S-Adenosyl-L-Methionine (Ademethionine; SAMe) CAS 29908-03-0
Ruifu Chemical yog cov chaw tsim khoom ntawm S-Adenosyl-L-Methionine (Ademetionine; SAMe) (CAS: 29908-03-0) nrog cov khoom zoo.Ruifu Chemical tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, kev pabcuam zoo heev, me me thiab ntau ntau muaj.Yuav S-Adenosyl-L-Methionine,Please contact: alvin@ruifuchem.com
| Tshuaj npe | S-Adenosyl-L-Methionine |
| Synonyms | Ademethionine;S-Adenosylmethionine;SAIB;SAM;AdoMet |
| Tshuag xwm txheej | Hauv Tshuag, Kev Lag Luam Ntau Lawm |
| CAS Nr | 29908-03-0, ib |
| Molecular Formula | C15H22N6O5S |
| Molecular Luj | 398,44 g / mol |
| Melting Point | 267.0 ~ 269.0 ℃ |
| rhiab heev | Hygroscopic heev |
| Dej Solubility | Soluble hauv dej |
| tsw & saj | Yam ntxwv |
| COA & MSDS | Muaj |
| Qauv | Muaj |
| Keeb kwm | Shanghai, Suav |
| Hom | Ruifu Tshuaj |
| Cov khoom | Specifications | Cov txiaj ntsig |
| Qhov tshwm sim | Yuav luag Dawb Fine Hmoov (Hygroscopic heev) | Kev lees paub |
| Solubility | Soluble hauv dej | |
| Kev txheeb xyuas | 1. Tshuaj tiv thaiv | Cov tshuaj tiv thaiv zoo |
| 2. IR: Raws li cov spectrum tau txais nrog RS | Kev lees paub | |
| 3. Lub sijhawm khaws cia ntawm qhov siab tshaj plaws raws li kev thov | Kev lees paub | |
| Acid nqi | 1.5 ~ 2.5 hli | 1.9 |
| Clarity thiab xim ntawm kev daws | Tsis muaj xim ntau dua li RS Y1 | Kev lees paub |
| Dej los ntawm Karl Fischer | ≤ 3.00% | 2.2% |
| Residue ntawm Ignition | ≤ 0.30% | 0.14% |
| Heavy Metals (Pb) | ≤10ppm | <10ppm |
| Endotoxin | ≤0.3EU / mg | Kev lees paub |
| Microbiological | Yuav tsum ua raws li qhov yuav tsum tau ua | |
| Tag Nrho Phaj suav | ≤1000cfu / g | 55cfu/g |
| Poov & Pwm | ≤100cfu / g | 12 cfu/g |
| E. Coli | Tsis muaj / 10g | Ua raws |
| S. Aureus | Tsis muaj / 10g | Ua raws |
| Salmonella | Tsis muaj / 10g | Ua raws |
| S-Adenosyl-L-homocysteine | ≤0.50% | 0.10% |
| Methioadenosine | ≤ 1.00% | 0.24% |
| Adenine | ≤0.50% | 0.09% |
| Yam khoom muaj feem | ||
| Lwm yam Impurities loj tshaj | ≤ 0.20% | 0.01% |
| Lwm yam Impurities tag nrho | ≤0.50% | 0.006% |
| (S, S) Isomer | > 62.0% | 79.4% |
| Butanedisulfonate | 46.0 ~ 49.0% (Raws li qhuav) | 47.5% |
| Ademethionine | 50.0 ~ 53.0% (Raws li qhuav) | 52.1% |
| Cov ntsiab lus tag nrho | > 97.5% (Raws li qhuav) | 99.6% |
| Xaus | Cov khoom tau raug kuaj thiab ua raws li cov lus qhia tshwj xeeb | |
| Txee lub neej | 2 Xyoo Thaum Yuav Tsum Tau Zoo | |
Pob:Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws lub thawv kaw kom nruj thiab khaws cia rau hauv qhov chaw txias, qhuav thiab zoo-ventilated warehouse kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Shipping:Xa mus thoob ntiaj teb los ntawm huab cua, los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
Risk Codes R49 - Tej zaum yuav ua rau mob qog noj ntshav los ntawm kev nqus pa
R23 - Toxic los ntawm kev nqus pa
R34 - Ua rau kub hnyiab
Kev Nyab Xeeb Kev Nyab Xeeb S53 - Tsis txhob raug - tau txais cov lus qhia tshwj xeeb ua ntej siv.
