CAS 177036-94-1 Purity > 99.0% (HPLC) API Hoobkas High Purity

Lus piav qhia luv luv:

CAS: 177036-94-1 Nr

Purity:> 99.0% (HPLC)

Cov tsos mob: Dawb los yog Off-White hmoov

Kev Kho Mob Pulmonary Arterial Hypertension (PAH)

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Product Detail

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Khoom cim npe

Nqe lus piav qhia:

Kev Lag Luam Kev Lag Luam (CAS: 177036-94-1) Cov Neeg Nruab Nrab cuam tshuam:
CAS: 177036-94-1 Nr
Tom ntej: Methyl 2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoate CAS: 178306-47-3
Tom ntej: 2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoic Acid CAS: 178306-51-9
(S)-2-Hydroxy-3-Methoxy-3,3-Diphenylpropionic Acid CAS: 178306-52-0
L-Proline Methyl Ester Hydrochlorid CAS: 2133-40-6
Tom ntej: 4,6-Dimethyl-2-(Methylsulfonyl)pyrimidine CAS: 35144-22-0

Chemical Properties:

Tshuaj npe	(S)-2-[(4,6-Dimethylpyrimidin-2-yl)oxy]-3-Methoxy-3,3-Diphenylpropionic Acid
Synonyms	(+-)-(2S)-2-(((4,6-Dimethylpyrimidin-2-yl)oxy)-3-Methoxy-3,3-Diphenylpropanoic Acid
CAS Nr	177036-94-1
Tshuag xwm txheej	Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons
Molecular Formula	C22H22N2O4
Molecular Luj	378.43 ib
Kev sib hloov tshwj xeeb [α]D20	+170.0° to +176.0° (C = 0.5, MeOH)
Melting Point	172.0 ~ 178.0 ℃ (txog.)
Solubility	Soluble heev hauv Methanol;Soluble hauv Ethanol, Acetone;Insoluble hauv dej
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Dawb los yog Off-White hmoov
Kev txheeb xyuas	HPLC;NMR;LC-MS
Yam khoom muaj feem
Tus kheej impurity	≤0.50%
Tag nrho cov impurities	<1.00%
Poob rau ziab	≤0.50%
Residue ntawm Ignition	≤ 0.20%
Hnyav Hlau	≤ 20ppm
Purity / Analysis Method	> 99.0% (HPLC)
Test Standard	Enterprise Standard
Kev siv	Pharmaceutical Intermediates

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo

Qhov zoo:

FAQ:

Daim ntawv thov:

(CAS: 177036-94-1) APIyog ib qho kev xaiv endothelin-A (ETA) receptor antagonist qhia rau kev kho qhov ncauj ntawm cov neeg mob nrog pulmonary arterial hypertension (PAH), txhawm rau txhim kho kev tawm dag zog lub cev thiab ncua sijhawm kho mob.PAH yog ib yam kab mob uas tsis tshua muaj ntawm cov hlab ntsws me me uas tshwm sim los ntawm vascular proliferation thiab kho dua tshiab, uas ua rau muaj kev nce ntxiv hauv cov hlab ntsws tsis zoo thiab cov hlab ntsha pulmonary siab, thiab thaum kawg, txoj cai ventricular tsis ua haujlwm thiab tuag ntxov ntxov.Cov tsos mob thaum ntxov ntawm PAH muaj xws li pib ua pa luv, nkees, palpitation, edema, thiab ua tsis taus pa.Endothelin-1 (ET-1), lub zog vasoconstrictor thiab cov leeg nqaij mitogen, yog ib qho tseem ceeb pab txhawb rau kev nrawm ntawm tus kab mob, thiab nws cov teebmeem tau kho los ntawm kev ua kom ETA thiab ETB receptors.Thaum Lub Rau Hli Ntuj xyoo 2007, FDA tau tso cai pom zoo (CAS: 177036-94-1) API rau kev kho PAH ib hnub ib zaug.