Brigatinib CAS 1197953-54-0 Purity > 99.0% (HPLC)

Lus piav qhia luv luv:

Lub npe tshuaj: Brigatinib

Cov ntsiab lus: AP-26113

CAS: 1197953-54-0 Nr

Purity:> 99.0% (HPLC)

Cov tsos mob: Dawb rau Off-White hmoov

Hu rau: Dr. Alvin Huang

Txawb/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Product Detail

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1197953-54-0 -Nqe lus piav qhia:

Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom ntawm Brigatinib (AP-26113) (CAS: 1197953-54-0) nrog cov khoom zoo.Ruifu Chemical tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, kev pabcuam zoo heev, me me thiab ntau ntau muaj.Yuav Brigatinib,Please contact: alvin@ruifuchem.com

1197953-54-0 -Chemical Properties:

Tshuaj npe	Brigatinib
Synonyms	AP26113;AP-26113;5-Chloro-N4-[2-(Dimethylphosphinyl)phenyl]-N2-[2-Methoxy-4-[4-(4-Methyl-1-Piperazinyl)-1-Piperidinyl]phenyl]-2,4-Pyrimidinediamine
Tshuag xwm txheej	Hauv Tshuag, Kev Lag Luam Ntau Lawm
CAS Nr	1197953-54-0
Molecular Formula	C29H39ClN7O2P
Molecular Luj	584,09 g / mol
Melting Point	≥203 ℃ (txog.)
Qhov ntom	1.31 ± 0.10g / cm3
COA & MSDS	Muaj
Keeb kwm	Shanghai, Suav
Hom	Ruifu Tshuaj

1197953-54-0 -Specifications:

Cov khoom	Specifications	Cov txiaj ntsig
Qhov tshwm sim	Dawb rau Off-White Powder	Ua raws
Purity / Analysis Method	> 99.0% (HPLC)	99.26%
Max.Ib leeg Impurity	<1.00%	0.25%
Poob rau ziab	<1.00%	0.27%
Infrared Spectrum	Raws li tus qauv	Ua raws
1 H NMR Spectrum	Raws li tus qauv	Ua raws
Xaus	Cov khoom tau raug kuaj thiab ua raws li cov lus qhia tshwj xeeb

Pob / Cia /Kev xa khoom:

Pob:Fluorinated Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, lossis raws li cov neeg siv khoom xav tau.
Cia txias:Khaws lub thawv kaw kom nruj thiab khaws cia rau hauv qhov chaw txias, qhuav thiab zoo-ventilated warehouse kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Shipping:Xa mus thoob ntiaj teb los ntawm huab cua, los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.

Qhov zoo:

Muaj peev xwm txaus: Muaj cov chaw txaus thiab cov kws tshaj lij

Kev Pabcuam Kev Ua Haujlwm: Ib qho kev pabcuam kev yuav khoom

Pob OEM: Kev cai pob thiab daim ntawv lo muaj

Kev xa khoom sai: Yog tias nyob hauv Tshuag, peb hnub xa khoom lav

Stable Supply: Khaws cov khoom tsim nyog

Kev them nyiaj yug Technical: Technology tov muaj

Kev Pabcuam Synthesis: Ntau yam ntawm grams mus rau kilos

High Quality: Tsim kom muaj kev ruaj ntseg zoo

FAQ:

Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.

Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.

Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.

ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.

Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.

Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.

MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.

Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.

Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.

Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.

Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.

Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.

1197953-54-0 - Cov lus piav qhia dav dav:

Brigatinib (AP-26113) (CAS: 1197953-54-0) yog ib qho kev tshawb nrhiav me me-molecule tsom rau kev kho mob qog noj ntshav tau tsim los ntawm ARIAD Pharmaceuticals, Inc. Brigatinib yog cov tshuaj siv los kho mob qog noj ntshav uas suppresses epidermal growth factor receptor (EGFR) thiab anaplastic lymphoma kinase (ALK).Brigatinib yog ib qho kev xaiv agonist tiv thaiv kev hloov pauv ntawm EGFR as opposed to the wild mutant forms.Cov tshuaj kuj piav qhia txog kev xaiv tawm tsam ALK-EML4 fusion gene, uas yog ib qho tseem ceeb ntawm kev hloov kho ntawm lub ntsws parenchyma.Brigatinib yog tshuaj rau cov neeg mob uas muaj cov caj ces txawv txav thiab thaum cov qog nqaij hlav tsis me me (NSCLC) tsis teb rau kev tswj hwm nrog lwm cov tshuaj.Brigatinib yog cais raws li kinase inhibitor, uas nws cov txheej txheem ntawm kev ua haujlwm cuam tshuam rau kev ua haujlwm ntawm cov proteins uas txawv txav uas txhim kho kev sib npaug ntawm cov qog nqaij hlav cancer.

1197953-54-0 - Cov lus qhia:

Brigatinib (CAS: 1197953-54-0) yog tshuaj rau cov neeg mob uas muaj cov ntaub ntawv tshwj xeeb ntawm NSCLC uas tau kis mus rau ntau ntu ntawm lub cev hauv cov neeg uas tau kho yav dhau los nrog lwm cov tshuaj mob qog noj ntshav xws li Crizotinib, thiab lawv tus mob tau mob hnyav dua. los yog lawv qhia me ntsis txog kev txhim kho.Nws feem ntau yog nyob rau hauv kev tshawb nrhiav rau nws txoj kev kho mob ntawm cov qog nqaij hlav tsis me me (NSCLC) qhov twg ALK tau qhib thiab EGFP kev hloov pauv nquag tshwm sim.

1197953-54-0 - Daim ntawv thov:

Brigatinib (AP-26113) (CAS: 1197953-54-0) yog ib tiam tshiab inhibitor ntawm tyrosine kinase, uas qhia tau hais tias muaj txiaj ntsig zoo hauv ALK + metastatic NSCLC.Thaum Lub Yim Hli 30, 2016, Tebchaws Asmeskas FDA tau tso cai bugtinib raws li kev kho mob thiab tsis tshua muaj tshuaj rau ALK + NSCLC hauv cov neeg mob uas tau tsim lossis tsis tuaj yeem ua rau Crizotinib, thawj tiam ALK + NSCLC kev kho mob.Muab qhov tseem ceeb rau kev txheeb xyuas daim ntawv teev npe thiab tso cai rau cov ntaub ntawv thov xa tuaj rau ntawm lub hauv paus dov.FDA pom zoo Bugtinib rau lub Plaub Hlis 28, 2017, raws li lub npe lag luam Alunbrigtm.