S23 - Tsis txhob ua pa.
S36/37/39 - Hnav cov khaub ncaws tiv thaiv, hnab looj tes thiab tiv thaiv qhov muag / ntsej muag.
S45 - Thaum muaj xwm txheej lossis yog tias koj tsis xis nyob, nrhiav kev kho mob tam sim ntawd (qhia daim ntawv lo thaum twg los tau.)
HS Code 2934999099
S-Adenosyl-L-Methionine (Ademetionine; SAMe) (CAS: 29908-03-0) yog ib hom cosubstrate koom nrog hauv kev hloov methyl pawg.SAMe tau tshawb pom thawj zaug hauv tebchaws Ltalis los ntawm GL Cantoni hauv xyoo 1952, SAMe yog ib qho molecule uas tsim los ntawm tag nrho cov nyob hauv hlwb, tuaj yeem tiv thaiv kab mob siab, txhawb nqa cov ntaub so ntswg cartilaginous thiab concrescence, tuaj yeem pab tiv thaiv kev nyuaj siab, alzheimer's kab mob, kab mob siab, thiab mob. osteoarthritis, Same yog tam sim no universerally lees paub tias yog ib qho tseem ceeb tshuaj kho mob siab.Tam sim no SAMe feem ntau siv hauv kev lag luam tshuaj, kev noj qab haus huv kev lag luam zaub mov ob qho tib si ntawm kev lag luam hauv tsev thiab thoob ntiaj teb.SAME yog muag hauv Tebchaws Meskas raws li kev noj haus ntxiv.
1. S-Adenosyl-L-Methionine yog ib qho khoom noj zoo rau lub siab, uas tuaj yeem tiv thaiv tau cawv, tshuaj thiab daim siab cell puas;
2. S-Adenosyl-L-Methionine muaj kev tiv thaiv tseem ceeb ntawm cov kab mob siab ua haujlwm ntev thiab lwm yam ua rau lub siab puas tsuaj, kab mob plawv, mob qog noj ntshav thiab lwm yam.
3. S-Adenosyl-L-Methionine tau pom tias muaj txiaj ntsig zoo li cov tshuaj kho mob caj dab thiab kev nyuaj siab loj.
4. Hauv Tebchaws Meskas, SAM raug muag ua khoom noj khoom haus ntxiv raws li kev lag luam lub npe SAM-e (tseem sau SAME lossis SAME).Qee qhov kev tshawb fawb tau pom tias noj SAM tsis tu ncua tuaj yeem pab tiv thaiv kev nyuaj siab, kab mob siab, thiab mob osteoarthritis.Ntau qhov kev sim tshuaj tau pom tias nws zoo rau kev nyuaj siab, qee yam kab mob siab thiab osteoarthritis.Tag nrho lwm cov cim qhia tsis tau lees paub.
5. Clinically siv los txhim kho daim siab ua haujlwm.Kev sib xyaw nrog L-DOPA rau kev kho mob Parkinson tus kab mob tuaj yeem txhim kho qhov ua tau zoo ntawm L-dopa thiab txo cov kev mob tshwm sim.Kev mob hauv zos, kev ntxhov siab ib ntus thiab insomnia ntawm qhov chaw txhaj tshuaj tuaj yeem pom.
S-Adenosyl-L-Methionine (Ademetionine; SAMe) (CAS: 29908-03-0) kuj muaj kev kho mob zoo rau kev mob caj dab, fibrous leeg, migraine thiab lwm yam kab mob, thiab muaj kev phiv me ntsis.Thaum ntxov li xyoo 1970s, SAMe tau siv los ua tshuaj kho mob caj dab hauv Tebchaws Europe.Xyoo 1999, US FDA tau pom zoo SAMe ua cov khoom noj qab haus huv thiab tau dhau los ua ib qho khoom noj khoom haus zoo tshaj plaws hauv Tebchaws Meskas.
