Betulin CAS 473-98-3 Purity > 99.0% (HPLC) Cog Extract
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom ntawm Betulin (CAS: 473-98-3) nrog cov khoom zoo.Ruifu Chemical tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, me me thiab ntau ntau muaj.Yuav Betulin,Please contact: alvin@ruifuchem.com
| Tshuaj npe | Betulin |
| Synonyms | Betulinol;Betulinic cawv;Betula Camphor;Birch nplooj Extract;Betulol;Trochol;Lup-20(29)-ene-3β,28-diol;(3β)-Lup-20(29)-ene-3,28-diol |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, Commercially Manufactured |
| CAS Nr | 473-98-3 : kuv |
| Molecular Formula | C30H50O2 |
| Molecular Luj | 442.73 g / mol |
| Melting Point | 251.0 ~ 257.0 ℃ |
| Qhov ntom | 1.017g / cm3 |
| Kev sib hloov tshwj xeeb [a]20/D | +17.0° to +21.0° (C = 2 in Pyridine) |
| Kev ruaj ntseg | Hygroscopic |
| Cia Temp. | Qhov chaw txias & qhuav (2 ~ 8 ℃) |
| COA & MSDS | Muaj |
| Qeb | Cog Extracts |
| Hom | Ruifu Tshuaj |
| Cov khoom | Kev soj ntsuam Standards | Cov txiaj ntsig |
| Qhov tshwm sim | Dawb rau Off-White Powder | Dawb hmoov |
| Betulin Purity | > 98.0% (HPLC) | 99.15% |
| Melting Point | 251.0 ~ 257.0 ℃ | Ua raws |
| Poob rau ziab | <2.00% (2g / 105 ℃ / 5 teev) | 0.13% |
| Tshauv | <0.50% (2g / 600 ℃ / 5 teev) | 0.10% |
| Kev ceev ceev | 0.25-0.45 g / ml | Ua raws |
| Particle Loj | 98% Pass 80 Mesh | Ua raws |
| Heavy Metals (Pb) | ≤10ppm | <10ppm |
| Arsenic (As) | ≤1ppm | <1 ppm |
| Residual Solvent | ≤1000ppm | Ua raws |
| Kev ntsuam xyuas microbiological | ||
| Tag Nrho Phaj suav | ≤1000CFU / g | Ua raws |
| Poov & Pwm | ≤100CFU / g | Ua raws |
| Escherichia Coli | Tsis zoo | Tsis zoo |
| Infrared Spectrum | Raws li tus qauv | Ua raws |
| Solubility hauv Pyridine 50mg / ml | Yellow to Brown Clear mus me ntsis hazy | Hla |
| Xaus | Cov khoom tau raug kuaj & ua raws li cov specifications | |
Pob:Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv lub thawv kaw nruj nreem.Khaws rau hauv qhov chaw txias, qhuav (2 ~ 8 ℃) thiab lub tsev tso cua txias kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo thiab kub kub.
Shipping:Xa mus thoob ntiaj teb los ntawm huab cua, los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
Risk Codes
R36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij.
R20/21/22 - Ua phem los ntawm kev nqus pa, tiv tauj nrog daim tawv nqaij thiab yog tias nqos.
R68/20/21/22 -
R68 - Muaj peev xwm ua rau muaj kev cuam tshuam tsis zoo
Kev nyab xeeb piav qhia
S36/37 - Hnav cov khaub ncaws tiv thaiv thiab hnab looj tes tsim nyog.
S36 - Hnav khaub ncaws tiv thaiv zoo.
S26 - Nyob rau hauv rooj plaub ntawm qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
WGK Germany 3
RTECS OK5755000
HS Code 2906199090
Betulin (CAS: 473-98-3) yog ib qho kev rho tawm los ntawm cov tawv ntoo ntawm cov ntoo dawb birch, uas tau paub txij li xyoo pua 18th thiab yog tshuaj txhais tau tias.Betulin tau tshawb pom los ntawm German-Lavxias chemist Johann Tobias Lowitz.Nws yog thawj tus kws tshawb fawb los kawm thiab ua tus yam ntxwv ntawm betulin, thiab hauv kev ua yog ib qho ntawm thawj zaug cais cov khoom siv cog qoob loo.Betulin yog ib yam khoom ntawm cov nroj tsuag ntshiab uas muab cov tawv ntoo birch nws cov xim dawb.Betulin tiv thaiv cov ntoo birch los ntawm ib puag ncig, xws li huab cua kub, kab tsuag kab mob thiab hnub ci hluav taws xob.
