Brimonidine Tartrate CAS 70359-46-5 Kev Ntsuam Xyuas 99.0% ~ 101.0%
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom ntawm Brimonidine Tartrate (CAS: 70359-46-5) nrog cov khoom zoo.Selective α2-adrenergic receptor agonist, ib qho tshuaj siv los kho qhov qhib-angle glaucoma lossis ocular hypertension.Ruifu Chemical tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, kev pabcuam zoo heev, me me thiab ntau ntau muaj.Yuav Brimonidine Tartrate,Please contact: alvin@ruifuchem.com
| Tshuaj npe | Brimonidine Tartrate |
| Synonyms | Brimonidine L-Tartrate;UK 14304 Tartrate;AGN190342 Tartrate;5-Bromo-N-(4,5-Dihydro-1H-Imidazol-2-yl)quinoxalin-6-Amine Tartrate;5-Bromo-N-(4,5-Dihydro-1H-Imidazol-2-yl)-6-Quinoxalinamine Tartrate;5-Bromo-N-(4,5-Dihydro-1H-Imidazol-2-yl)quinoxalin-6-Amine (2R,3R)-2,3-Dihydroxysuccinate |
| Tshuag xwm txheej | Hauv Tshuag, Kev Lag Luam Ntau Lawm |
| CAS Nr | 70359-46-5 |
| Molecular Formula | C11H10BrN5 · C4H6O6 |
| Molecular Luj | 442.23 g / mol |
| Melting Point | 207.0 ~ 208.0 ℃ (Lub Kaum Ob Hlis) |
| rhiab heev | Cua Sensitive, Thaum tshav kub kub Sensitive |
| COA & MSDS | Muaj |
| Keeb kwm | Shanghai, Suav |
| Txee lub neej | 24 Lub Hlis yog khaws cia kom raug |
| Qeb | API (Active Pharmaceutical Ingredient) |
| Hom | Ruifu Tshuaj |
| Cov khoom | Specifications | Cov txiaj ntsig |
| Qhov tshwm sim | Dawb los yog daj me ntsis los yog Me ntsis Brownish hmoov | Ua raws |
| Kev Taw Qhia A | Specific Optical Rotation | Ua raws |
| Kev Qhia B | Infrared Absorption Spectrophotometer | Ua raws |
| Solubility | Soluble nyob rau hauv dej, xyaum insoluble nyob rau hauv anhydrous ethanol thiab nyob rau hauv toluene | Ua raws |
| Specific Optical Rotation | +9.0° ~ +10.5° | + 9.6 ° C |
| Poob rau ziab | ≤0.50% | 0.20% |
| Sulfated tshauv | ≤ 0.20% | 0.07% |
| Hnyav Hlau | ≤ 20ppm | <20 ppm |
| Yam khoom muaj feem | ||
| Specified impurities | ||
| N-(imidazolidin2yliden) quinoxalin-6-amine | ≤0.10% | Ua raws |
| 5-bromoqulinoxalin-6-amine | ≤0.10% | Ua raws |
| Quinoxalin-6-amine | ≤0.10% | Ua raws |
| 1-(5-bromoquinoxalin-6-yl)thiourea | ≤0.10% | Ua raws |
| 2-(5-bromoquinoxalin-6-yl)guanidine | ≤0.10% | Ua raws |
| 5-bromo-N-(1H-imidazol-2-yl) Quinoxalin-6-amine | ≤0.10% | Ua raws |
| 1-(2-aminoethyl)-3-(5-bromoquinoxalin-6-yl) urea | ≤0.10% | Ua raws |
| Unspecified impurities | ≤0.10% | Ua raws |
| Tag nrho | ≤ 0.20% | 0.12% |
| Assay | 99.0% ~ 101.0% (nyob rau hauv qhuav qhuav) | 99.8% |
| Xaus | Cov khoom no los ntawm kev soj ntsuam raws li BP2015 Standard | |
Pob:Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws lub thawv kaw kom nruj thiab khaws cia rau hauv qhov chaw txias, qhuav (2 ~ 8 ℃) thiab lub tsev tso cua txias kom deb ntawm cov khoom tsis sib xws.Tsis txhob raug tshav ntuj ncaj qha, noo noo thiab kub heev.
