Argatroban CAS 74863-84-6 API Hoobkas High Purity Anticoagulant
Chaw tsim tshuaj paus Supply Argatroban Related Intermediates:
Tom ntej: Ethyl (2R,4R)-4-Methyl-2-Piperidinecarboxylate CAS 74892-82-3
N-Nitro-1,2,3,4-tetradehydro Argatroban Ethyl Ester CAS 74874-09-2
Tom ntej: 3-Methyl-8-Quinolinesulphonyl Chloride CAS 74863-82-4
Argatroban Monohydrate CAS 141396-28-3
Tom ntej: Argatroban Anhydrous CAS 74863-84-6
| Tshuaj npe | Argatroban |
| Synonyms | Argatroban Anhydrous |
| CAS Nr | 74863-84-6 |
| CAT Number | RF-API 67 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms |
| Molecular Formula | C23H36N6O5S |
| Molecular Luj | 508.63 ib |
| Melting Point | 188.0 ~ 189.0 ℃ |
| Boiling Point | 801.3ºC ntawm 760 mmHg |
| Qhov ntom | 1.47 g / cm3 |
| Shipping Condition | Shipped nyob rau hauv ambient kub |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Dawb rau Off-White Crystalline Hmoov |
| Kev txheeb xyuas HPLC | Lub sijhawm khaws cia ntawm lub hauv paus ntsiab lus siab tshaj plaws tau txais los ntawm Kev Ntsuas Kev Ntsuas raws li qhov tau txais los ntawm Standard tov, raws li kev xeem hauv Assay |
| Identification IR | Ua raws li IR Spectrum ntawm AG RS |
| Identification UV | Nyob rau hauv 259nm thiab 332nm qhov chaw wavelength yuav tsum muaj qhov nqus siab tshaj plaws |
| Dej | 2.5-4.5% |
| Kev daws xim & Clarity | Kev daws yuav tsum yog xim ntshiab |
| Hais txog Tshuaj | |
| Impurity A + Impurity H | ≤0.10% |
| Impurity B | ≤0.10% |
| C + Impurity E | ≤0.10% |
| Impurity D | ≤0.10% |
| Impurity I | ≤0.10% |
| Bach ntawm Unspecified Impurity | ≤0.10% |
| Tag nrho cov impurities | ≤ 0.30% |
| Residual Solvents | |
| Methanol | ≤3000ppm |
| Ethanol | ≤5000ppm |
| Dichloromethane | ≤600ppm |
| Ethyl Acetate | ≤5000ppm |
| Enantiomer (HPLC) | ≤0.10% |
| Isomer Ratio (HPLC) | 30.0% -40.0% |
| Chloride | ≤ 0.01% |
| Residue ntawm Ignition | ≤0.10% |
| Hnyav Hlau | ≤10ppm |
| Cov kab mob endotoxins | <5EU/mg |
| Microbial txwv | TAMC ≤1000 cfu/g |
| Assay | 98.0% -102.0% (raws li anhydrous hauv paus) |
| Test Standard | Enterprise Standard |
| Kev siv | API, Synthetic Antithrombotic Agent Anticoagulant |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard Nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom thiab cov chaw muag khoom ntawm Argatroban (CAS: 74863-84-6) nrog cov khoom zoo, API.
Argatroban (CAS: 74863-84-6) yog ib tug tshiab hluavtaws antithrombotic tus neeg sawv cev pab nyob rau hauv kev saib xyuas anticoagulation lawv ischemic stroke thiab disseminated intravascular coagulation.Nws yog ib qho anticoagulant uas yog ib qho me me direct thrombin inhibitor.Xyoo 2000, argatroban tau ntawv tso cai los ntawm Food and Drug Administration (FDA) rau kev tiv thaiv lossis kev kho mob thrombosis hauv cov neeg mob uas muaj heparin-induced thrombocytopenia (HIT).Nyob rau hauv 2002, nws tau pom zoo siv thaum lub sij hawm percutaneous coronary intervention nyob rau hauv cov neeg mob uas muaj HIT los yog muaj kev pheej hmoo rau tsim nws.Hauv xyoo 2012, nws tau pom zoo los ntawm MHRA hauv UK rau kev tiv thaiv coagulation hauv cov neeg mob uas muaj heparin-induced thrombocytopenia Type II (HIT) uas xav tau kev kho parenteral antithrombotic.