S-Adenosyl-L-Methionine yog npaj los ntawm cov tshuaj synthesis, fermentation thiab enzymatic transformation.Txoj kev fermentation yog ntxiv cov precursor L-Methionine rau hauv nruab nrab nruab nrab uas muaj C thiab N qhov chaw, thiab ib tug loj npaum li cas ntawm S-Adenosylmethionine yuav tau txais los ntawm culturing microbial hlwb.Qhov no tam sim no yog txoj hauv kev tseem ceeb rau kev tsim khoom ntawm S-Adenosylmethionine.Ntawm lawv, cov kab mob uas siv rau fermentation tuaj yeem tau txais los ntawm kev tshuaj xyuas lossis kev tsim kho dua tshiab, uas tau sau tseg hauv ntau cov ntawv thiab patents hauv tsev thiab txawv teb chaws.Qee cov kev tshawb fawb tau muab ib txoj kev npaj ntawm S-adenosylmethionine, siv polyhydroxy organic reagents los tiv thaiv kev ua haujlwm ntawm enzyme, siv adenosine triphosphate precursor, L-Methionine thiab phosphate ions ua substrates, qabzib lossis / thiab maltose ua lub zog pub dawb, ntxiv cov khoom xyaw. ntawm hlau ions, thiab siv ib tug permeable ntau lawm strain catalyze zus tau tej cov S-Adenosylmethionine nyob rau hauv tag nrho cov hlwb.Siv cov txheej txheem ntawm cov hlau ions los tswj cov metabolic txaus los txhim kho lub zog nws tus kheej coupling efficiency, ntxiv cov organic reagents los tiv thaiv cov kev ua ntawm cov kab mob thiab enzymes, siv ib tug permeable ntau lawm hom los npaj S-Adenosylmethionine, shorten lub sij hawm synthesis, thiab ua kom cov khoom sib sau sab nraud ntawm tes, uas tuaj yeem txuag tus nqi ntawm kev sib cais tom qab thiab ua kom yooj yim rau cov kauj ruam ua haujlwm.
Cov ntaub ntawv hais txog kev nyab xeeb mus sij hawm ntev ntawm S-Adenosyl-L-Methionine raug txwv vim tias cov neeg koom nrog hauv kev tshawb fawb feem ntau coj nws tsuas yog lub sijhawm luv luv xwb.Txawm li cas los xij, hauv ib txoj kev tshawb fawb txog kab mob siab cawv, cov neeg koom siv S-Adenosyl-L-methionine rau 2 xyoos;nyob rau hauv txoj kev tshawb no, tsis muaj kev phiv loj heev.
Cov neeg uas muaj kev puas siab puas ntsws bipolar (ib yam mob uas tshwm sim los ntawm kev xav hloov pauv, los ntawm kev nyuaj siab mus rau mania) yuav tsum tsis txhob noj SAME rau lawv cov tsos mob kev nyuaj siab tshwj tsis yog nyob rau hauv kev saib xyuas ntawm tus kws kho mob vim SAMe tuaj yeem ua rau cov tsos mob ntawm tus mob mania.
Txawm hais tias S-Adenosyl-L-Methionine tau siv los kho cholestasis thaum cev xeeb tub, nws tsis tau tsim muaj kev nyab xeeb thaum cev xeeb tub.
SAMe tuaj yeem txo cov teebmeem ntawm levodopa (L-dopa), uas yog siv los kho tus kab mob Parkinson.Nws kuj tseem muaj peev xwm hais tias SAMe tuaj yeem cuam tshuam nrog cov tshuaj thiab cov khoom noj khoom haus uas nce qib serotonin (ib yam tshuaj uas tsim los ntawm cov paj hlwb), xws li tshuaj tiv thaiv kev nyuaj siab, L-tryptophan, thiab St. John's wort.
Muaj kev txhawj xeeb txog kev siv SAMe los ntawm cov neeg uas muaj kev tiv thaiv kab mob (xws li cov neeg uas muaj tus kab mob HIV).Immunocompromised cov neeg muaj kev pheej hmoo rau Pneumocystis carinii kab mob, thiab SAMe txhim kho txoj kev loj hlob ntawm cov kab mob no.
Kev mob tshwm sim ntawm SAMe tsis tshua muaj tshwm sim, thiab thaum lawv tshwm sim lawv feem ntau muaj teeb meem me xws li xeev siab lossis plab zom mov.
-
D-Methionine CAS 348-67-4 (HD-Met-OH) Assay 99...
-
L-Methionine CAS 63-68-3 (H-Met-OH) Kev Ntsuas 99.0 ~ ...
-
DL-Methionine CAS 59-51-8 (H-DL-Met-OH) Kev Ntsuam Xyuas 9...
-
Fmoc-Met-OH CAS 71989-28-1 Fmoc-L-Methionine Pu...
-
H-Met-Ome · HCl CAS 2491-18-1 L-Methionine Methyl...
-
N-Acetyl-L-Methionine CAS 65-82-7 (Ac-Met-OH; N...
-
S-Adenosyl-L-Methionine (Ademetionine; SAMe) CA...