CAS 242478-38-2 Purity ≥99.5% (HPLC) API
Commercial Supply Related Intermediates:
CAS: 242478-38-2 Nr
(R)-(-)-3-Quinuclidinol CAS: 25333-42-0
(S)-(+)-3-Quinuclidinol CAS: 34583-34-1
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
Tom ntej: 1-Phenyl-1,2,3,4-Tetrahydro-Isoquinoline CAS: 22990-19-8
(S)-1-Phenyl-1,2,3,4-Tetrahydroisoquinoline CAS: 118864-75-8
Synonyms | Vesicare;1-Azabicyclo[2.2.2]octan-8-yl (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate butanedioic acid |
CAS Nr | 242478-38-2 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C23H26N2O2 · C4H6O4 |
Molecular Luj | 480.56 ib |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb los yog Yuav luag Dawb Crystalline Hmoov |
Kev txheeb xyuas | Los ntawm IR;Los ntawm HPLC |
Solubility | Dawb Soluble hauv Acetic Acid, Dej, Methanol |
Melting Point | 144.0 ~ 150.0 ℃ |
Specific Optical Rotation | +88.0º ~ +94.0ºº |
Poob rau ziab | ≤0.50% |
Residue ntawm Ignition | ≤0.10% |
3-Quinuclidinol | ≤ 0.20% |
Succinate Cov ntsiab lus | 23.5 ~ 25.5% |
Optical Isomer | |
Diastereoisomer RS | ≤ 0.15% |
Diastereoisomer SS | ≤ 0.15% |
Diastereoisomer RR | ≤ 0.20% |
Residual Solvents | |
Acetone | ≤5000ppm |
Dichloromethane | ≤600ppm |
Toulene | ≤890ppm |
Diisopropyl Ether | ≤ 500ppm |
Dimethyl Formamide | ≤880ppm |
Yam khoom muaj feem | |
Ib qho Impurity | ≤0.10% |
Tag nrho cov impurities | ≤0.50% |
Hnyav Hlau | ≤ 20ppm |
Purity / Analysis Method | ≥99.5% (HPLC ntawm qhuav hauv paus) |
Test Standard | Enterprise Standard |
Kev siv | API;Overactive zais zis |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
API CAS: 242478-38-2 Nr.yog ib qho tshuaj antimuscarinic uas yog siv los kho lub zais zis ntau dhau ua rau cov tsos mob ntawm zaus, ceev, lossis incontinence.Nwsyog M3 muscarinic receptor antagonist uas tau tsim thiab tsim tawm rau kev kho mob ntawm cov zais zis ntau dhau (pollakiuria) hauv Tebchaws Europe.M3 receptors tau cuam tshuam rau hauv neurally evoked smooth nqaij contractions ntawm lub zais zis, thiab M2 receptors kuj tau xav tias ua si lub luag hauj lwm vim lawv dominance nyob rau hauv lub detrusor nqaij.Nws yog siv rau urological tshuaj.NwsNws yog ib qho urinary antispasmodic ntawm chav kawm antimuscarinic.