Bacitracin Zinc CAS 1405-89-6 Potency ≥70 IU/mg Peptide Antibiotic Hoobkas
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom thiab cov chaw muag khoom ntawm Bacitracin Zinc (Zinc Bacitracin) (CAS: 1405-89-6) nrog cov khoom zoo.Peb tuaj yeem muab COA, xa khoom thoob ntiaj teb, me me thiab ntau ntau.Yog tias koj txaus siab rau Bacitracin Zinc (Zinc Bacitracin),Please contact: alvin@ruifuchem.com
| Tshuaj npe | Bacitracin Zinc |
| Synonyms | Bacitracin Zinc ntsev;Zinc Bacitracin |
| Tshuag xwm txheej | Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 10 Tons ib xyoos |
| CAS Nr | 1405-89-6 : kuv |
| Molecular Formula | C66H101N17O16SZn |
| Molecular Luj | 1486.07 Nws |
| Melting Point | 250 ℃ (txog) |
| Dej Solubility | 5.1 g / L |
| COA & MSDS | Muaj |
| Qauv | Muaj |
| Hom | Ruifu Tshuaj |
| Cov khoom | Specifications | Cov txiaj ntsig |
| Qhov tshwm sim | Dawb los yog Lub Teeb Yellow-Grey lossis Beige Hmoov | Ua raws |
| Kev txheeb xyuas | Ua raws li Cov Kev Xav Tau | Pom qhov zoo tshwm sim |
| pH | 6.0 ~ 7.5 hli | 7.1 |
| Poob rau ziab | ≤ 5.0% | 2.7% |
| Zinc (Dried Khoom) | 4.0% ~ 6.0% | 4.20% |
| Peev xwm | ≥70 IU/mg Microbial Assay (Dried Basis) | 71 IU/mg |
| Cov ntsiab lus ntawm Bacitracin A | ≥40.0% | 58.2% |
| Cov ntsiab lus ntawm Active Bacitracin | ≥70.0% (Bacitracin A, B1, B2, thiab B3) | 86.1% |
| Kev txwv ntawm Early Eluting Peptides | ≤ 20.0% | 7.6% |
| Kev txwv ntawm Bacitracin F | ≤ 6.0% | 1.1% |
| Total Viable Aerobic Count | <100 CFU/gram | Ua raws |
| Xaus | Cov khoom ua raws li USP44 Standards | |
| Kev siv tseem ceeb | Peptide Tshuaj tua kab mob | |
Pob:Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws lub thawv kaw kom nruj thiab khaws cia rau hauv qhov chaw txias, qhuav (2 ~ 8 ℃) thiab lub tsev tso cua txias kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Shipping:Xa mus thoob ntiaj teb los ntawm huab cua, los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.
Bacitracin, zinc complex.
Bacitracins zinc complex [1405-89-6].
» Bacitracin Zinc yog zinc complex ntawm bacitracin, uas muaj kev sib xyaw ntawm cov tshuaj tua kab mob polypeptides, cov khoom tseem ceeb yog bacitracins A, B1, B2, thiab B3.Nws muaj lub zog ntawm tsis pub tsawg tshaj 65 Bacitracin Units ib mg, suav nrog lub hauv paus qhuav.Nws muaj tsis tsawg tshaj li 4.0 feem pua thiab tsis ntau tshaj 6.0 feem pua ntawm zinc (Zn), xam nyob rau hauv qhuav.
Ntim thiab khaws cia - Khaws rau hauv cov thawv nruj, thiab khaws cia rau hauv qhov chaw txias.
Labeling-Label nws qhia tias nws yuav tsum tau siv nyob rau hauv kev tsim cov tshuaj nonparenteral nkaus xwb.Qhov twg nws tau ntim rau cov ntawv sau tshuaj, sau nws kom qhia tias nws tsis muaj menyuam yaus thiab tsis tuaj yeem paub tseeb tias lub zog tsis tuaj yeem ntev dua 60 hnub tom qab qhib, thiab hais txog cov naj npawb ntawm Bacitracin Units ib milligram.Qhov twg nws yog npaj los siv rau hauv kev npaj cov tshuaj tsis muaj menyuam, daim ntawv lo hais tias nws tsis muaj menyuam lossis yuav tsum tau ua haujlwm ntxiv thaum lub sijhawm npaj cov ntawv ua kom tsis muaj menyuam.
