Apixaban CAS 503612-47-3 Purity ≥99.5% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom ntawm Apixaban (CAS: 503612-47-3) nrog cov khoom zoo.Ruifu Chemical tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, kev pabcuam zoo heev, me me thiab ntau ntau muaj.Yuav Apixaban,Please contact: alvin@ruifuchem.com
| Tshuaj npe | Apixaban |
| Synonyms | 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine 3-carboxamide, 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3, 4-c]pyridine-3-carboxamide BMS 562247 BMS-562247 |
| Tshuag xwm txheej | Hauv Tshuag, Kev Lag Luam Ntau Lawm |
| CAS Nr | 503612-47-3 |
| Molecular Formula | C25H25N5O4 |
| Molecular Luj | 459.51 g / mol |
| Melting Point | 235.0 ~ 238.0 ℃ |
| Qhov ntom | 1.42 ib |
| COA & MSDS | Muaj |
| Keeb kwm | Shanghai, Suav |
| Qeb | API |
| Hom | Ruifu Tshuaj |
| Cov khoom | Kev soj ntsuam Standards | Cov txiaj ntsig |
| Qhov tshwm sim | Dawb rau Off-White Crystalline Hmoov | Ua raws |
| Poob rau ziab | ≤0.50% | 0.10% |
| Residue ntawm Ignition | ≤0.10% | 0.08% |
| Heavy Metals (raws li Pb) | ≤ 20ppm | Ua raws |
| Yam khoom muaj feem | ||
| Ib qho Impurity | ≤0.50% | Ua raws |
| Tag nrho cov impurities | ≤0.50% | Ua raws |
| Purity / Analysis Method | ≥99.5% (HPLC) | 99.9% |
| Infrared Spectrum | Raws li tus qauv | Ua raws |
| 1 H NMR Spectrum | Raws li tus qauv | Ua raws |
| Xaus | Cov khoom tau raug kuaj & ua raws li cov specifications | |
Pob:Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws lub thawv kaw kom nruj thiab khaws cia rau hauv qhov chaw txias, qhuav (2 ~ 8 ℃) thiab lub tsev tso cua txias kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Shipping:Xa mus thoob ntiaj teb los ntawm huab cua, los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.
Tsis muaj ib qho ntawm cov khoom yuav raug xa mus rau cov teb chaws uas qhov no tuaj yeem cuam tshuam nrog cov patents uas twb muaj lawm.Txawm li cas los xij lub luag haujlwm kawg yog nyob nrog tus neeg yuav khoom.
Rau kev tshawb fawb siv tsuas yog siv rau kev lag luam, tsis yog siv rau tib neeg lossis kev kuaj mob.
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
Apixaban (CAS: 503612-47-3) yog ib daim ntawv tshiab ntawm cov tshuaj anticoagulant ntawm qhov ncauj tsim los ntawm Bristol Myers Squibb thiab Pfizer.Nws yog ib daim ntawv tshiab ntawm qhov ncauj Xa factor inhibitor, thiab nws lub npe lag luam yog Eliquis.Apixaban yog siv los kho cov neeg laus cov neeg laus uas tau xaiv lub duav lossis lub hauv caug hloov phais kom tiv thaiv venous thromboembolism (VTE)
Apixaban (CAS: 503612-47-3) yog ib qho kev xaiv ntawm qhov ncauj qhib Xa factor inhibitor thiab tuaj yeem tiv thaiv thrombin tiam thiab thrombosis.
Apixaban (CAS: 503612-47-3) yog tus thib peb tshiab qhov ncauj anticoagulant mus muag, tom qab dabigatran thiab rivaroxaban, thiab nws twb tau pom zoo nyob rau hauv teb chaws Europe rau kev tiv thaiv venous thromboembolism nyob rau hauv cov neeg mob nyob rau hauv kev xaiv ntawm lub duav los yog lub hauv caug hloov phais.Tawm ntawm peb lub qhov ncauj anticoagulants tau pom zoo nyob rau hauv Tebchaws Europe, piv rau cov qauv kev tiv thaiv tam sim no tiv thaiv venous thromboembolism, enoxaparin, rivaroxaban ua tau zoo hauv cov ntaub ntawv kev sim, thiab apixaban ua tau zoo hauv kev sim ua ntej.Rivaroxaban cov tshuaj kho tau zoo dua me ntsis, tab sis nws ua rau los ntshav ntau dua li apixaban.Cov kws tshawb fawb tau suav tias qhov sib txawv no rau lub sijhawm siv tshuaj, raws li rivaroxaban tau noj 6-8 teev tom qab kev phais hauv cov ntaub ntawv sim, thaum apixaban tau siv 18 teev tom qab kev phais hauv qhov kev sim ua ntej.Cov tshuaj no muaj cov nyhuv curative zoo dua thaum siv los ze zog rau lub sijhawm ntawm kev phais, tab sis kuj muaj kev pheej hmoo los ntshav ntxiv.Kev tshawb fawb soj ntsuam pom tau hais tias piv rau kev txhaj tshuaj subdermal txhua hnub ntawm 40mg enoxaparin, 2 qhov ncauj 2.5mg koob tshuaj ntawm apixaban muaj kev tiv thaiv zoo dua tiv thaiv venous thromboembolism tom qab lub duav lossis lub hauv caug hloov pauv thiab tsis ua rau muaj kev pheej hmoo los ntshav.
