Anastrozole CAS 120511-73-1 API Hoobkas High Quality Featured duab

Anastrozole CAS 120511-73-1 API Hoobkas Zoo

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Lub npe: Anastrozole

CAS: 120511-73-1 Nr

Cov tsos mob: Dawb rau Off-White Crystalline Hmoov

Kev Ntsuas: 98.0% ~ 102.0%

AnastrozoleKev kho mob cancer mis

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Lub npe tshuaj: Anastrozole
CAS: 120511-73-1 Nr

Chemical Properties:

Lub npe	Anastrozole
Synonyms	Arimidex;α, α, α', α'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl) -1,3-benzenediacetonitrile
CAS Nr	120511-73-1
CAT Number	Tus Qauv Zauv: RF-API74
Tshuag xwm txheej	Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms
Molecular Formula	C17H19N5
Molecular Luj	293.37 Nws
Solubility	Soluble hauv DMSO thiab Ethanol
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Dawb rau Off-White Crystalline Hmoov
Kev Taw Qhia A	IR/MS Ua raws li tus qauv siv
Kev Qhia B	HPLC thiab peak shape: Sib haum rau siv
Melting Point	81.0 ~ 84.0 ℃
Cov ntsiab lus dej (los ntawm KF)	≤ 0.30%
Residue ntawm Ignition	≤0.10%
Poob rau ziab	≤0.50%
Hnyav Hlau	≤10ppm
Yam khoom muaj feem
impurity A	≤0.10%
Impurity B	≤ 0.20%
Cov impurity C	≤ 0.20%
Impurity D	≤0.10%
Impurity E	≤0.10%
Ib leeg Lwm yam Impurity	≤0.10%
Tag nrho cov impurities	≤0.50%
Residual Solvents
Cyclhexane	≤ 0.30%
Ethyl Acetate	≤0.50%
Assay	98.0% ~ 102.0% (ntawm lub hauv paus qhuav)
Txee lub neej	24 Lub Hlis
Test Standard	Enterprise Standard;Teb Chaws Asmeskas Pharmacopoeia (USP) Standard
Kev siv	Kev kho mob cancer mis

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.

Qhov zoo:

FAQ:

Daim ntawv thov:

Anastrozole (CAS 120511-73-1), yog non-steroidal, thib peb tiam achiral triazole derivative ua lag luam raws li ARIMIDEX® los ntawm AstraZeneca Pharmaceuticals LP1.Nws yog ib qho ntawm peb tiam aromatase inhibitor uas yog ib qho kev sib tw thiab xaiv inhibitor ntawm aromatase, yog li thaiv kev hloov pauv ntawm testosterone rau hauv estradiol thiab androstenedione rau hauv estrone.Inhibition ntawm aromatase enzyme tshwm sim tshwj xeeb los ntawm kev sib tw khi ntawm aromatase rau hemegroup ntawm cytochrome P450, txo cov tshuaj estrogen biosynthesis nyob rau hauv cov ntaub so ntswg peripheral ntawm lub cev thiab hauv lub mis.

Anastrozole yog ib qho kev kho mob zoo rau kev mob qog noj ntshav thaum ntxov.Zoo li lwm yam aromatase inhibitors, nws cov txiaj ntsig tseem ceeb tshaj plaws yog kev pheej hmoo ntawm cov pob txha tawg, uas rau anastrozole tau txwv rau lub sijhawm kho.Nws tus yam ntxwv muaj mob me me thaum piv nrog cov tshuaj kho mob;Txawm li cas los xij, nws tau pom tias ntau tus neeg mob kho nrog anastrozole tau yws txog cov tsos mob sib koom ua ke ntau dua li qhov xav tau, tshwj xeeb tshaj yog cov tawv nqaij zoo ib yam li cov mob rheumatoid.Qee qhov kev sim tshuaj anastrozole rau cov poj niam postmenopausal nrog mob qog noj ntshav hauv Tebchaws Europe thiab Tebchaws Meskas tau tshaj tawm cov kabmob musculoskeletal uas yog cov xwm txheej tsis zoo.Anastrozole (Arimidex®) yog ib qho aromatase inhibitor pom zoo nyob rau hauv EU, Tebchaws Asmeskas thiab lwm lub tebchaws thoob ntiaj teb siv los ua kev kho mob ntxiv rau cov poj niam postmenopausal nrog rau theem pib, cov tshuaj hormone receptor-zoo mob cancer mis.Nws kuj tau pom zoo hauv EU thiab lwm lub tebchaws thoob ntiaj teb rau kev kho mob ntxiv rau cov poj niam uas twb muaj 2-3 xyoos ntawm kev kho mob tamoxifen rau mob qog noj ntshav.