Brexpiprazole CAS 913611-97-9 Purity > 99.0% (HPLC) API Hoobkas
Ruifu Chemical Supply Brexpiprazole Intermediates
Brexpiprazole CAS 913611-97-9
7-Hydroxyquinolinone CAS 70500-72-0
4-Bromobenzo [b]thiophene CAS 5118-13-8
1-(1-benzothiophen-4-yl)piperazine Hydrochloride CAS 913614-18-3
7-(4-Chlorobutoxy)quinolin-2(1H)-ib CAS 913613-82-8
4-Chlorobenzo [b]thiophene CAS 66490-33-3
Tshuaj npe | Brexpiprazole |
Synonyms | OPC-34712;7-(4-(4-(Benzo[b]thiophen-4-yl)piperazin-1-yl)butoxy)quinolin-2(1H)-ib |
CAS Nr | 913611-97-9 |
CAT Number | RF-PI 1982 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C25H27N3O2S |
Molecular Luj | 433.57 ib |
Qhov ntom | 1.245 ± 0.060g / cm3 |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb los yog Off-White Crystalline Hmoov |
Kev txheeb xyuas | Los ntawm IR |
RT | Nyob rau hauv chirality yuav tsum ua raws |
Chloride | Nws muab cov tshuaj tiv thaiv chloride |
Dej | 3.0% ~ 4.5% |
Melting Point | 198.0 ~ 202.0 ℃ |
Residue ntawm Ignition | <0.20% |
Hnyav Hlau | ≤10ppm |
Yam khoom muaj feem | |
Tus kheej impurity | <0.50% |
Tag nrho cov impurities | <1.00% |
EE | > 99.0% |
Purity / Analysis Method | > 99.0% (HPLC, raws li qhuav) |
Test Standard | Enterprise Standard |
Kev siv | API |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
Brexpiprazole (CAS: 913611-97-9) yog ib qho tshuaj siv tau zoo hauv kev kho thiab tiv thaiv kev puas hlwb nrog rau CNS mob.Brexpiprazole yog ib qho tshuaj tiv thaiv kev puas siab puas ntsws tshiab uas ua haujlwm ua serotonin ® dopamine kev ua haujlwm modulator thiab tau pom tias muaj txiaj ntsig zoo li kev kho mob ntxiv rau cov neeg mob uas muaj kev nyuaj siab loj (MDD).Brexpiprazole nthuav tawm cov tshuaj tshwj xeeb tshwj xeeb, ua haujlwm ib feem ntawm serotonin 5-HT1A thiab dopamine D2 receptors thiab ua tus antagonist tag nrho ntawm 5-HT2A thiab noradrenaline α1B / 2C receptors, nrog zoo sib xws subnanomolar binding affinity.Brexpiprazole yog tsim los ntawm Otsuka thiab Lundbeck, tau pom zoo nyob rau hauv 2015 los ntawm FDA rau kev kho mob ntawm tus mob schizophrenia thiab raws li ib tug adjunctive kev kho mob rau kev nyuaj siab.Brexpiprazole yog dav suav hais tias yog ib tug successor rau Otsuka cov tshuaj antipsychotic aripiprazole (lub npe lag luam Abilify) uas nws patent tas rau lub yim hli ntuj 2014.