Apixaban (CAS: 503612-47-3) yog ib hom tshiab ntawm qhov ncauj Xa factor inhibitor ua ke tsim los ntawm Bristol-Myers Squibb thiab Pfizer.Lub npe lag luam yog Eratol, uas yog hom tshiab ntawm qhov ncauj anticoagulant.Los ntawm inhibiting ib qho tseem ceeb coagulation factor Xa, apixaban tuaj yeem tiv thaiv kev tsim cov thrombin thiab thrombosis.Thaum Lub Plaub Hlis 26, 2007, Bristol-Myers Squibb tau koom tes nrog Pfizer los tshaj tawm kev koom tes hauv kev tsim kho qhov ncauj tshiab anticoagulant apixaban uas yog Bristol-Myers Squibb raws li kev hloov kho dua tshiab rau warfarin.Raws li daim ntawv cog lus kev koom tes, Pfizer yuav them nyiaj ua ntej US $ 0.25 nphom rau Bristol-Myers Squibb kom them 60% ntawm tag nrho cov nqi tsim kho ntawm anticoagulant apixaban (yuav tsum tau ua txij lub Ib Hlis 1, 2007), thaum Bristol-Myers Squibb yuav dais qhov seem 40%, yog li tau txais txoj cai los koom ua ke tsim thiab muag cov tshuaj.Nyob rau lub Tsib Hlis 2011, apixaban yog thawj zaug pom zoo rau kev tiv thaiv ntawm venous thrombosis nyob rau hauv cov neeg laus cov neeg laus uas tau xaiv lub duav los yog lub hauv caug hloov pauv nyob rau hauv 27 EU lub teb chaws, Iceland thiab Norway.Thaum Lub Kaum Ib Hlis 20, 2012, European Commission tau pom zoo Ererto (apixaban) rau kev tiv thaiv kev mob stroke thiab cov kab mob embolism hauv cov neeg laus uas tsis yog-valvular atrial fibrillation (NVAF) nrog rau ib lossis ntau qhov kev pheej hmoo.Tom qab ntawd, Canadian Food and Drug Administration, Nyiv, thiab US FDA pom zoo Ererto?(apixaban) rau kev tiv thaiv kab mob stroke thiab systemic embolism nyob rau hauv cov neeg laus cov neeg mob uas tsis yog-valvular atrial fibrillation (NVAF) nrog ib los yog ntau tshaj qhov muaj feem yuav.Thaum lub Plaub Hlis 12, 2013, cov tshuaj tiv thaiv kab mob tshiab Eloto (ELIQUIS) (apixaban) sib koom ua ke tsim los ntawm Bristol-Myers Squibb thiab Pfizer tau tshaj tawm tias muaj npe nyob hauv Suav teb.Ererto yog ib qho tshiab ntawm qhov ncauj Xa inhibitor rau kev tiv thaiv ntawm venous thromboembolism (VTE) hauv cov neeg laus cov neeg mob uas tau xaiv lub duav lossis lub hauv caug hloov.Nws cov npe muab cov kev xaiv tshiab muaj kev nyab xeeb thiab muaj txiaj ntsig zoo rau kev kho mob anticoagulation tom qab phais orthopedic, thiab coj xov xwm zoo rau cov neeg mob Suav uas tab tom hloov lub duav / hauv caug xaiv.Cov kev tshawb fawb soj ntsuam tau lees paub tias piv nrog 40mg enoxaparin ib hnub ib zaug, 2 zaug hauv ib hnub kev tswj hwm qhov ncauj ntawm Eratol?(apixaban) 2.5mg yog qhov zoo dua rau kev tiv thaiv venous thromboembolism tom qab lub duav lossis lub hauv caug hloov pauv, thiab tsis ua rau muaj kev pheej hmoo los ntshav.Daim duab 1 qhia Elotoapixaban ntsiav tshuaj uas tsim los ntawm Bristol-Myers Squibb thiab Pfizer.
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