Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8 Purity ≥99.5% (HPLC) Sitagliptin Phosphate Monohydrate Intermediate
Muab Sitagliptin Phosphate Monohydrate Related Intermediates:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
Tom ntej: 2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3
Tshuaj npe | Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid |
Synonyms | (R)-Sitagliptin N-Boc-Acid Impurity |
CAS Nr | 486460-00-8 |
CAT Number | Qauv: RF-PI1192 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C15H18F3NO4 |
Molecular Luj | 333.31 Nws |
Melting Point | 136.0 ~ 138.0 ℃ |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Off-White Powder |
Kev txheeb xyuas los ntawm HPLC | Lub Sijhawm khaws cia ntawm Cov Qauv yog Concordant Nrog Reference Standard |
Poob rau ziab | ≤0.50% |
Sulfated tshauv | ≤0.50% |
Hnyav Hlau | <20 ppm |
Isomer | ≤0.50% |
Yam khoom muaj feem | |
impurity A | ≤0.50% |
Lwm Yam Ib Leeg Impurity | ≤0.50% |
Tag nrho cov impurities | ≤0.50% |
Purity | ≥99.5% (HPLC) |
Test Standard | Enterprise Standard |
Kev siv | Intermediate ntawm Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo.
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Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid (CAS: 486460-00-8) yog ib qho tseem ceeb nruab nrab rau kev npaj ntawm sitagliptin.Sitagliptinphosphate yog thawj dipeptidase -IV (DPP-4) inhibitor pom zoo los ntawm FDA hauv 2006. Nws yog siv rau kev kho mob ntawm hom II mob ntshav qab zib mellitus.Nws muaj cov nyhuv hypoglycemic pom tseeb thaum siv ib leeg lossis ua ke nrog metformin thiab pioglitazone, thiab nws muaj kev nyab xeeb rau noj, zoo zam, nrog qee qhov tsis zoo tshwm sim.Thaum Lub Yim Hli 2009, cov tshuaj tau pom zoo los ntawm European Union ua thawj kab tshuaj rau kev kho mob ntshav qab zib hom 2.Tom qab xyoo 2011, ib qho tom qab lwm lub tebchaws tau pom zoo ua ke ntawm sitagliptin phosphate thiab alpha glycosidase inhibitors lossis insulin.Sitagliptin phosphate yog thawj FDA-pom zoo dipeptidyl peptidase-IV inhibitor los siv rau hauv kev kho mob ntshav qab zib hom 2 nyob deb, raws li lub npe lag luam Januvia.
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Sitagliptin CAS 486460-32-6 Purity > 99.0% (HPLC ...
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Sitagliptin Phosphate Monohydrate CAS 654671-77 ...
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2,4,5-Trifluorophenylacetic Acid CAS 209995-38-...
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Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Buty...
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Sitagliptin Triazole Hydrochloride CAS 762240-9 ...
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Sitagliptin Phosphate Monohydrate Intermediate ...