7-Fluoro-6-Nitroquinazolin-4(1H)-one CAS 162012-69-3 Purity > 99.0% (HPLC) Afatinib Dimaleate Intermediate Factory Featured Duab

7-Fluoro-6-Nitroquinazolin-4(1H)-ib CAS 162012-69-3 Purity > 99.0% (HPLC) Afatinib Dimaleate Intermediate Factory

Lus piav qhia luv luv:

Lub npe tshuaj: 7-Fluoro-6-Nitroquinazolin-4(1H)-ib

CAS: 162012-69-3 Nr

Purity:> 99.0% (HPLC)

Yellow rau Reddish Yellow Crystal lossis hmoov

Intermediate of Afatinib Dimaleate (CAS: 850140-73-7)

High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com

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Product Detail

Yam khoom

Khoom cim npe

Nqe lus piav qhia:

Ruifu Chemical Supply Intermediates ntawm Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
Tom ntej: Dimethylamino Acetaldehyde Diethyl Acetal CAS 3616-56-6
Tom ntej: Trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-ib CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineCAS Nr .: 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineCAS Nr .: 314771-88-5

Chemical Properties:

Tshuaj npe	7-Fluoro-6-Nitroquinazolin-4(1H)-ib
Synonyms	7-Fluoro-6-Nitroquinazolin-4(3H)-ib;7-Fluoro-4-Hydroxy-6-Nitroquinazoline;7-Fluoro-6-Nitroquinazolin-4-ol;7-Fluoro-6-Nitro-4-Hydroxyquinazoline;7-Fluoro-6-Nitro-1H-Quinazolin-4-ib
CAS Nr	162012-69-3
CAT Number	Tus Qauv Zauv: RF-PI2025
Tshuag xwm txheej	Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons
Molecular Formula	C8H4FN3O3
Molecular Luj	209.13 Nws
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Yellow rau Reddish Yellow Crystal lossis hmoov
1 H NMR Spectrum	Raws li tus qauv
Purity / Analysis Method	> 99.0% (HPLC)
Poob rau ziab	<0.50%
Tag nrho cov impurities	<1.00%
Proton NMR Spectrum	Raws li tus qauv
Test Standard	Enterprise Standard
Kev siv	Intermediate of Afatinib Dimaleate (CAS: 850140-73-7)

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo

Qhov zoo:

FAQ:

Daim ntawv thov:

7-Fluoro-6-Nitroquinazolin-4(1H)-one (CAS: 162012-69-3) yog ib qho nruab nrab ntawm Afatinib Dimaleate (CAS: 850140-73-7).Afatinib yog ib tug irreversible ErbB tsev neeg ntawm blockers uas suppress cov ntaub ntawv kis tau tus mob thiab thaiv txoj kev loj koom nyob rau hauv mob qog noj ntshav cell loj hlob thiab faib.Vim tias ErbB tsev neeg cov ntaub ntawv hloov pauv cov txheej txheem tuaj yeem tshwm sim los ntawm ntau homodimers thiab heterodimers, ib txhij inhibition ntawm ntau tus neeg hauv tsev neeg ErbB (xws li EGFR, HER2, ErbB3 thiab ErbB4) tuaj yeem cuam tshuam cov ntaub ntawv xa mus hauv qab.Afatinib yog ib qho tshuaj pom zoo rau kev kho mob uas tsis yog mob ntsws me me (NSCLC), tsim los ntawm Boehringer Ingelheim.Nws ua raws li angiokinase inhibitor.Zoo li lapatinib thiab neratinib, afatinib yog tyrosine kinase inhibitor (TKI) uas tseem cuam tshuam tsis zoo rau tib neeg epidermal kev loj hlob receptor 2 (Her2) thiab epidermal growth factor receptor (EGFR) kinases.Afatinib tsis yog tsuas yog tawm tsam EGFR kev hloov pauv tau tsom los ntawm thawj tiam TKIs likeerlotinib lossis gefitinib, tab sis kuj tawm tsam cov tsis nkag siab rau cov qauv kev kho no.Vim tias nws cov haujlwm ntxiv tawm tsam Her2, nws tau raug tshuaj xyuas mob qog noj ntshav nrog rau lwm yam EGFR thiab Her2 uas tau tsav cov qog noj ntshav.