USP Reference cov qauv <11>-
USP Bacitracin Zinc RS
Kev txheeb xyuas-
A: Thin-Layer Chromatographic Identification Test <201BNP>: ua tau raws li qhov yuav tsum tau ua.
B: Nws ua tau raws li qhov yuav tsum tau ua ntawm cov txheej txheem ua kua chromatographic hauv kev sim rau Kev Sib Sau.
Sterility <71>-Qhov twg daim ntawv lo hais tias nws tsis muaj menyuam, nws ua tau raws li qhov yuav tsum tau ua thaum kuaj raws li qhia rau Membrane Filtration nyob rau hauv Kev Xeem rau Sterility ntawm cov khoom yuav tsum tau kuaj, tshwj tsis yog siv cov kua dej A rau txhua L uas tau ntxiv 20 g ntawm edetate disodium.
pH <791>: nruab nrab ntawm 6.0 thiab 7.5, hauv cov tshuaj (saturated) muaj kwv yees li 100 mg ib mL.
Poob ntawm ziab <731>-Sry txog 100 mg hauv lub raj mis capillary-stoppered hauv lub tshuab nqus tsev ntawm 60 rau 3 teev: nws poob tsis ntau tshaj 5.0% ntawm nws qhov hnyav.
Zinc cov ntsiab lus- [ceeb toom-Cov txheej txheem kev npaj thiab Kev Ntsuas Kev Ntsuas yuav ua kom muaj nuj nqis diluted nrog 0.001 N hydrochloric acid, yog tias tsim nyog, kom tau txais cov kev daws teeb meem ntawm cov ntsiab lus tsim nyog, hloov mus rau cov kab lossis kev ua haujlwm ntawm cov cuab yeej.]
Cov txheej txheem kev npaj-Hloov 3.11 g ntawm zinc oxide, raug hnyav, mus rau 250-mL ntim ntim, ntxiv 80 mL ntawm 1 N hydrochloric acid, sov kom yaj, txias, dilute nrog dej rau ntim, thiab sib tov.Cov tshuaj no muaj 10 mg ntawm zinc ib mL.Ntxiv rau qhov kev daws teeb meem no nrog 0.001 N hydrochloric acid kom tau txais cov txheej txheem npaj muaj 0.5, 1.5, thiab 2.5 µg ntawm zinc ib mL, feem.
Kev sim npaj-Hloov txog 200 mg ntawm Bacitracin Zinc, hnyav hnyav, mus rau 100-mL ntim ntim.Dissolve nyob rau hauv 0.01 N hydrochloric acid, dilute nrog tib yam hnyav rau ntim, thiab sib tov.Pipet 2 mL ntawm cov tshuaj no rau hauv 200-mL volumetric hwj, dilute nrog 0.001 N hydrochloric acid rau ntim, thiab sib tov.
Cov txheej txheem-Concomitantly txiav txim siab absorbances ntawm tus qauv npaj thiab kev xeem npaj ntawm zinc resonance kab ntawm 213.8 nm, nrog ib tug haum atomic absorption spectrophotometer (saib Spectrophotometry thiab Light-scattering <851>), nruab nrog ib tug zinc hollow-cathode teeb thiab Cov nplaim hluav taws xob cua-acetylene, siv 0.001 N hydrochloric acid ua qhov khoob.Npaj cov absorbances ntawm Standard npaj tiv thaiv concentration, nyob rau hauv µg ib mL, zinc, thiab kos cov kab ncaj nraim uas haum rau peb plotted ntsiab lus.Los ntawm daim duab thiaj li tau txais, txiav txim siab qhov concentration, hauv µg ib mL, ntawm zinc hauv Kev Ntsuas Kev Ntsuas.Muab xam cov ntsiab lus ntawm zinc, nyob rau hauv feem pua, nyob rau hauv ib feem ntawm Bacitracin Zinc coj los ntawm cov mis:
1000C / W
nyob rau hauv uas C yog qhov concentration hauv µg ib mL, ntawm zinc nyob rau hauv lub xeem npaj;thiab W yog qhov hnyav, hauv mg, ntawm feem ntawm Bacitracin Zinc noj.