Shipping:Xa mus thoob ntiaj teb los ntawm huab cua, los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
Hazard Statements H301: Toxic yog nqos.
Cov Lus Qhia Ua Ntej
P501: Pov tseg cov ntsiab lus / ntim rau hauv qhov chaw pov tseg pov tseg uas pom zoo.
P270: Tsis txhob noj, haus lossis haus luam yeeb thaum siv cov khoom no.
P264: Ntxuav daim tawv nqaij kom huv si tom qab tuav.
P301 + P310 + P330: YOG SWALLOWED: Tam sim ntawd hu rau lub chaw POISON CENTER/tus kws kho mob.Yaug qhov ncauj.
P405: Lub khw kaw.
Txoj Cai Hais Txog:
Cov ntaub ntawv thauj mus los:
UN Number (DOT-AIR) UN2811
Chav Kawm (DOT-AIR) 6.1
Packing Group (TCI-A) III
HS 2933.29.9000
Brimonidine Tartrate (CAS: 70359-46-5) yog ib qho kev xaiv α2-receptor blocker, ua tiav los ntawm US Company Allergan, uas yog tshuaj kho qhov muag.Nws tuaj yeem txo qhov siab intraocular siab (IOP).Brimonidine Tartrate ophthalmic solution saling nyob rau hauv kev ua lag luam yog Brimonidine Tartrate daim ntawv, uas yog ib tug zoo IOP-txo cov tshuaj rau mob qhib-angle glaucoma thiab ocular hypertension kev kho mob ntawm cov neeg mob, tab sis kuj rau argon laser IOP qib.Brimonidine Tartrate ophthalmic tov muaj ib tug dual mechanism ntawm kev txiav txim los ntawm kev txo cov aqueous lom zem ntau lawm thiab ua rau cov xim txheej ntawm cov kua scleral outflow kho lub hom phiaj.Tom qab tso rau hauv lub qhov muag, cov nyhuv yog nrawm, thiab nws tuaj yeem ncav cuag lub ncov thaum siv txog li 2h, thiab lub sijhawm zoo tuaj yeem tswj tau 12h.Ntshav tsuas tuaj yeem kuaj pom cov tshuaj.Cov khoom no muaj cov metabolism hauv thawj zaug hauv lub siab, thiab cov metabolites tawm hauv cov zis los ntawm ob lub raum.Kev nqus thiab kev faib tawm tsis raug cuam tshuam, thiab cov neeg laus tsis tas yuav hloov cov koob tshuaj.Brimonidine Tartrate ophthalmic tov piv nrog rau lwm cov α-blockers, cov rog-soluble yog me me, thaum nws tsis yooj yim mus hla cov ntshav-hlwb barrier thiab tsis tsim sedation, hypotension thiab lwm yam zoo xws li clonidine central adverse reactions.Brimonidine Tartrate Ophthalmic Solution yog qhov kev xaiv zoo rau α2-adrenergic receptors, thiab α2 / α1 piv ntawm receptor affinity yog ntau tshaj 1000 zaug.Cov nyhuv ntawm alpha 2 receptors tuaj yeem ua rau txo qis hauv lub cev.Thiab lub luag haujlwm ntawm alpha 1 receptors tuaj yeem ua rau vascular contraction, daim tawv muag retraction lossis txo qis thiab nthuav dav ntawm cov menyuam kawm ntawv.Daim ntawv thov ntev ntawm cov khoom no yuav tsis ua rau desensitization sai.Tsis tas li ntawd, piv nrog β-blockers, Brimonidine Tartrate qhov muag tee rau cov teebmeem me me, nws tsis cuam tshuam rau lub ntsws ua haujlwm, yog li nws tsim nyog rau cov neeg mob xiam oob qhab β-blockers.Tsis tas li ntawd, thaum siv ib leeg β-blocker, nws tsis tuaj yeem ua tiav cov hom phiaj kho mob, thiab koj tuaj yeem nce qib FDA ib txhij.
