6,7-Bis(2-Methoxyethoxy)-4(3H)-Quinazolinone CAS 179688-29-0 Erlotinib Hydrochloride Intermediate Purity > 99.0% (HPLC)
Ua cov chaw tsim khoom thiab cov chaw muag khoom ntawm Erlotinib Hydrochloride Intermediates
Erlotinib Hydrochloride CAS 183319-69-9
3-Ethylaniline CAS 54060-30-9
6,7-Bis (2-Methoxyethoxy) -3H-Quinazolin-4-one CAS 179688-29-0
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| Tshuaj npe | 6,7-Bis (2-Methoxyethoxy)-3H-Quinazolin-4-ib |
| Synonyms | 6,7-Bis(2-Methoxyethoxy)-4(3H)-Quinazolinone;6,7-Bis(2-Methoxyethoxy)-3,4-Dihydroquinazolin-4-ib;6,7-Bis(2-Methoxyethoxy)-4-Hydroxyquinazoline;6,7-Bis (2-Methoxyethoxy) -4-Quinazolinol;PIB-380736 |
| impurity | Erlotinib Impurity A;Erlotinib Lactam impurity |
| CAS Nr | 179688-29-0 |
| CAT Number | TIAB SA 2685 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
| Molecular Formula | C14H18N2O5 |
| Molecular Luj | 294.31 Nws |
| Melting Point | 190.0 txog 194.0 ℃ |
| Qhov ntom | 1.26 ± 0.1g / cm3 |
| rhiab heev | Huab cua Sensitive |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Dawb los yog Off-White hmoov |
| Purity / Analysis Method | > 99.0% (HPLC) |
| Melting Point | 190.0 txog 194.0 ℃ |
| Poob rau ziab | <0.50% |
| Residue ntawm Ignition | <0.20% |
| Related Impurities los ntawm HPLC | |
| Tus kheej impurity | <0.50% |
| Tag nrho cov impurities | <1.00% |
| Hnyav Hlau | <10ppm |
| Infrared Spectrum | Raws li tus qauv |
| Test Standard | Enterprise Standard |
| Kev siv | Intermediate ntawm Erlotinib Hydrochloride (CAS: 183319-69-9) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
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15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Russia, Kauslim Teb, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
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Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
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Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
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6,7-Bis (2-Methoxyethoxy)-3H-Quinazolin-4-one (CAS: 179688-29-0) yog ib qho nruab nrab ntawm Erlotinib Hydrochloride (CAS: 183319-69-9).Erlotinib Hydrochlorate yog ib tug me me molecule tyrosine kinase inhibitor uas ua reversibly ntawm epidermal loj hlob yam receptors, ib tug hydrochloride ntawm erlotinib, ib tug molecular-targeted tshuaj.US Food and Drug Administration (FDA) tau pom zoo erlotinib (Tarceva) ua ke nrog gemcitabine raws li kev kho thawj zaug rau kev mob qog noj ntshav hauv zos thiab metastatic pancreatic.Nws yog siv los ua kev kho mob thib ob lossis thib peb rau kev kho mob hauv zos lossis kab mob metastatic uas tsis yog-me me ntawm lub ntsws cancer (NSCLC) thiab ua kev kho mob rau pancreatic cancer.Nws yog siv los ua tyrosine inhibitor rau kev kho NSCLC.Lub me me molecular compound Erlotinib Hydrochlorate yog tyrosine kinase receptor inhibitor uas inhibits kev loj hlob ntawm cov qog hlwb los ntawm inhibiting phosphorylation, khi rau intracellular catalytic domain ntawm tyrosine kinase nyob rau hauv kev sib tw nrog ATP, yog li thaiv downstream signal transduction thiab inhibiting kev ua ntawm cov qog cell ligand nyob ntawm seb. HER-1/EGFR.
