Lapatinib Intermediate CAS 231278-84-5 Purity > 98.0% (HPLC)

Lus piav qhia luv luv:

5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde

CAS: 231278-84-5 Nr

Purity:> 98.0% (HPLC)

Cov tsos mob: daj ntseg daj rau daj hmoov hmoov

API API (CAS 388082-77-7)

Hu rau: Dr. Alvin Huang

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E-Mail: alvin@ruifuchem.com

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Product Detail

Yam khoom

Khoom cim npe

Lapatinib Intermediates:

Lapatinib Base	CAS: 231277-92-2 Nr
Lapatinib Ditosylate Monohydrate	CAS Nr .: 388082-78-8
Sodium Methanesulfinate	CAS 20277-69-4 Nr
3-Chloro-4-(3-Fluorobenzyloxy) aniline	CAS Nr .: 202197-26-0
2-Aminoethyl Methyl Sulfone Hydrochloride	CAS Nr .: 104458-24-4
4-Chloro-6-Iodoquinazoline	CAS Nr .: 98556-31-1
6-Iodo-4-Hydroxyquinazoline	CAS Nr .: 16064-08-7
5-Formyl-2-Furanboronic Acid	CAS Nr .: 27329-70-0
5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde	CAS Nr .: 231278-84-5

Chemical Properties:

Tshuaj npe	5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde
Synonyms	Lapatinib Intermediate 3;5-[4-[[3-Chloro-4-[(3-Fluorophenyl)methoxy]phenyl]amino]-6-Quinazolinyl]-2-Furancarboxaldehyde;5-[4-((3-Chloro-4-((3-Fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-Furaldehyde
CAS Nr	231278-84-5
Tshuag xwm txheej	Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons
Molecular Formula	C26H17ClFN3O3
Molecular Luj	473.90 ib
Melting Point	225.0 txog 235.0 ℃
Qhov ntom	1.407 ± 0.06 g / cm3
Refractive Index	1.694 ib
COA & MSDS	Muaj
Keeb kwm	Shanghai, Suav
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Pale Yellow to Yellow Solid Powder
Purity / Analysis Method	> 98.0% (HPLC)
Melting Point	225.0 ~ 235.0 ℃
Poob rau ziab	<1.00%
Residue ntawm Ignition	<0.50%
Tag nrho cov impurities	<2.00%
Heavy Metals (raws li Pb)	<20 ppm
Test Standard	Enterprise Standard
Kev siv	API API (CAS 388082-77-7)

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo

Qhov zoo:

FAQ:

231278-84-5 - Daim ntawv thov:

5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde (CAS: 231278-84-5) yog ib qho nruab nrab ntawm API (CAS 388082-77-7) ).(CAS 388082-77-7) yog ib qho tshuaj tsom rau mob qog noj ntshav tsim los ntawm British GlaxoSmithKline Co. Nws yog ib qho tyrosine kinase inhibitor uas tuaj yeem cuam tshuam cov tyrosine kinase kev ua ntawm tib neeg epidermal kev loj hlob receptors 1 thiab 2 (ErbB1, ErbB2).Nws tuaj yeem ua haujlwm tshwj xeeb hauv ntau txoj hauv kev, kom ntseeg tau tias cov qog nqaij hlav cancer mis tsis tuaj yeem txais cov cim kev loj hlob.Nws inhibits intracellular EGFR (ErbB-1) thiab HER2 (ErbB-2) ATP chaw, tiv thaiv qog cell phosphorylation thiab ua kom muaj zog, thaiv cov kev cai qis los ntawm homogeneity thiab heterogeneity ntawm EGFR (ErbB-1) thiab HER2 (ErbB-1) dimerization.