Kev sib xyaw-
Buffer - Dissolve 34.8 g ntawm poov tshuaj phosphate, dibasic, hauv 1 L dej.Kho nrog 27.2 g ntawm poov tshuaj phosphate, monobasic, yaj hauv 1 L dej, mus rau pH ntawm 6.0.
Txawb Phase-Npaj ib qho sib xyaw ntawm methanol, dej, Buffer, thiab acetonitrile (26:15:5:2).Sib tov zoo, thiab degas.
Diluent-Dissolve 40 g ntawm edetate disodium hauv 1 L dej.Kho nrog dilute sodium hydroxide mus rau pH ntawm 7.0.
System suitability solution-Dissolve ib qhov hnyav hnyav npaum li cas ntawm USP Bacitracin Zinc RS hauv Diluent kom tau txais cov tshuaj nrog cov nominal concentration ntawm txog 2.0 mg ib mL.
Tshaj tawm qhov pib daws teeb meem-Dilute kom muaj nuj nqis, nrog dej, ib lub ntim tsim nyog ntawm System suitability tov kom tau txais cov kev daws teeb meem nrog qhov paub txog qhov concentration ntawm 0.01 mg ib mL.
Peak identification solution-Dissolve ib qhov hnyav ntawm USP Bacitracin Zinc RS nyob rau hauv ib lub ntim haum ntawm Diluent kom tau txais ib qho kev daws teeb meem nrog cov nominal concentration ntawm txog 2.0 mg ib mL.Tshav kub hauv dej npau npau rau 30 feeb.Txias rau chav sov.
Test solution-Dissolve ib qho hnyav hnyav ntawm Bacitracin Zinc hauv Diluent kom tau txais cov tshuaj nrog cov nominal concentration ntawm li 2.0 mg ib mL.
Chromatographic system (saib Chromatography <621>)-Cov kua chromatograph yog nruab nrog lub tshuab nqus tsev nqus thiab qhov kawg-capped 4.6- × 250-mm kem uas muaj 5-µm packing L1.Tus nqi ntws yog 1.0 mL ib feeb.Teem lub wavelength ntawm tus ntes ntawm 300 nm.Txhaj li ntawm 100 µL ntawm Peak identification tov, thiab txheeb xyuas qhov chaw ntawm bacitracin F, uas yog qhov paub tsis meej, siv lub sijhawm tuav tus txheeb ze uas tau qhia hauv Table 1.
Table 1
Lub Npe Lub Sijhawm Relative Retention Time (kwv yees)
Bacitracin C1 0.5
Bacitracin C2 0.6
Bacitracin C3 0.6
Bacitracin B1 0.7
Bacitracin B2 0.7
Bacitracin B3 0.8
Bacitracin A 1.0
Bacitracin F 2.4
Hloov lub wavelength ntawm lub ntes thiab teem rau 254 nm.Chromatograph cov kev daws teeb meem tsim nyog, thiab sau cov lus teb ncov raws li qhia rau Kev Ua Haujlwm: txheeb xyuas lub ncov ntawm cov khoom nquag tshaj plaws ntawm bacitracin (bacitracins A, B1, B2 thiab B3), thaum ntxov eluting peptides (cov eluting ua ntej lub ncov vim bacitracin B1. ) thiab cov impurity, bacitracin F, siv cov txheeb ze tuav lub sij hawm muaj nuj nqis muab rau hauv Table 1. Xam cov peak-rau-valley piv siv cov mis:
Hp / HV
nyob rau hauv uas Hp yog qhov siab tshaj lub hauv paus ntawm lub ncov vim bacitracin B1;thiab HV yog qhov siab saum toj ntawm lub hauv paus ntawm qhov qis tshaj ntawm qhov nkhaus sib cais cov bacitracin B1 ncov los ntawm lub ncov vim bacitracin B2.Qhov nruab nrab-rau-kiv qhov piv tsis tsawg dua 1.2.
