Capecitabine CAS 154361-50-9 Purity 98.0% ~ 102.0% API Siab Zoo
Commercial Supply Capecitabine Related Intermediates:
5-Fluorocytosine CAS: 2022-85-7
Tom ntej: 2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine CAS: 161599-46-8
Tom ntej: 1,2,3-Tri-O-acetyl-5-deoxy-β-D-ribofuranose CAS: 62211-93-2
Capecitabine CAS NO: 154361-50-9
| Tshuaj npe | Capecitabine |
| CAS Nr | 154361-50-9 |
| CAT Number | RF-API 08 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
| Molecular Formula | C15H22FN3O6 |
| Molecular Luj | 359.35 Nws |
| Melting Point | 110.0 ~ 121.0 ℃ |
| Shipping Condition | Nyob rau hauv Ambient Kub |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Dawb hmoov |
| Kev txheeb xyuas | IR Spectrum qauv yuav tsum sib haum nrog spectrum ntawm tus qauv siv |
| Kev txheeb xyuas | HPLC: Lub sijhawm khaws cia ntawm qhov tseem ceeb ntawm cov qauv kev daws teeb meem yuav tsum ua raws li tus qauv siv. |
| Purity | 98.0% ~ 102.0% (raws li anhydrous thiab hnyav-dawb hauv paus) |
| Kev hloov kho qhov muag | +96.0° ~ + 100° |
| Moisture (KF) | ≤ 0.30% |
| Residue ntawm ignition | ≤0.10% |
| Hnyav Hlau | ≤ 20ppm |
| Related Impurity A | ≤ 0.30% |
| Related Impurity B | ≤ 0.30% |
| Related Impurity C | ≤0.10% (2',3'-Di O-Acety-5'-deoxy-5-Fluoroytidine) |
| Ib leeg tsis hais txog impurity | ≤0.10% |
| Tag nrho Unspecified Impurities | ≤0.50% |
| Tag nrho cov impurities | ≤ 1.5% |
| Residual Solvents (GC) | |
| Methanol | ≤3000ppm |
| Ethanol | ≤5000ppm |
| Dichloromethane | ≤600ppm |
| Ethyl Acetate | ≤5000ppm |
| Toluene | ≤800ppm |
| Pyridine | ≤200ppm |
| Hexane | ≤290ppm |
| Tag nrho Aerobic Microbial suav | ≤200cfc/g |
| Poov xab thiab Moulds suav | ≤50cfc/g |
| Test Standard | Tebchaws Asmeskas Pharmocopoeia (USP) |
| Kev siv | Metastatic mis Cancer |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
Capecitabine (CAS: 154361-50-9) yog ib daim ntawv tshiab ntawm qhov ncauj fluorinated pyrimidine tshuaj.Capecitabine tau tsim los ntawm Roche Pharmaceuticals, thiab nws lub npe lag luam yog Xeloda.Capecitabine tuaj yeem hloov pauv hauv vivo rau hauv 5- FU, ib qho tshuaj tiv thaiv metabolizim fluorine pyrimidine deoxynucleoside carbamate cov tshuaj uas tsom rau cov qog nqaij hlav qog noj ntshav kom inhibit cell faib thiab cuam tshuam RNA thiab protein synthesis.Nws cov teebmeem cuam tshuam rau qib ntawm TP enzyme qhia hauv cov ntaub so ntswg neoplastic thiab rau DPD enzyme hauv vivo qhia.Nws yog qhov tsim nyog rau kev kho mob ntxiv rau cov neeg mob qog nqaij hlav cancer mis metastatic uas tsis tau teb rau paclitaxel lossis anthracycline tshuaj tua kab mob.Raws li cov tshuaj tiv thaiv kab mob, nws feem ntau yog siv los kho tus mob qog noj ntshav siab tshaj plaws lossis mob qog noj ntshav, nrog rau kev kho mob rau cov qog nqaij hlav tsis me hauv lub ntsws, mob qog noj ntshav, mob qog noj ntshav, mob qog noj ntshav, mob qog noj ntshav, mob qog noj ntshav, mob plab, thiab lwm yam qog nqaij hlav. .
