Bicalutamide CAS 90357-06-5 API Hoobkas High Quality Advanced Prostate Cancer

Lus piav qhia luv luv:

Lub npe: Bicalutamide

CAS: 90357-06-5 Nr

Cov tsos mob: Dawb rau Off-White Crystalline Hmoov

Kev Ntsuas: 98.0% ~ 102.0%

Bicalutamide hauv kev kho mob Advanced Prostate Cancer

API High Quality, Commercial Production

Inquiry: alvin@ruifuchem.com

Xa email rau peb

Product Detail

Yam khoom

Khoom cim npe

Nqe lus piav qhia:

Chaw tsim tshuaj paus Supply nrog High Purity thiab ruaj khov zoo
Lub npe: Bicalutamide
CAS: 90357-06-5 Nr
Bicalutamide hauv kev kho mob Advanced Prostate Cancer
API High Quality, Commercial Production

Chemical Properties:

Lub npe	Bicalutamide
Synonyms	N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropionamide
CAS Nr	90357-06-5
CAT Number	RF-API 76
Tshuag xwm txheej	Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms
Molecular Formula	C18H14F4N2O4S
Molecular Luj	430.37 Nws
Cia Kub	2-8 ℃
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Dawb rau Off-White Crystalline Hmoov
Kev Taw Qhia A	IR: Spectrum ntawm tus qauv sib raug raws li tus qauv siv
Kev Qhia B	HPLC: Lub sijhawm khaws cia ntawm lub ncov loj ntawm cov qauv kev daws teeb meem sib raug rau cov qauv kev daws teeb meem
Kev txheeb xyuas C	Organic Fluoride Identification
Solubility	Dawb Soluble hauv Acetone thiab Tetrahydrofuran, Me ntsis Soluble hauv Ethyl Acetate
Melting Point	191.0 ~ 195.0 ℃
Cov ntsiab lus dej (los ntawm KF)	≤ 0.20%
Cov ntsiab lus fluoride	15.9% ~ 18.5%
Poob rau ziab	≤0.50%
Residue ntawm Ignition	≤0.10%
Hnyav Hlau	≤10ppm
Residual Solvents
Tetrahydrofuran	≤ 0.072%
Toluene	≤ 0.089%
N-Hexane	≤ 0.029%
Acetone	≤0.50%
Ethyl Acetate	≤0.50%
Yam khoom muaj feem
N, N'-Dimethyl Acetamide	≤ 0.109%
Bicalutamide Aminobenzonitrile	≤0.10%
Bicalutamide Related Compound A Isomer A	≤0.10%
Bicalutamide Related Compound A Isomer B	≤0.10%
Desfluoro Bicalutamide	≤ 0.20%
2-Fluoro Bicalutamide	≤ 0.20%
Deoxy Bicalutamide	≤ 0.20%
Bicalutamide sulfide	≤0.10%
Tej yam tsis meej tsis meej	≤0.10%
Tag nrho cov impurities	≤0.50%
Particle Loj	90% <10um;50% <5um
Assay	98.0% ~ 102.0% (ntawm lub hauv paus qhuav)
Kev ntsuam xyuas microbiological
Total Viable Aerobic Count	≤500CFU / g
Yeasts thiab Pwm	≤50CFU/g
Txee lub neej	24 Lub Hlis
Test Standard	Enterprise Standard;USP Txuj
Kev siv	API, hauv kev kho mob Advanced Prostate Cancer

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.

Qhov zoo:

FAQ:

Daim ntawv thov:

Bicalutamide (CAS: 90357-06-5) yog ib qho uas tsis yog-steroidal androgen antagonist, uas sib tw androgen receptor nrog androgen, thaiv cellular uptake ntawm androgen, thiab inhibits kev khi ntawm androgens rau lub hom phiaj lub cev.Nws khi nrog androgen receptor uas tsim receptor complex, uas nkag mus rau hauv lub nucleus thiab ua ke nrog cov nucleoprotein, yog li inhibiting qog cell loj hlob.Nws tuaj yeem yog thawj kab tshuaj rau kev kho mob palliative ntawm kev mob qog noj ntshav prostate.Bicalutamide tau tsim tawm hauv tebchaws United Kingdom, nws thawj lub khw thoob ntiaj teb, rau kev kho mob qog noj ntshav prostate ua ke nrog LHRH analog lossis phais castration.Ib qho non-steroidal, peripherally xaiv antiandrogen, bicalutamide inhibits qhov kev txiav txim ntawm dihydrotestosterone thiab testosterone ntawm lub hom phiaj los ntawm kev sib tw khi rau cytosolic androgen receptor.Nws tau raug tshaj tawm tias tau txais txiaj ntsig zoo uas tsis muaj qhov cuam tshuam loj ntawm lub plawv thiab cov kab mob metabolic vim qhov txiaj ntsig ntawm kev tsis muaj kev ua haujlwm steroid.Kev ua tau zoo ntawm bicalutamide raws li kev kho mob monotherapy tau pom hauv kev kho mob.Kev cog lus cov lus teb kuj tau tshaj tawm hauv kev kho mob plab hnyuv, lub mis, pancreas thiab cov qog nqaij hlav ntsws tsis me.