Cov txheej txheem-Kev txhaj tshuaj sib npaug sib npaug (100 µL) ntawm Diluent, Test solution, thiab Tshaj Qhia qhov pib daws.Sau cov chromatograms li peb zaug ntawm lub sijhawm khaws cia ntawm bacitracin A. Txheeb xyuas cov peaks uas siv cov sij hawm tuav cov txheeb ze uas tau qhia hauv Table 1. Ntsuas cov cheeb tsam ncov ntawm tag nrho cov peaks hauv Test solution.[ceeb toom-Tsis quav ntsej ib qho ncov hauv Kev Ntsuas Kev daws teeb meem uas muaj thaj tsam tsawg dua li thaj tsam ntawm bacitracin A ncov hauv Kev Tshaj Tawm qhov pib daws;disregard tej ncov pom nyob rau hauv Diluent.]
ceeb toom-Tag nrho cov cheeb tsam nyob rau hauv cov nram qab no xam yog txhais raws li cheeb tsam ntawm tag nrho cov peaks tshwj tsis yog lub chaw pib qhia.
Cov ntsiab lus ntawm bacitracin a-Xam cov feem pua ntawm bacitracin A siv cov qauv:
(rA / Tag nrho cheeb tsam) × 100
nyob rau hauv uas rA yog cheeb tsam teb los ntawm bacitracin A. Bacitracin A cov ntsiab lus tsis tsawg tshaj li 40.0% ntawm tag nrho cheeb tsam.
Cov ntsiab lus ntawm active bacitracin-Xam cov feem pua ntawm cov nquag bacitracin (bacitracin A, B1, B2, thiab B3) siv cov mis:
(rA + rB1 + rB2 + rB3 / Total area) × 100
nyob rau hauv uas rA, rB1, rB2, thiab rB3 yog thaj tsam teb los ntawm bacitracin A, B1, B2, thiab B3, feem.Cov txiaj ntsig ntawm bacitracin A, B1, B2, thiab B3 tsis tsawg dua 70.0% ntawm tag nrho cheeb tsam.
txwv tsis pub ntxov eluting peptides-Xam cov feem pua ntawm tag nrho cov peaks eluting ua ntej lub ncov vim bacitracin B1 siv cov mis:
(rPreB1 / Tag nrho cheeb tsam) × 100
nyob rau hauv uas rPreB1 yog cov sum ntawm cov lus teb ntawm tag nrho cov peaks eluting ua ntej lub ncov rau bacitracin B1.Qhov kev txwv ntawm cov eluting peptides thaum ntxov (cov eluting ua ntej lub ncov vim bacitracin B1) tsis ntau tshaj 20.0%.
txwv ntawm bacitracin f- xam qhov feem pua ntawm bacitracin F siv cov mis:
100 × (rF / rA)
nyob rau hauv uas rF yog cov lus teb ntawm bacitracin F los ntawm Test tov;thiab rA yog cov lus teb ntawm bacitracin A los ntawm Test solution.Qhov txwv ntawm bacitracin F, uas paub tsis meej, tsis ntau tshaj 6.0%.
Assay-Proceed with Bacitracin Zinc raws li qhia nyob rau hauv Antibiotics-Microbial Assays 81.
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
Safety Description S22 - Tsis txhob ua pa plua plav.
S24/25 - Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag.
WGK Germany 3
FLUKA BRAND F CODE 3
HS Code 2941909099
Bacitracin yog muab rho tawm los ntawm kab lis kev cai daws ntawm lichen (Bacillus licheniformis) thiab yog polypeptide tshuaj tua kab mob.Dawb los yog lub teeb daj hmoov, tsw ntxhiab los yog me ntsis tsw, iab saj, hygroscopic.Yooj yim soluble hauv dej thiab ethanol, tsis ruaj khov, aqueous tov yog yooj yim inactivated ntawm chav tsev kub, tsis ruaj tsis khov ntawm pH 9, thiab yuav tsum tau muab tso rau hauv tub yees tom qab dissolution.Cov khoom no yog xam raws li cov khoom qhuav, thiab titer ib milligram yuav tsum tsis pub tsawg tshaj 55 bacitracin units.Bacitracin zinc yog bacitracin zinc ntsev, uas ruaj khov dua li bacitracin.Nws yog siv los ua ib qho khoom noj ntxiv thiab muaj lub luag haujlwm ntawm kev txhawb nqa kev loj hlob