4-Isothiocyanato-2-(Trifluoromethyl)benzonitrile CAS 143782-23-4 Enzalutamide Intermediate Purity > 98.0% (GC)
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom ntawm 4-Isothiocyanato-2-(Trifluoromethyl) benzonitrile (CAS: 143782-23-4) nrog cov khoom zoo, nruab nrab ntawm Enzalutamide (CAS: 915087-33-1).Ruifu Chemical tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, kev pabcuam zoo heev, me me thiab ntau ntau muaj.Yuav Enzalutamide Intermediates,Please contact: alvin@ruifuchem.com
Tshuaj npe | 4-Isothiocyanato-2-(Trifluoromethyl) benzonitrile |
Synonyms | 4-Cyano-3-(Trifluoromethyl) phenyl Isothiocyanate;Isothiocyanic Acid 4-Cyano-3-(Trifluoromethyl) phenyl Ester;4-Isothiocyanato-2-Trifluoromethylbenzonitrile;3-Fluoro-4-Methylphenylisothiocyanate |
Tshuag xwm txheej | Hauv Tshuag, Kev Lag Luam Ntau Lawm |
CAS Nr | 143782-23-4 |
Molecular Formula | C9H3F3N2S |
Molecular Luj | 228.19 g / mol |
Melting Point | 39.0 txog 43.0 ℃ |
Boiling Point | 331 ℃ |
Flash Point | 154 ℃ |
Qhov ntom | 1.31 ib |
rhiab heev | Moisture Sensitive, Thaum tshav kub kub Sensitive |
COA & MSDS | Muaj |
Qauv | Muaj |
Keeb kwm | Shanghai, Suav |
Hom | Ruifu Tshuaj |
Cov khoom | Specifications | Cov txiaj ntsig |
Qhov tshwm sim | Off-White hmoov | Off-White hmoov |
Melting Point | 39.0 txog 43.0 ℃ | 41.2 ℃ |
Poob rau ziab | <0.50% | 0.19% |
Purity / Analysis Method | > 98.0% (HPLC) | 98.8% |
Infrared Spectrum | Raws li tus qauv | Ua raws |
1 H NMR Spectrum | Raws li tus qauv | Ua raws |
Xaus | Cov khoom tau raug kuaj thiab ua raws li cov lus qhia tshwj xeeb | |
Daim ntawv thov | Intermediate ntawm Enzalutamide (CAS: 915087-33-1) |
Pob:Fluorinated Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, lossis raws li cov neeg siv khoom xav tau.
Cia txias:Khaws lub thawv kaw kom nruj thiab khaws cia rau hauv qhov chaw txias, qhuav (2 ~ 8 ℃) thiab lub tsev tso cua txias kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Shipping:Xa mus thoob ntiaj teb los ntawm huab cua, los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
H302 + H312 + H332: Ua phem yog tias nqos tau, sib cuag nrog daim tawv nqaij lossis yog nqus tau.
H315: Ua rau tawv nqaij khaus.
H319: Ua rau mob qhov muag loj.
H335: Tej zaum yuav ua rau ua pa ua pa.
P501: Pov tseg cov ntsiab lus / ntim rau hauv qhov chaw pov tseg pov tseg uas pom zoo.
P261: Tsis txhob ua pa plua plav / fume / gas / pos huab / vapors / tshuaj tsuag.
P270: Tsis txhob noj, haus lossis haus luam yeeb thaum siv cov khoom no.
P271: Siv sab nraum zoov lossis hauv qhov chaw uas muaj cua zoo xwb.
P264: Ntxuav daim tawv nqaij kom huv si tom qab tuav.
P280: Hnav cov hnab looj tes tiv thaiv / tiv thaiv khaub ncaws / tiv thaiv qhov muag / tiv thaiv ntsej muag.
P337 + P313: Yog qhov muag khaus tshwm sim: Tau txais cov lus qhia kho mob / saib xyuas.
P305 + P351 + P338: YOG HAIV NEEG: Yaug ceev faj nrog dej rau ob peb feeb.Tshem cov looj ntsej muag, yog tias tam sim no thiab yooj yim ua.Txuas ntxiv yaug.
P332 + P313: Yog tias khaus tawv nqaij tshwm sim: Tau txais lus qhia kho mob / saib xyuas.
P362: Tshem cov khaub ncaws tsis huv thiab ntxuav ua ntej rov siv dua.
P301 + P312 + P330: YOG SWALLOWED: Hu rau lub chaw POISON / tus kws kho mob yog tias koj tsis xis nyob.Yaug qhov ncauj.
P302 + P352 + P312: YOG HAIV NEEG: Ntxuav nrog dej kom ntau. Hu rau POISON CENTER / tus kws kho mob yog tias koj tsis xis nyob.
P304 + P340 + P312: YOG IN HALED: Tshem tus neeg mus rau huab cua ntshiab thiab ua pa kom xis nyob.Hu rau POISON CENTER/tus kws kho mob yog tias koj tsis xis nyob.
P403 + P233: Khaws rau hauv qhov chaw muaj cua zoo.Khaws lub thawv kaw kom nruj.
P405: Lub khw kaw.
4-Isothiocyanato-2-(Trifluoromethyl)benzonitrile (CAS: 143782-23-4) yog siv los ua ib qho nruab nrab ntawm Enzalutamide (CAS: 915087-33-1).Enzalutamide (XTANDI) yog qhov ncauj androgen receptor antagonist, uas tau pom zoo los ntawm kev tshawb fawb soj ntsuam tam sim no thiab US FDA (Food and Drug Administration), rau kev txhim kho tom qab kws khomob metastatic castration kam rau ua rau mob qog noj ntshav prostate Kev kho mob (xws li cov neeg mob qog noj ntshav prostate. tom qab kws khomob, mob qog noj ntshav lossis qog nqaij hlav cancer tseem loj hlob hauv cov neeg mob zoo li no), tuaj yeem txuas ntxiv txoj sia nyob ntawm cov neeg mob.Thaum Lub Yim Hli 2012, US FDA tau pom zoo enzalutamide rau kev kho mob ntawm metastatic castration-resistant prostate cancer (mCRPC) hauv cov neeg mob uas tau kho yav dhau los.Docetaxel.