CAS 361440-67-7 Purity > 98.5% (HPLC) Hoobkas
Ruifu Chemical Supply Related Intermediates
CAS Nr .: 361442-04-8
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Tom ntej: 1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo [3.1.0]hexane-2-Carboxylic Acid Tert-Butyl Ester CAS 361440-67-7
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Tshuaj npe | (1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester |
Synonyms | N-Boc-L-cis-4,5-Methanoprolineamide;N-Boc-cis-4,5-Methano-L-Prolinamide;Tom ntej: tert-Butyl (1S,3S,5S)-3-Carbamoyl-2-Azabicyclo[3.1.0] hexane-2-Carboxylate |
CAS Nr | 361440-67-7 |
CAT Number | RF-PI 1990 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C11H18N2O3 |
Molecular Luj | 226.27 Nws |
Boiling Point | 388.9 ± 21.0 ℃ |
Qhov ntom | 1.228 ib |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb hmoov |
Purity / Analysis Method | > 98.5% (HPLC) |
Poob rau ziab | <0.50% |
Residue ntawm Ignition | <0.20% |
Tus kheej impurities | <1.00% |
Tag nrho cov impurities | <1.50% |
Test Standard | Enterprise Standard |
Kev siv | API API (CAS: 361442-04-8) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester (CAS: 361440-67-7) yog ib qho nruab nrab ntawm API (CAS: 361442) -04-8).(CAS: 361442-04-8) yog qhov ncauj hypoglycemic (cov tshuaj tiv thaiv kab mob ntshav qab zib) ntawm dipeptidyl peptidase-4 (DPP-4) inhibitor chav kawm ntawm cov tshuaj.Kev loj hlob thaum ntxov tsuas yog los ntawm Bristol-Myers Squibb;nyob rau hauv 2007 AstraZeneca koom nrog Bristol-Myers Squibb los koom ua ke tsim qhov kawg compound thiab koom tes ntawm kev lag luam ntawm cov tshuaj.Thaum Lub Rau Hli 2008, nws tau tshaj tawm tias Onglyza yuav yog lub npe lag luam raws li yuav tsum tau ua lag luam.API (CAS: 361442-04-8) yog siv los ua monotherapy lossis ua ke nrog lwm cov tshuaj rau kev kho mob ntshav qab zib hom 2.Nws yog absorbed sai sai tom qab kev tswj qhov ncauj thiab muaj ib tug pharmacokinetic profile sib xws nrog ib zaug ib hnub twg.Nws ua lub luag haujlwm los ntawm inhibiting GLP-l degradation.GLP-I yog cov tshuaj hormones tsim nyob rau hauv txoj hnyuv tom qab noj mov.