thiab kev loj hlob ntawm cov tsiaj nyeg thiab nqaij qaib, tiv thaiv kab mob hauv plab, thiab nce kev them nyiaj noj.Cov koob tshuaj yog tib yam li bacitracin.Bacitracin antibacterial spectrum zoo ib yam li penicillin, uas muaj cov tshuaj tua kab mob muaj zog ntawm cov kab mob gram-zoo thiab tsis muaj txiaj ntsig zoo rau cov kab mob gram-tsis zoo.Rau cov kab mob hnyav ntawm cov tshuaj tiv thaiv Staphylococcus aureus.Kev tswj qhov ncauj tsis nqus thiab yog siv rau kev mob plab hnyuv.Kev siv sab nraud kuj tseem siv tau rau lub cev nto, qhov ncauj thiab qhov muag kab mob thiab mastitis tshwm sim los ntawm cov kab mob rhiab heev.Nws muaj kev puas tsuaj rau lub raum.Bacitracin zinc tau siv los ua cov khoom noj khoom haus ntxiv.Kev tswj ntawm qhov ncauj tsis yog absorbed, yog li nws feem ntau ntseeg hais tias tsis muaj tshuaj residue teeb meem nyob rau hauv cov tsiaj txhu thiab nqaij qaib cov khoom.Cov khoom no yog ib tug nqaim-spectrum tshuaj tua kab mob, uas muaj ib tug muaj zog antibacterial nyhuv rau feem ntau gram-zoo kab mob.Nws kuj tseem siv tau rau spirochetes thiab actinomycetes, tab sis nws tsis muaj txiaj ntsig tiv thaiv kab mob gram-tsis zoo.Nws muaj cov nyhuv synergistic nrog ntau yam tshuaj tua kab mob xws li penicillin G, streptomycin, neomycin, polymyxin, thiab lwm yam. Nws cov zinc ntsev feem ntau yog siv los ua cov khoom noj ntxiv, uas muaj cov haujlwm ntawm kev tiv thaiv kab mob hauv plab, txhawb kev loj hlob thiab txhim kho kev noj qab haus huv.Cov kab mob tuaj yeem maj mam txhim kho cov khoom no, tab sis tsis muaj qhov sib txawv ntawm cov khoom no thiab lwm yam tshuaj tua kab mob.Cov khoom no muaj tshuaj lom heev thiab tsis tuaj yeem txhaj tshuaj.Nws tuaj yeem noj qhov ncauj los kho kab mob raws plab hauv cov tsiaj nyeg thiab Treponema dysentery hauv npua.Clinically, nws yog feem ntau siv ua ke nrog ntau yam tshuaj tua kab mob xws li penicillin, streptomycin, neomycin, polymyxin B, thiab lwm yam los txhim kho kev ua tau zoo.
Bacitracin Zinc yog ib qho complex tsim los ntawm bacitracin thiab zinc ions.nws yog ib qho tshuaj tua kab mob polypeptide thiab yog cov tshuaj tua kab mob uas siv ntau tshaj plaws tam sim no.zinc cov ntsiab lus feem ntau yog 2% ~ 12%.Cov khoom siv hluavtaws yog cov hmoov dawb lossis daj daj, nrog cov ntxhiab tsw tshwj xeeb, yooj yim rau yaj rau hauv cov tshuaj tsis muaj zog alkaline, thiab yooj yim soluble hauv dej, methanol thiab ethanol.Bacitracin zinc muaj cov tshuaj tua kab mob muaj zog tiv thaiv kab mob Gram-zoo, thiab tseem muaj cov tshuaj tua kab mob tiv thaiv qee cov kab mob Gram-tsis zoo.Kev siv cov bacitracin zinc hauv npua puv nqi pub tuaj yeem txhawb kev loj hlob, txhim kho kev noj zaub mov zoo, thiab tiv thaiv tus npua kab mob raws plab thiab kab mob ua pa ntev.Qhov sib ntxiv concentration yog feem ntau 10 ~ 100mg / kg, thiab cov nyhuv tsis zoo dua li qhov sib ntxiv.Bacitracin Zinc feem ntau tsis nqus hauv plab hnyuv, yog li tsis muaj teeb meem seem.Nws yog ib qho kev nyab xeeb thiab txhim khu kev qha tshuaj tua kab mob.Bacitracin Zinc yog tshuaj lom heev thiab tsis yooj yim nqus los ntawm txoj hnyuv, yog li nws tsis tuaj yeem siv los ua kev kho mob rau cov kab mob.
