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 35 Tons ib Hlis |
Molecular Formula | C8H6BrN3 |
Molecular Luj | 224.06 Nws |
Melting Point | 153.0 txog 157.0 ℃ |
Qhov ntom | 1.744 ± 0.06 g / cm3 |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Brown mus rau lub teeb-daj hmoov |
Purity / Analysis Method | > 99.0% (HPLC) |
Melting Point | 153.0 ~ 157.0 ℃ |
Poob rau ziab | <1.00% |
Max.Tus kheej impurity | <0.50% |
Tag nrho cov impurities | <1.00% |
Infrared Spectrum | Raws li tus qauv |
Proton NMR Spectrum | Raws li tus qauv |
Test Standard | Enterprise Standard |
Kev siv | Intermediate ntawm Brimonidine Tartrate (CAS: 70359-46-5) |
Melting Point
Siv txoj kev ntsuas dav dav thiab nce qhov kub ntawm 1.5 ℃ / feeb.Nws yuav tsum yaj ntawm 153.0 ~ 157.0 ℃
Poob rau ziab
Tsis ntau tshaj 1.0% Txiav txim siab ntawm 1.0g los ntawm ziab hauv qhov cub ntawm 105 ℃ txog qhov hnyav tas li
Related compounds (HPLC)
Chromatographic system:
Kem: ODS, C18,
Ntes wavelengh: 264nm
Flow tus nqi: 1.0 ml / min
Mobile theem:
Npaj ib lub lim dej thiab degassed sib tov ntawm buffer ( yaj 2.6g Sodium 1-heptanesulfonate hauv 690ml dej)-methanol-glacial acetic acid-triethylamine (690:310:7.5:2.5).
Kev npaj ua piv txwv:
Dissolve ib qho piv txwv hnyav 25.0mg hauv 25ml mobile theem.
Txheej txheem:
Txhaj ntim ntawm 10 l ntawm cov qauv kev daws teeb meem thiab sau cov chromatograms rau 4 zaug ntawm lub sijhawm khaws cia ntawm lub ntsiab ncov.Xam cov impurity peaks txo lub ncov dawb paug.Tag nrho
impurities tsis ntau tshaj 1.00%, ib tus neeg impurity tsis ntau tshaj 0.50%.
Synthesis Route ntawm 6-Amino-5-Bromoquinoxaline (CAS: 50358-63-9)
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
Yuav Yuav Li Cas?Please contact: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Russia, Kauslim Teb, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Zoo heev, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev pabcuam kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
6-Amino-5-Bromoquinoxaline (CAS: 50358-63-9) yog ib qho tseem ceeb nruab nrab ntawm quinoxaline derivatives.6-Amino-5-Bromoquinoxaline yog siv los ua tshuaj nruab nrab, ib qho nruab nrab ntawm Brimonidine Tartrate (CAS: 70359-46-5).Brimonidine yog ib qho kev xaiv α2-receptor blocker, ua tiav los ntawm Asmeskas Tuam Txhab Allergan, uas yog tshuaj kho qhov muag.Nws tuaj yeem txo qhov siab intraocular siab (IOP).Brimonidine Tartrate ophthalmic tov saling nyob rau hauv kev ua lag luam yog brimonidine tartrate daim ntawv, uas yog ib tug zoo IOP-txo cov tshuaj rau mob qhib-angle glaucoma thiab ocular hypertension kev kho mob ntawm cov neeg mob, tab sis kuj rau argon laser IOP qib.Brimonidine Tartrate ophthalmic tov muaj ib tug dual mechanism ntawm kev txiav txim los ntawm kev txo cov aqueous lom zem ntau lawm thiab ua rau cov xim txheej ntawm cov kua scleral outflow kho lub hom phiaj.Tom qab tso rau hauv lub qhov muag, cov nyhuv yog nrawm, thiab nws tuaj yeem ncav cuag lub ncov thaum siv txog li 2h, thiab lub sijhawm zoo tuaj yeem tswj tau 12h.Ntshav tsuas tuaj yeem kuaj pom cov tshuaj.Cov khoom no muaj cov metabolism hauv thawj zaug hauv lub siab, thiab cov metabolites tawm hauv cov zis los ntawm ob lub raum.Kev nqus thiab kev faib tawm tsis raug cuam tshuam, thiab cov neeg laus tsis tas yuav hloov cov koob tshuaj.Brimonidine Tartrate ophthalmic tov piv nrog rau lwm cov α-blockers, cov rog-soluble yog me me, thaum nws tsis yooj yim mus hla cov ntshav-hlwb barrier thiab tsis tsim sedation, hypotension thiab lwm yam zoo xws li clonidine central adverse reactions.