4,4′-Bis (2-Bromoacetyl)biphenyl CAS 4072-67-7 Daclatasvir Dihydrochloride Intermediate Purity > 98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom ntawm 4,4'-Bis (2-Bromoacetyl) biphenyl (CAS: 4072-67-7) nrog cov khoom zoo.Ruifu Chemical tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, kev pabcuam zoo heev, me me thiab ntau ntau muaj.Yuav 4,4'-Bis (2-Bromoacetyl)biphenyl,Please contact: alvin@ruifuchem.com
| Tshuaj npe | 4,4'-Bis (2-Bromoacetyl)biphenyl |
| Synonyms | 4,4'-Bis (Bromoacetyl)biphenyl;1,1'-[1,1'-Biphenyl]-4,4'-diylbis[2-Bromoethan-1-ib];Daclatasvir impurity 7 |
| Tshuag xwm txheej | Hauv Tshuag, Kev Lag Luam Ntau Lawm |
| CAS Nr | 4072-67-7 ib |
| Molecular Formula | C16H12Br2O2 |
| Molecular Luj | 396,07 g / mol |
| Melting Point | 226.0 ~ 227.0 ℃ |
| Qhov ntom | 1.622 ± 0.06 g / cm3 |
| COA & MSDS | Muaj |
| Keeb kwm | Shanghai, Suav |
| Qeb | Intermediate ntawm Daclatasvir Dihydrochloride (CAS: 1009119-65-6) |
| Hom | Ruifu Tshuaj |
| Cov khoom | Specifications | Cov txiaj ntsig |
| Qhov tshwm sim | Khoom | Khoom |
| Purity / Analysis Method | > 98.0% (HPLC) | 98.5% |
| Infrared Spectrum | Raws li tus qauv | Ua raws |
| 1 H NMR Spectrum | Raws li tus qauv | Ua raws |
| Xaus | Cov khoom tau raug kuaj thiab ua raws li cov lus qhia tshwj xeeb | |
| Daim ntawv thov | Intermediate ntawm Daclatasvir Dihydrochloride (CAS: 1009119-65-6) | |
Pob:Fluorinated Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, lossis raws li cov neeg siv khoom xav tau.
Cia txias:Khaws lub thawv kaw kom nruj thiab khaws cia rau hauv qhov chaw txias, qhuav thiab zoo-ventilated warehouse kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Shipping:Xa mus thoob ntiaj teb los ntawm huab cua, los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
4,4'-Bis (2-Bromoacetyl)biphenyl (CAS: 4072-67-7) yog ib qho nruab nrab ntawm Daclatasvir Dihydrochloride (CAS: 1009119-65-6).
Daclatasvir Dihydrochloride (Daklinza) yog ib qho inhibitor ntawm kab mob siab C (HCV) NS5A uas muaj txiaj ntsig zoo hauv kev kho mob ntawm genotype 3 chronic hepatitis C.
Thaum Lub Xya Hli 24, 2015, FDA tau pom zoo siv tshuaj kho kab mob siab C (Bristol-Myers Squibb) rau kev lag luam.
Txoj kev pom zoo los ntawm FDA ntawm Daklinza (Bristol-Myers Squibb) tau dhau los ua qhov sib tw thiab tig.Nws tau raug tso tseg ib zaug los ntawm FDA, tab sis thaum kawg tau pom zoo nyob rau nruab nrab-2015.FDA pom zoo ua ke ntawm Daklinza thiab Sofosbuvir rau kev kho mob siab C gene type 3 cov neeg mob.
Qhov tseeb, thaum ntxov ua ntej FDA pom zoo, Daklinza tau pom zoo rau kev lag luam hauv Nyiv, European Union thiab Kaus Lim Qab Teb thiab lwm lub tebchaws.Xyoo 2014, Nyiv kev noj qab haus huv sector tau pom zoo daim ntawv thov ntawm Daklinza thiab Asunaprevir (Sunvepra) rau kev kho mob ntawm genotype 1.Lub European Union kuj tau pom zoo Daclatasvir rau kev siv nrog rau lwm yam tshuaj nyob rau hauv kev kho mob ntawm HCV genotypes 1, 2, 3 thiab 4 nyob rau hauv 2014. Daclatasvir yog thawj NS5A complex inhibitor pom zoo los ntawm European Union (EU).Thaum siv ua ke nrog lwm cov tshuaj, piv nrog kev kho mob sib xyaw ua ke ntawm interferon thiab ribavirin uas siv sijhawm 48 lub lis piam, nws muaj sijhawm luv luv ntawm kev kho mob (12 lub lis piam lossis 24 lub lis piam).
Daclathavir monotherapy tsis pom zoo, cov txheej txheem tseem ceeb tam sim no yog kev sib xyaw ua ke ntawm Dacastavir + Sofosbuvir, uas yog tus cwj pwm los ntawm kev ua tau zoo, SVR siab dua, cov kev mob me me thiab kev kho mob luv luv dua li lwm cov kev xaiv.
