Atazanavir Sulfate CAS 229975-97-7 Purity ≥99.0% API Hoobkas Anti-HIV HIV-1 Protease Inhibitor
Muab khoom nrog High Purity thiab ruaj khov zoo
Lub npe tshuaj: Atazanavir Sulfate
CAS: 229975-97-7 Nr
HIV-1 Protease Inhibitor
API High Quality, Commercial Production
Tshuaj npe | Atazanavir Sulfate |
Synonyms | BMS-232632 sulfate |
CAS Nr | 229975-97-7 |
CAT Number | RF-API 71 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms |
Molecular Formula | C38H52N6O7.H2SO4 |
Molecular Luj | 802.93 ib |
Melting Point | 195.0 ~ 198.0 ℃ |
Solubility | Insoluble hauv dej, Soluble hauv DMSO |
Kev Cia Lub Sij Hawm Ntev | Khaws lub sijhawm ntev ntawm -20 ℃ |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb los yog Off-White hmoov |
Sulfate | 12.0 ~ 12.5% |
Poob rau ziab | ≤0.50% |
Residue ntawm Ignition | ≤0.10% |
Hnyav Hlau | ≤ 20ppm |
Ib leeg Impurity | ≤ 0.30% |
Tag nrho cov impurities | ≤ 1.0% |
Purity/Kev Ntsuam Xyuas | ≥99.0% (HPLC) |
pH | 5.0 ~ 8.0 |
Test Standard | Enterprise Standard |
Kev siv | HIV-1 Protease Inhibitor Kev Tiv Thaiv Kab Mob HIV |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard Nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
Atazanavir Sulfate (BMS-232632 Sulfate) (CAS: 229975-97-7) yog sulfate ntsev daim ntawv ntawm atazanavir uas yog ib qho kev xaiv HIV-1 protease inhibitor, yog thawj protease inhibitor pom zoo rau kev tswj hwm ib hnub.Atazanavir Sulfate yog ib qho substrate thiab inhibitor ntawm CYP3A4, thiab inhibitor thiab inducer ntawm P-glycoprotein (P-gp).Atazanavir Sulfate kuj yog SARS-CoV 3CLpro inhibitor nrog IC50 ntawm 3.49 μM.Atazanavir Sulfate yog ib qho azapeptide thiab HIV-protease inhibitor uas yog siv los kho cov kab mob HIV thiab AIDS nrog rau lwm cov tshuaj tiv thaiv HIV, tau tsim thiab tsim los ntawm Bristol-Myers Squibb (BMS), raws li daim ntawv tso cai thoob ntiaj teb los ntawm Novartis, rau kev kho tus kab mob HIV.Atazanavir tau tsim tawm hauv Asmeskas raws li Reyataz™ thaum Lub Xya Hli 2003. Antiviral.Atazanavir tau pom tias feem ntau muaj zog dua li tsib qhov tam sim no pom zoo HIV-1 protease inhibitors.Atazanavir xaiv inhibits tus kab mob tshwj xeeb ua cov kab mob Gag thiab Gag-Pol polyproteins hauv cov kab mob HIV-1 los ntawm kev khi rau qhov chaw nquag ntawm HIV-1 protease, yog li tiv thaiv kev tsim ntawm virions paub tab.Atazanavir tsis nquag tawm tsam HIV-2.