Azilsartan CAS 147403-03-0 Purity > 99.5% (HPLC) API Hoobkas
Chaw tsim khoom, siab purity, coj mus muag ntau lawm
Tshuaj npe | Azilsartan |
Synonyms | 2-Ethoxy-1-[[2'-(4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-Carboxylic acid |
CAS Nr | 147403-03-0 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C25H20N4O5 |
Molecular Luj | 456.46 ib |
Melting Point | 188 ℃ (txog.) |
Qhov ntom | 1.42 ib |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb los yog Off-White Crystalline Hmoov |
Kev txheeb xyuas | Ua raws li Reference Standard |
Solubility | Xyaum Insoluble hauv dej, me ntsis soluble hauv Ethanol |
Purity / Analysis Method | > 99.5% (HPLC) |
Poob rau ziab | <0.50% |
Residue ntawm Ignition | <0.20% |
Hnyav Hlau | <10ppm |
Yam khoom muaj feem | |
impurity A | <0.15% |
Impurity B | <0.10% |
Cov impurity C | <0.10% |
Lwm yam Unknown Loj tshaj ib leeg impurity | <0.10% |
Tag nrho cov impurities | <0.50% |
Residual Solvents | |
Dichloromethane | <0.06% |
Acetone | <0.50% |
Ethyl Acetate | <0.50% |
Methanol | <0.30% |
Test Standard | Enterprise Standard |
Kev siv | API |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
Azilsartan (CAS: 147403-03-0) yog angiotensin II receptor antagonist tshuaj nyob rau hauv kev txhim kho rau kev kho mob ntshav siab, uas feem ntau yog siv rau kev kho mob ntshav siab.Nws tseem yog tib qho tshuaj angiotensin II receptor antagonist (sartan class) tshuaj nyob rau theem kho mob siab heev tam sim no.Azilsartan thiab Chlorthalidone ua ke yog siv los kho cov ntshav siab (hypertension).Azilsartan yog angiotensin II receptor blocker (ARB).Nws ua haujlwm los ntawm kev thaiv cov khoom hauv lub cev uas ua rau cov hlab ntsha kom nruj.Yog li ntawd, azilsartan relaxes cov hlab ntsha.Qhov no txo qis ntshav siab thiab ua kom cov ntshav thiab oxygen mus rau lub plawv.Azilsartan tau pom zoo thiab tsim tawm hauv Nyij Pooj rau kev kho mob ntawm arterial hypertension nyob rau lub Tsib Hlis 2012. Azilsartan, uas yog ua lag luam raws li lub npe lag luam Azilva.