Biotin CAS 58-85-5 Assay 97.5 ~ 100.5% Hoobkas
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom ntawm Biotin (Vitamin H) (CAS: 58-85-5) nrog cov khoom zoo.Ruifu Chemical tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, kev pabcuam zoo heev, me me thiab ntau ntau muaj.Yuav Biotin (CAS: 58-85-5),Please contact: alvin@ruifuchem.com
| Tshuaj npe | Biotin |
| Synonyms | D-Biotin;D(+)-Biotin;Vitamin H;Bios II;Vitamin B7;Coenzyme R;Biotinum |
| Tshuag xwm txheej | Hauv Tshuag, Kev Lag Luam Ntau Lawm |
| CAS Nr | 58-85-5 : kuv |
| Molecular Formula | C10H16N2O3S |
| Molecular Luj | 244.31 g / mol |
| Melting Point | 231.0 ~ 233.0 ℃ (lit.) |
| Dej Solubility | Me ntsis Soluble hauv dej |
| Solubility hauv 0.1mol / L NaOH | Yuav luag Transparency |
| Solubility | Me ntsis Soluble hauv Cawv, Chloroform, Ether |
| COA & MSDS | Muaj |
| Keeb kwm | Shanghai, Suav |
| Hom | Ruifu Tshuaj |
| Cov khoom | Specifications | Cov txiaj ntsig |
| Qhov tshwm sim | Dawb los yog Yuav luag Dawb Dawb Crystalline Hmoov | Dawb Crystalline hmoov |
| Kev txheeb xyuas | IR Match nrog Reference IR Spectrum | Ua raws |
| Lub sijhawm khaws cia | Yuav tsum zoo ib yam li RS | Ua raws |
| Kev sib hloov tshwj xeeb [a]20/D | +89.0° to +93.0° (C = 2 in 0.1 M NaOH) | +90.8 ° |
| Assay | 97.5 ~ 100.5% | 99.8% |
| Poob rau ziab | <0.50% | 0.05% |
| Yam khoom muaj feem | ||
| Tus kheej impurity | <1.00% | Ua raws |
| Tag nrho cov impurities | <2.00% | Ua raws |
| Residual Solvents | ||
| Benzene | <2 ppm | <0.2ppm |
| Toluene | <100ppm | <10ppm |
| DMSO | <5000ppm | <500ppm |
| Microbial Test | ||
| Total Viable Aerobic Count | ≤1000cfu / g | Ua raws |
| Tag nrho cov poov xab thiab pwm suav | ≤100cfu / g | Ua raws |
| Escherichia Coli | NP/ 1 g | / |
| Staphylococcus Aureus | NP/ 1 g | / |
| Pseudomonas Aeruginosa | NP/ 1 g | / |
| Enterobacteria | NP/ 1 g | / |
| Cov kab mob Salmonella | NP/10 g | / |
| Xaus | Cov khoom tau raug kuaj thiab ua raws li cov lus qhia tshwj xeeb | |
Pob:Fluorinated Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, lossis raws li cov neeg siv khoom xav tau.
Cia txias:Khaws lub thawv kaw kom nruj thiab khaws cia rau hauv qhov chaw txias, qhuav (2 ~ 8 ℃) thiab lub tsev tso cua txias kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Shipping:Xa mus thoob ntiaj teb los ntawm huab cua, los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.
DEFINITION Analysis Biotin muaj NLT 97.5% thiab NMT 100.5% ntawm Biotin (C10H16N2O3S).
IDENTIFICATION
• A. INFRARED ABSORPTION <197K>
B. Nws ua tau raws li qhov yuav tsum tau muaj hauv Cov Kev Ntsuas Tshwj Xeeb rau Optical Rotation, Specific Rotation <781S>.
C. Lub sijhawm khaws cia ntawm lub ncov loj ntawm cov qauv kev daws teeb meem sib raug rau qhov kev daws teeb meem Standard, raws li tau txais hauv Assay.
QHIA
• KEV PAB CUAM
Cov tshuaj tsis haum: Dissolve 1 g ntawm sodium perchlorate monohydrate hauv 500 mL dej, ntxiv 1 mL ntawm phosphoric acid, thiab dilute nrog dej mus rau 1000 mL.
Mobile theem: Acetonitrile thiab Buffer tov (8.5: 91.5)
Diluent: Acetonitrile thiab dej (1:4)
Kev daws teeb meem: 0.1 mg / mL ntawm USP Biotin RS hauv Diluent.Sonicate yog tias tsim nyog rau yaj
Cov qauv tshuaj: 0.1 mg / mL ntawm Biotin hauv Diluent.Sonicate yog tias tsim nyog rau yaj.
Chromatographic system
(Saib Chromatography <621>, System Suitability.)
Qauv: LC
Detector: UV 200 nm
Kem: 4.6-mm × 15-cm;3-µm ntim L7
Tus nqi ntws: 1.2 mL / min
Kev txhaj tshuaj loj: 50 µL
Qhov system haum
Qauv: Standard tov
Suitability xav tau
Tus Qauv Zauv: NMT 1.5
Tus txheeb ze tus qauv sib txawv: NMT 2.0% rau kev txhaj tshuaj rov ua dua
Kev tsom xam
Qauv: Cov qauv kev daws teeb meem thiab cov qauv kev daws teeb meem
Xam qhov feem pua ntawm Biotin (C10H16N2O3S) hauv feem ntawm Biotin noj:
Result = (rU/rS) × (CS/CU) × 100
rU = ncov teb los ntawm Sample tov
rS = ncov teb los ntawm Standard tov
CS = concentration ntawm USP Biotin RS nyob rau hauv Standard tov (mg / mL)
CU = concentration ntawm Biotin nyob rau hauv cov qauv tov (mg / mL)
Kev lees paub: 97.5% -100.5%
IMPURITIES
• Muaj feem cuam tshuam
Tsis siv neeg tov, Txawb theem, Diluent, Standard tov, Sample tov, Chromatographic system thiab System haum: Ua raws li qhia hauv Assay.
