6-Mercaptopurine 6-MP CAS 50-44-2 Assay 97.0 ~ 102.0% Hoobkas USP Txuj
Chaw tsim khoom, siab purity, coj mus muag ntau lawm
Lub npe tshuaj: 6-Mercaptopurine
CAS: 50-44-2 Nr
| Tshuaj npe | 6-Mercaptopurine |
| Synonyms | Mercaptopurine;6-MP;6-Mercaptopurine (monohydrate) |
| CAS Nr | 50-44-2 ib |
| CAT Number | Qauv: RF-PI487 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
| Molecular Formula | C5H4N4S |
| Molecular Luj | 152.18 Nws |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Yellow Crystalline hmoov |
| Assay | 97.0 ~ 102.0% ntau |
| Melting Point | ≥300 ℃ |
| Organic Volatile Impurities | Ua raws li qhov yuav tsum tau ua |
| Poob rau ziab | ≤ 11.0% |
| Residue ntawm Ignition | ≤ 0.20% |
| Hypoxanthine | ≤ 1.0% |
| Hnyav Hlau | ≤10ppm |
| Test Standard | Tebchaws Asmeskas Pharmocopoeia (USP) |
| Kev siv | API;Pharmaceutical Intermediates |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo.
6-Mercaptopurine (CAS: 50-44-2) yog siv dav siv tshuaj tua kab mob thiab tshuaj tiv thaiv kab mob uas inhibits de novo purine synthesis los ntawm kev koom ua ke ntawm thiopurine methyltransferase metabolites rau hauv DNA thiab RNA.6-Mercaptopurine yog ib tug purine analogue uas ua raws li ib tug antagonist ntawm endogenous purines thiab tau dav siv raws li antileukemic tus neeg sawv cev thiab tshuaj tiv thaiv kab mob.Mercaptopurine inhibits purine nucleotide synthesis thiab metabolism los ntawm inhibiting ib qho enzyme hu ua Phosphoribosyl pyrophosphate amidotransferase (PRPP Amidotransferase).Mercaptopurine cuam tshuam nrog nucleotide interconversion thiab glycoprotein synthesis.Mercaptopurine, muag raws li lub npe Purinethol, tshwj xeeb tshaj yog siv los kho mob lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn's disease, thiab ulcerative colitis.