Betulin yog dawb crystalline hmoov, soluble hauv cawv, chloroform thiab benzene, me ntsis soluble hauv dej txias, roj av ether.
Physiological teebmeem ntawm betulin
1. Betulin thiab nws cov derivatives tau pom tias muaj peev xwm ua tau zoo li tshuaj lom neeg hauv HIV thiab kev kho mob qog noj ntshav.Lawv ua haujlwm los ntawm kev cuam tshuam nrog cov theem tom ntej ntawm tus kab mob lub neej thiab cuam tshuam nrog tus kab mob nkag mus thiab kev loj hlob thiab kev loj hlob.
2. Cov tshuaj tiv thaiv qog nqaij hlav zoo, uas ncaj qha ua rau qee hom qog nqaij hlav los pib cov kev pab cuam apoptosis tus kheej, thiab tuaj yeem ua rau qeeb ntawm ntau hom qog hlwb.
3. Betulin tuaj yeem txo cov kev noj zaub mov vim kev rog rog, txo cov lipid cov ntsiab lus hauv cov ntshav thiab cov ntaub so ntswg, thiab txhim kho hauv-sulin k rhiab heev.
4. Lawv muaj cov tshuaj tiv thaiv mob me me ntawm qhov siab dua, thiab lawv cov khoom tiv thaiv kab mob feem ntau yog los ntawm inhibition ntawm cov kab mob uas tsis yog neural.
5. Betulin tuaj yeem cuam tshuam qhov kev loj hlob ntawm sterol regulatory element-binding proteins (SBERPs) hauv vivo, yog li txo cov biosynthesis ntawm cov roj cholesterol thiab fatty acids.
6. Tsis tas li ntawd, Betulin muaj cov tshuaj tiv thaiv kab mob, tiv thaiv kab mob, inhibiting protein dissolution nyob rau hauv cov plaub hau fiber, txhim kho cov luster ntawm cov plaub hau puas, thiab txhawb cov plaub hau kev loj hlob.Betulin tuaj yeem siv rau hauv cov khoom noj, tshuaj pleev ib ce thiab tshuaj lag luam.
Pharmaceutical kev lag luam:
Betulin feem ntau yog siv los ua tshuaj nruab nrab, thiab Betulin thiab nws cov derivatives ua cov tshuaj lom neeg muaj peev xwm ua tau zoo hauv kev kho mob HIV thiab mob qog noj ntshav.Nyob rau tib lub sij hawm, nws yog siv rau antitussive thiab expectorant, kev kho mob ntawm allergic rhinitis, insomnia, kev nyuaj siab, thiab lwm yam.
Kev lag luam zaub mov:
Muaj cov kev tshawb fawb siv nws ua ib qho kev khaws cia hauv cov khoom noj nqaij.
Kev lag luam tshuaj pleev ib ce:
Cov nyhuv inhibitory ntawm Betulin ntawm collagenase kev ua haujlwm thiab kev loj hlob ntawm cov hlwb ntawm daim tawv nqaij qhia tau hais tias nws muaj zog tiv thaiv kev laus thiab tuaj yeem siv los kho cov tawv nqaij, du ntawm daim tawv nqaij, thiab tiv thaiv cov tawv nqaij tawv.Nws kuj yog ib qho kev pabcuam zoo rau sab nraud.
Tam sim no Betulin tau txais los ntawm kev rho tawm ncaj qha, thiab feem ntau yog los ntawm cov kuab tshuaj reflux extraction thiab recrystallization purification Tshwj xeeb: 1. Extract betulin los ntawm ethanol tov.Tom qab cua sov reflux txog 5h, cov extract yog nqus distilled thiab recrystallized nrog ethanol rau 2 mus rau 3 zaug nrog ethanol kom tau cov khoom crude ntawm betulin.2. Cov khoom crude tau recrystallized los ntawm methanol / chloroform (1: 1) (txhua 80g crude khoom yuav tsum tau 300mL methanol / chloroform tov). Cov sib tov yog tso cai rau sawv ntsug hmo ntuj thiab ces nqus lim kom tau txais dawb koob zoo li betulin.3. Ultrasonic kev kho mob rau 20min thaum refluxing yog nqa tawm, thiab cov extraction yield thiab cov khoom purity ntawm betulin tuaj yeem txhim kho los ntawm kev puas tsuaj ntawm bark lub koom haum.4. Qhov zoo tshaj plaws ntawm supercritical CO2 kua extraction yog raws li nram no: tus nqi ntawm modifier yog 115mL/(g birch bark hmoov);Kev rho tawm siab yog 20MPa;extraction kub yog 55 ℃;kua CO2 ntws tus nqi yog 10kg / h.
