Afatinib Dimaleate Intermediate CAS 314771-88-5 Purity > 99.0% (HPLC) Hoobkas

Lus piav qhia luv luv:

Lub npe tshuaj: (S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-Amine

CAS: 314771-88-5 Nr

Purity:> 99.0% (HPLC)

Cov tsos mob: daj mus rau lub teeb daj hmoov

Intermediate of Afatinib Dimaleate (CAS: 850140-73-7)

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Product Detail

Yam khoom

Khoom cim npe

Nqe lus piav qhia:

Ruifu Chemical Supply Intermediates ntawm Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
Tom ntej: Dimethylamino Acetaldehyde Diethyl Acetal CAS 3616-56-6
Tom ntej: Trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-ib CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineCAS Nr .: 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineCAS Nr .: 314771-88-5

Chemical Properties:

Tshuaj npe	(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-Amine
Synonyms	N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-[(3S)-oxolan-3-yl]oxyquinazolin-4-Amine;7-((S)-Tetrahydrofuran-3-yloxy)-4-(3-Chloro-4-Fluorophenyl)amino-6-Nitroquinazoline;Afatinib impurity
CAS Nr	314771-88-5
CAT Number	Qauv TSIS MUAJ: RF-PI2027
Tshuag xwm txheej	Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons
Molecular Formula	C18H14ClFN4O4
Molecular Luj	404.78 ib
Qhov ntom	1.534 ± 0.060 g / cm3
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Yellow to Light Yellow Powder
Purity / Analysis Method	> 99.0% (HPLC)
Poob rau ziab	<0.50%
Tus kheej impurity	<0.50%
Tag nrho cov impurities	<1.00%
Hnyav Hlau	≤ 20ppm
Test Standard	Enterprise Standard
Kev siv	Intermediate of Afatinib Dimaleate (CAS: 850140-73-7)

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo

Qhov zoo:

FAQ:

Daim ntawv thov:

(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-Amine (CAS: 314771-88-5) Kev npaj ntawm Afatinib Dimaleate (CAS: 850140-73-7).Afatinib yog lub hom phiaj tshuaj tiv thaiv kab mob qog noj ntshav tshiab, lub cim tshiab ntawm cov tshuaj tiv thaiv qhov ncauj, lub ntiaj teb thawj cov tshuaj tiv thaiv kab mob qog noj ntshav uas cuam tshuam tsis zoo rau tsev neeg ErbB, thiab muaj txiaj ntsig zoo dua thiab tiv thaiv cov teeb liab uas ua rau muaj kev loj hlob ntawm cov qog nqaij hlav cancer. , txo lossis ncua kev loj hlob ntawm cov qog nqaij hlav cancer.Afatinib belongs rau ib chav kawm ntawm cov tshuaj hu ua tyrosine kinase inhibitors.Nws ua haujlwm los ntawm kev thaiv cov kev ua haujlwm ntawm ob qho kev sib raug zoo ntawm cov proteins, epidermal growth factor receptor (EGFR) thiab human epidermal growth factor receptor 2 (HER2).Siv rau thawj kab kev kho mob ntawm cov neeg mob uas muaj metastatic uas tsis yog-me me ntawm lub ntsws cancer.Afatinib yog lub hom phiaj tshuaj tiv thaiv kab mob qog noj ntshav tshiab, lub cim tshiab ntawm cov tshuaj tiv thaiv qhov ncauj, lub ntiaj teb thawj cov tshuaj tiv thaiv kab mob qog noj ntshav uas cuam tshuam tsis zoo rau tsev neeg ErbB, thiab muaj txiaj ntsig zoo dua thiab tiv thaiv cov teeb liab uas ua rau muaj kev loj hlob ntawm cov qog nqaij hlav cancer. , txo lossis ncua kev loj hlob ntawm cov qog nqaij hlav cancer.