7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1 Purity > 99.0% (GC) Agomelatine Intermediate
Tuam Tshoj Chaw tsim tshuaj paus thiab tsum ntawm Agomelatine Intermediates
Agomelatine CAS 138112-76-2
7-Methoxy-1-Tetralone CAS 6836-19-7
Tom ntej: 7-Methoxy-1-Naphthaleneacetic Acid CAS 6836-22-2
7-Methoxy-1-Naphthylacetonitrile CAS 138113-08-3
Tom ntej: 7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1
Please contact: alvin@ruifuchem.com
| Tshuaj npe | 7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester |
| Synonyms | Ethyl 2-(7-Methoxynaphthalen-1-yl)acetate |
| CAS Nr | 6836-21-1 : kuv |
| CAT Number | TIAB SA 2687 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
| Molecular Formula | C15H16O3 |
| Molecular Luj | 244.29 Nws |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Lub teeb daj pob tshab kua |
| Purity / Analysis Method | > 99.0% (GC) |
| Dej (los ntawm Karl Fischer) | <0.50% |
| Yam khoom muaj feem | <1.00% |
| Infrared Spectrum | Raws li tus qauv |
| NMR Spectrum | Raws li tus qauv |
| Test Standard | Enterprise Standard |
| Kev siv | Pharmaceutical Intermediate ntawm Agomelatine (CAS: 138112-76-2) |
Pob: Fluorinated Lub raj mis, 25kg / chim, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
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Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
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Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
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7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester (CAS: 6836-21-1) yog ib qho tseem ceeb organic synthetic intermediate, siv tau los ua tshuaj intermediate ntawm Agomelatine (CAS: 138112-76-2).Agomelatine, uas yog tsim los ntawm Fabkis Servier tuam txhab, yog lub ntiaj teb thawj melatonin receptors MT1 thiab MT2 agonist chav kawm ntawm antidepressants.Nws siv rau kev kho mob ntawm cov neeg laus uas muaj kev nyuaj siab loj.Agomelatine yog ib qho tshuaj tiv thaiv kev nyuaj siab.Agomelatine yog ib qho agonist ntawm melatonin (MT) receptors thiab derivative ntawm melatonin.Nws khi rau MT1 thiab MT2 receptors (Kis = 0.14 thiab 0.41 nM, ntsig txog) thiab muaj EC50 tus nqi ntawm 0.1 nM hauv [35S]GTPγS binding assay siv CHO hlwb qhia MT2 receptors.Nws raug cais raws li norepinephrine-dopamine disinhibitor (NDDI) vim nws antagonism ntawm 5-HT2C receptor.Ua kom 5-HT2C receptors los ntawm serotonin inhibits dopamine thiab norepinephrine tso.
