Atazanavir CAS 198904-31-3 Purity ≥99.0% API Hoobkas Anti-HIV HIV-1 Protease Inhibitor
Muab khoom nrog High Purity thiab ruaj khov zoo
Lub npe tshuaj: Atazanavir
CAS: 198904-31-3 Nr
HIV-1 Protease Inhibitor
API High Quality, Commercial Production
Tshuaj npe | Atazanavir |
Synonyms | BMS-232632 |
CAS Nr | 198904-31-3 |
CAT Number | RF-API 70 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms |
Molecular Formula | C38H52N6O7 |
Molecular Luj | 704.86 ib |
Melting Point | 207.0 ~ 209.0 ℃ |
Solubility | Soluble hauv DMSO;Insoluble hauv dej |
Kev Cia Lub Sij Hawm Ntev | Khaws lub sijhawm ntev ntawm -20 ℃ |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb hmoov |
Daim ntawv | Dawb Base |
Poob rau ziab | ≤0.50% |
Residue ntawm Ignition | ≤ 0.20% |
Hnyav Hlau | ≤ 20ppm |
impurity A | ≤0.10% |
Impurity B | ≤0.10% |
Ib leeg Impurity | ≤ 0.20% |
Tag nrho cov impurities | ≤ 1.0% |
Purity/Kev Ntsuam Xyuas | ≥99.0% (HPLC) |
pH | 5.0 ~ 8.0 |
Test Standard | Enterprise Standard |
Kev siv | HIV-1 Protease Inhibitor Kev Tiv Thaiv Kab Mob HIV |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard Nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
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Atazanavir (CAS 198904-31-3) yog ib qho tshuaj tua kab mob, tshiab thiab muaj zog azapeptide tshuaj ntawm cov tshuaj tiv thaiv protease (PI) chav kawm.Nws yog muag raws li lub npe lag luam Reyataz.Zoo li lwm yam tshuaj tiv thaiv kab mob, nws yog siv los kho tus kab mob ntawm tib neeg lub cev tiv thaiv kab mob hom 1 (HIV-1) protease enzyme nrog inhibition tas li Ki ntawm 66 nmol / L thiab tseem inhibits tus kab mob sib kis ntawm HIV-1 nrog 50% zoo concentration EC50 xws li. 2.6-5.3 nmol / L.Atazanavir khi rau HIV-1 protease tiv thaiv cov cleavage ntawm gag thiab gag-pol polyproteins, uas ua rau tsim cov virions tsis paub tab nyob rau hauv cov kab mob HIV-1.Atazanavir muaj cov qauv tshuaj sib txawv C-2 sib txawv thiab feem ntau muaj zog tiv thaiv kab mob hauv ntau hom kab mob HIV piv rau lwm cov tshuaj tiv thaiv protease, suav nrog Indinavir, Nelfinavir, Ritonavir, Saquinavir thiab Amprenavir.Atazanavir yog qhov txawv ntawm lwm cov PIs nyob rau hauv uas nws tuaj yeem muab tau ib zaug ib hnub thiab muaj kev cuam tshuam tsawg dua rau tus neeg mob lub lipid profile.Zoo li lwm cov tshuaj tiv thaiv protease, nws tsuas yog siv ua ke nrog lwm cov tshuaj HIV.Atazanavir yog ib qho tshiab azapeptide HIV protease inhibitor.Antiviral.Nws yog noj los ntawm qhov ncauj ib hnub ib zaug.
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