Cov tshuaj tua kab mob polypeptide muaj cov tshuaj tua kab mob muaj zog ntawm cov kab mob gram-zoo, thiab tseem muaj cov kab mob tua kab mob ntawm ob peb kab mob gram-negative, spirochetes, actinomycetes thiab txawm penicillin-resistant staphylococci.Cov txheej txheem tiv thaiv kab mob yog txhawm rau txhawm rau tsim cov kab mob ntawm cov kab mob ntawm phab ntsa thiab ua rau cov kab mob ntawm cov kab mob plasma membrane puas.Nws tuaj yeem txhawb kev loj hlob ntawm cov kab mob muaj txiaj ntsig zoo hauv cov hnyuv, ua kom cov permeability ntawm cov hnyuv mucosa, thiab txhawb kev nqus ntawm cov as-ham.Nws yog tsuas yog siv los txhawb kev loj hlob ntawm cov tsiaj nyeg thiab nqaij qaib, tiv thaiv thiab tswj cov kab mob raws plab ntawm cov tsiaj nyeg thiab nqaij qaib thiab cov ntshav dysentery tshwm sim los ntawm Treponema.Bacitracin zinc yog ib qho nyuaj absorbed sab hauv, thiab feem ntau ntawm nws yog excreted nrog quav nyob rau hauv 2 hnub, yog li nws tsis yooj yim rau nyob twj ywm nyob rau hauv cov tsiaj nyeg thiab nqaij qaib khoom;Cov kab mob tsis tshua muaj kev tiv thaiv rau bacitracin, thiab tsis muaj kev sib txuam nrog lwm cov tshuaj tua kab mob, Thiab muaj kev sib koom ua ke nrog penicillin, streptomycin, neomycin, aureomycin, polymyxin, thiab lwm yam. Cov khoom no muaj tshuaj lom heev thiab tsis tuaj yeem txhaj tshuaj.Cov khoom no yog contraindicated nrog olaquindox, kitasamycin, virginiamycin, thiab Enramycin.
Raws li cov khoom noj ntxiv, nws yog siv los txhawb kev loj hlob ntawm cov tsiaj nyeg thiab nqaij qaib, tiv thaiv kab mob raws plab ntawm cov tsiaj nyeg thiab nqaij qaib thiab cov ntshav dysentery tshwm sim los ntawm treponema.Bacitracin zinc tsis yog absorbed sab hauv, thiab feem ntau ntawm nws yog tawm nrog quav hauv 2 hnub, yog li nws tsis yooj yim rau nyob twj ywm hauv cov tsiaj nyeg thiab nqaij qaib;Cov kab mob tsis tshua muaj kev tiv thaiv rau bacitracin, thiab tsis muaj kev sib txuam nrog lwm cov tshuaj tua kab mob, Thiab muaj kev sib koom ua ke nrog penicillin, streptomycin, neomycin, aureomycin, polymyxin, thiab lwm yam. Cov khoom no muaj tshuaj lom heev thiab tsis tuaj yeem txhaj tshuaj.Cov khoom no yog contraindicated nrog olaquindox, kitasamycin, virginiamycin, thiab Enramycin.
Bacitracin Zinc yog tshuaj tua kab mob polypeptide, uas muaj cov kab mob bactericidal ntawm cov kab mob gram-zoo.Nws cov txheej txheem yog tsuas yog inhibit cov kab mob phab ntsa synthesis ntawm cov kab mob, thiab tseem tuaj yeem ua ke nrog cov cell membrane ntawm cov kab mob rhiab heev, ua rau kev ncaj ncees ntawm cov cell membrane, thiab ua rau cov dej ntws tawm ntawm cov khoom tseem ceeb hauv lub cell.Zoo inhibit Gram-positive kab mob thiab qee cov kab mob Gram-negative;tus nqi ntawm cov kab mob tsis kam mus rau bacitracin zinc yog qeeb, thiab tsis muaj kev sib tw nrog lwm cov tshuaj tua kab mob.polypeptide tshuaj tua kab mob inhibit dephosphorylation ntawm lipid pyrophosphate, yog li inhibiting synthesis ntawm cov kab mob cell phab ntsa.
