Aripiprazole Intermediate CAS 129722-34-5 Purity > 98.0% (HPLC)
Chaw tsim tshuaj paus Supply Intermediates ntawm Aripiprazole Nrog High Purity
Aripiprazole API CAS 129722-12-9
Tom ntej: 1-(2,3-Dichlorophenyl) Piperazine Hydrochloride CAS 119532-26-2
7-Hydroxy-3,4-Dihydro-2(1H)-Quinolinone CAS 22246-18-0
7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone CAS 129722-34-5
| Tshuaj npe | 7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone |
| Synonyms | 7-(4-Bromobutoxy)-3,4-Dihydroquinolin-2(1H)-ib;7-(4-Bromobutoxy) -1,2,3,4-Tetrahydro-2-Oxoquinoline;3,4-Dihydro-7-(4-Bromobutoxy)-2(1H)-Quinolinone;Aripiprazole impurity 3 |
| CAS Nr | 129722-34-5 |
| CAT Number | Qauv TSIS MUAJ: RF-PI2269 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
| Molecular Formula | C13H16BrNO2 |
| Molecular Luj | 298.18 Nws |
| Qhov ntom | 1.383 g / cm3 |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Dawb los yog daj daj Crystal hmoov |
| Purity / Analysis Method | > 98.0% (HPLC) |
| Melting Point | 110.0 ~ 114.0 ℃ |
| Poob rau ziab | <1.00% |
| Residue ntawm Ignition | <0.50% |
| Heavy Metals (raws li Pb) | ≤ 20ppm |
| Proton NMR Spectrum | Raws li tus qauv |
| Test Standard | Enterprise Standard |
| Kev siv | Intermediate of Aripiprazole (CAS: 129722-12-9) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone (CAS: 129722-34-5) yog ib qho nruab nrab hauv kev sib txuas ntawm Aripiprazole (CAS: 129722-12-9).Ib qho khoom degradation hauv Aripiprazole ntsiav tshuaj.Aripiprazole (Abilify).Qhov tshiab tshaj plaws, longactingaripiprazole (ib qho arylpiperazine quinolinone derivative), zoo li yog ib feem ntawm agonist ntawm D2 receptors (ie, nws txhawb nqa qee qhov D2 receptors thaum thaiv lwm tus nyob ntawm lawv qhov chaw nyob hauv lub hlwb thiab cov tshuaj concentration).Bioavailability ntawm Aripiprazole yog nyob ib ncig ntawm 87%, nrog lub siab tshaj plaws plasma concentration ntawm 3 mus rau 5 teev tom qab noj.Nws yog metabolized los ntawm dehydrogenation, oxidative hydroxylation, thiab N-dealkylation, loj kho los ntawm hepatic CYPs 3A4 thiab 2D6.Rau kev kho mob ntawm schizophrenia thiab lwm yam kev puas siab puas ntsws.Ib qho kev xaiv dopamine D2-receptor antagonist nrog dopamine autoreceptor agonist kev ua haujlwm.Antipsychotic.
