Candesartan CAS 139481-59-7 Purity > 99.0% (HPLC) Hoobkas
Ruifu Chemical Supply Candesartan Cilexetil Intermediate Nrog Siab Purity
Candesartan Cilexethyl CAS 145040-37-5
Candesartan CAS 139481-59-7
1-Chloroethyl Cyclohexyl Carbonate CAS 99464-83-2
Candesartan Cilexetil Intermediate Eethyl Ester C6 CAS 139481-41-7
Candesartan Cilexetil Intermediate CAS 139481-44-0
Trityl Candesartan Cileexetil CAS 170791-09-0
Tshuaj npe | Candesartan |
Synonyms | CV-11974;2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-Benzimidazole-7-Carboxylic Acid;3-[[2'-(1H-Tetrazol-5-yl)biphenyl-4-yl]methyl]-2-ethoxy-3H-Benzimidazole-4-Carboxylic Acid;Candesartan M1;Candesartan Cilexetil EP Impurity G |
CAS Nr | 139481-59-7 |
CAT Number | Qauv: RF-PI1889 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C24H20N6O3 |
Molecular Luj | 440.45 Nws |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb hmoov |
Identification-HPLC | Lub Sijhawm Retention Similar to Standard |
ID-IR | Zoo ib yam li Standard |
Purity / Analysis Method | > 99.0% (HPLC) |
Melting Point | 183.0 ~ 185.0 ℃ |
Poob rau ziab | <0.50% |
Moisture (KF) | <0.50% |
Residue ntawm Ignition | <0.50% |
Hnyav Hlau | <20 ppm |
Tus kheej impurity | <1.00% (HPLC) |
Tag nrho cov impurities | <1.00% (HPLC) |
Refractive Index | n20/D 1.745~1.747 |
Test Standard | Enterprise Standard |
Kev siv | API;Rau Kev Kho Mob Ntshav Siab |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
Candesartan (CAS: 139481-59-7) yog angiotensin II receptor antagonist nrog IC50 ntawm 0.26 nM.Lub Hom Phiaj: Angiotensin II Receptor candesartan yog qhia rau kev kho mob ntshav siab.Candesartan Cilexetil tau pom zoo thawj zaug hauv GB thaum Lub Plaub Hlis 29, 1997, tom qab ntawv pom zoo los ntawm US Food and Drug Administration (FDA) thaum Lub Rau Hli 4, 1998, thiab tau pom zoo los ntawm Pharmaceuticals thiab Medical Devices Agency of Japan (PMDA) thaum Lub Peb Hlis 12, 1999. Nws tau tsim los ntawm AstraZeneca, tom qab ntawd ua lag luam raws li Atacand los ntawm AstraZeneca hauv GB thiab Asmeskas, thiab ua lag luam raws li Blopress los ntawm Takeda hauv JP.Candesartan Cilexetil yog angiotensin II receptor blocker (ARB), nws thaiv cov vasoconstrictor thiab aldosterone-secreting teebmeem ntawm angiotensin II los ntawm kev xaiv thaiv kev khi ntawm angiotensin II rau AT1 receptor nyob rau hauv ntau cov ntaub so ntswg, xws li vascular du nqaij thiab cov qog adrenal.Atacand tau qhia rau kev kho mob ntshav siab hauv cov neeg laus thiab cov menyuam yaus hnub nyoog 1 txog <17 xyoo, lub plawv tsis ua haujlwm (NYHA chav kawm II-IV) thiab siv los txo cov hlab plawv tuag thiab mob plawv tsis ua haujlwm hauv tsev kho mob.