7-Hydroxy-3,4-Dihydro-2(1H)-Quinolinone CAS 22246-18-0 Purity > 99.0% (HPLC) Aripiprazole Intermediate Factory
Chaw tsim tshuaj paus Supply Intermediates ntawm Aripiprazole Nrog High Purity
Aripiprazole API CAS 129722-12-9
Tom ntej: 1-(2,3-Dichlorophenyl) Piperazine Hydrochloride CAS 119532-26-2
7-Hydroxy-3,4-Dihydro-2(1H)-Quinolinone CAS 22246-18-0
7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone CAS 129722-34-5
| Tshuaj npe | 7-Hydroxy-3,4-Dihydro-2(1H)-Quinolinone |
| Synonyms | 3,4-Dihydro-7-Hydroxy-2(1H)-Quinolinone;7-Hydroxy-3,4-Dihydrocarbostyril;7-Hydroxy-2-oxo-1,2,3,4-Tetrahydroquinoline;7-Hydroxycarbostyril;Aripiprazole impurity 5;Aripiprazole EP Impurity A |
| CAS Nr | 22246-18-0 |
| CAT Number | RF-PI 1981 |
| Tshuag xwm txheej | Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 60MT / Xyoo |
| Molecular Formula | C9H9NO2 |
| Molecular Luj | 163.18 Nws |
| Solubility | Soluble hauv Methanol |
| Qhov ntom | 1.282 ± 0.060g / cm3 |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Pale Daj lossis Yuav luag Dawb Hmoov |
| Purity / Analysis Method | > 99.5% (HPLC, Cheeb Tsam Feem Xyuam) |
| Melting Point | 229.0 ~ 235.0 ℃ |
| Poob rau ziab | <0.50% |
| Cov ntsiab lus dej (KF) | <0.50% |
| Qhov siab tshaj plaws ib leeg impurity | <0.30% |
| Tag nrho cov impurities | <0.50% |
| Infrared Spectrum | Raws li tus qauv |
| Test Standard | Enterprise Standard |
| Kev siv | Intermediate of Aripiprazole (CAS: 129722-12-9) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
Methyl 3-Bromobenzoate (CAS 618-89-3) tuaj yeem siv los ua tus thawj coj ntawm Aripiprazole (CAS: 129722-12-9).Aripiprazole yog ib yam tshiab ntawm cov lipid soluble quinoline derivatives, nws cov tshuaj pharmacological yam ntxwv yog tias nws tsis yog tsuas yog postsynaptic dopamine D 2 receptor antagonist, tab sis kuj yog presynaptic dopamine D 2 receptor agonist, nws kuj tuaj yeem ua rau D 1, D 3, D 4 receptors;Aripiprazole muaj ob txoj kev ua haujlwm ntawm ib feem los yog receptor antagonistic ntawm 5-HT 1A receptor;Nws muaj qhov ua tsis ncaj ncees kiag li ntawm 5-HT 2A receptor.Qhov no feature yog txawv los ntawm thawj tiam, thiab atypical antipsychotics uas yog mus rau lub thib ob tiam antipsychotic tshuaj, thiab yog li ntawd nws yog hu ua dopamine system stabilizer los yog thib peb tiam antipsychotic.Txij li thaum nws tau muag hauv khw, Aripiprazole feem ntau yog siv rau hauv kev kho mob schizophrenia, kev kho mob ntawm kev puas siab puas ntsws thiab lwm yam kev puas siab puas ntsws.Raws li cov ntaub ntawv, aripiprazole muaj qhov cuam tshuam loj rau tus mob schizophrenia zoo thiab tsis zoo cov tsos mob thiab kev ntxhov siab, kev nyuaj siab, kev txawj ntse, thaum muaj kev nyab xeeb dua.Aripiprazolekuj tau tshaj tawm tias cov tshuaj kuj tuaj yeem kho lwm yam kev puas siab puas ntsws, xws li kev xav tsis zoo manic episodes, senile dementia cuam tshuam nrog kev puas siab puas ntsws, ntxhov siab vim, me nyuam kev coj cwj pwm tsis zoo, kev nyuaj siab.