Kev tsom xam
Qauv: qauv tov
Ntsuas cov lus teb siab kawg ntawm cov qauv kev daws teeb meem.
Xam qhov feem pua ntawm txhua qhov impurity hauv feem ntawm Biotin noj:
Cov txiaj ntsig = (rU/rT) × 100
rU = ncov teb ntawm txhua impurity los ntawm cov qauv tov
rT = sum ntawm lub ncov teb ntawm tag nrho cov peaks los ntawm cov qauv tov
Kev lees txais
Tus kheej impurity: NMT 1.0%
Tag nrho impurities: NMT 2.0%
TSEEM CEEB
• OPTICAL ROTATION, Kev sib hloov tshwj xeeb <781S>
Cov qauv tshuaj: 20 mg / mL hauv 0.1 N sodium hydroxide
Kev lees txais cov qauv: +89 ° txog +93 °
TSEEM CEEB
• PACKAGING THIAB STORAGE: Khaws rau hauv cov thawv kom nruj.
• USP REFERENCE STANDARDS <11>
USP Biotin RS
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
Hazard Symbols Xn - Ua phem
Risk Codes R20/21/22 - Ua phem los ntawm kev nqus pa, tiv thaiv daim tawv nqaij thiab yog tias nqos.
R36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij.
Kev Nyab Xeeb Kev Nyab Xeeb S24/25 - Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag.
S36 - Hnav khaub ncaws tiv thaiv zoo.
S26 - Nyob rau hauv rooj plaub ntawm qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
WGK Germany 1
RTECS XJ9088200
FLUKA BRAND F CODE 8
TSCA Yes
HS Code 2936290000
Toxicity LD50 qhov ncauj hauv Luav:> 2000 mg / kg
Biotin (Vitamin H; Vitamin B7) (CAS: 58-85-5)
Biotin yog dej-soluble vitamin nyob rau hauv yim hom, biotin.Nws yog ib tug coenzyme - los yog pab enzyme - siv nyob rau hauv ntau yam metabolic tshua nyob rau hauv lub cev.Dchemicalbook-biotin koom nrog hauv lipid thiab protein metabolism, pab hloov cov zaub mov rau hauv qabzib, uas lub cev siv tau los ua lub zog.Nws tseem yog ib qho tseem ceeb rau kev tswj cov tawv nqaij, plaub hau thiab mucous daim nyias nyias.
Raws li pub additive, Biotin feem ntau yog siv rau nqaij qaib thiab sow pub.Feem ntau cov feem ntau premixed yog 1% -2%.
Biotin yog khoom noj khoom haus ntxiv.Raws li Tuam Tshoj GB2760-90 cov cai, nws tuaj yeem siv los ua kev lag luam zaub mov raws li kev pabcuam ua haujlwm.Nws muaj physiological zog tiv thaiv kab mob ntawm daim tawv nqaij thiab txhawb lipid metabolism thiab lwm yam.
Biotin yog carboxylase coenzyme, koom nrog ntau cov tshuaj tiv thaiv carboxylation, thiab yog ib qho tseem ceeb coenzyme hauv metabolism hauv qab zib, protein thiab rog.
Biotin yog siv los ua zaub mov fortifier.Biotin yog siv rau cov khoom noj me nyuam mos uas muaj 0.1 ~ 0.4mg / kg, hauv cov kua haus 0.02 ~ 0.08mg / kg.
Biotin tuaj yeem siv los sau cov proteins, antigens, tshuaj tiv thaiv kab mob, nucleic acids (DNA, RNA) thiab lwm yam.
Biotin tuaj yeem ua rau cov plaub hau elastic, tiv thaiv cov plaub hau thaum ntxov thiab txhim kho lub ntuj tiv thaiv ntawm daim tawv nqaij.Nws kuj muaj qee yam kev ua haujlwm ntawm kev tiv thaiv wrinkle.Nws tuaj yeem txhim kho tag nrho cov txheej txheem ntawm daim tawv nqaij, ua kom cov ntsia hlau hloov tau yooj yim, txhim kho cov qauv ntawm cov ntsia hlau nkig thiab ua rau cov rau tes zoo dua thiab du los ntawm kev txhawb nqa cov synthesis ntawm lipids.
Qhov tsis muaj biotin tuaj yeem ua rau dermatitis, atrophic glossitis, hyperesthesia, myalgia, malaise, anorexia, thiab mob me me, thiab cov tsos mob ploj nrog biotin supplementation.Nws cov kev mob tshwm sim feem ntau yog qhov tshwm sim ntawm cystic pob txuv.Tab sis rau cov neeg feem coob, txawm tias kev noj ntau dhau ntawm cov vitamin no tsis ua rau muaj qhov tsis zoo.Txawm li cas los xij, cov poj niam cev xeeb tub yuav tsum tsis txhob noj biotin vim muaj kev pheej hmoo ntawm nchuav menyuam.
Cov tshuaj toxicity ntawm Biotin zoo li tsis tshua muaj, kev kho mob ntawm seborrheic dermatitis nrog cov koob tshuaj ntau ntawm Biotin tsis qhia cov metabolism hauv cov protein ntau lossis cov caj ces tsis raug thiab lwm yam metabolic abnormality.Tsiaj thwmsim kuj pom me ntsis toxicity ntawm Biotin.
