6-O-Methylguanine CAS 20535-83-5 Nelzarabine Intermediate Factory
Supply Nrog High Purity, Commercial Production
Lub npe tshuaj: 6-O-Methylguanine
CAS: 20535-83-5 Nr
| Tshuaj npe | 6-O-Methylguanine |
| Synonyms | 2-Amino-6-Methoxypurine |
| CAS Nr | 20535-83-5 |
| CAT Number | Qauv TSIS MUAJ: RF-PI509 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
| Molecular Formula | C6H7 N5 O |
| Molecular Luj | 165.16 Nws |
| Melting Point | ≥300 ℃ (lit.) |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Off-White Crystalline Powder |
| Assay / Analysis Method | ≥98.5% (HPLC) |
| Poob rau ziab | ≤0.50% |
| Residue ntawm Ignition | ≤0.50% |
| Tag nrho cov impurities | ≤ 1.5% |
| Test Standard | Enterprise Standard |
| Kev siv | Intermediate of Nelzarabine (CAS: 121032-29-9), T-ALL & T-LBL |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo.
6-O-Methylguanine (CAS: 20535-83-5) tuaj yeem siv los ua qhov nruab nrab hauv kev sib txuas ntawm Nelzarabine (CAS: 121032-29-9).Nelarabine yog prodrug rau deoxyguanosine analogue-9-beta-D-arabinofuranosyl guanine (ara-G).Nelarabine demethylates hauv lub luag haujlwm ntawm adenosine deaminase (ADA) thiab hloov mus ua ara-G.Nelarabine tau ua tiav thawj zaug los ntawm GlaxoSmithKline.Thaum Lub Kaum Hli 28, 2005 raws li kev pom zoo los ntawm US Food and Drug Administration, nws tau los ua ib qho tshuaj tshiab los kho T-cell mob lymphoblastic leukemia (T-ALL) thiab T-Cells lymphoblasticlymphoma (T-LBL) uas tiv taus tsawg kawg. ob hom kev siv tshuaj khomob los yog rov ua dua tomqab pib kho.Cov tshuaj tshiab no tau teev npe hauv Tebchaws Meskas hauv xyoo 2006.
