Apixaban Intermediate CAS 545445-44-1 Purity > 98.0% (HPLC)
Shanghai Ruifu Tshuaj Co., Ltd. -44-1) nrog cov khoom zoo, nruab nrab ntawm Apixaban (CAS: 503612-47-3).Ruifu Chemical tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, kev pabcuam zoo heev, me me thiab ntau ntau muaj.Yuav Apixaban Intermediates,Please contact: alvin@ruifuchem.com
| Tshuaj npe | 3-Morpholino-1-(4-(2-Oxopiperidin-1-yl)phenyl)-5,6-Dihydropyridin-2(1H)-ib |
| Synonyms | Apixaban Intermediate 1;5,6-Dihydro-3-(4-Morpholinyl)-1-[4-(2-Oxo-1-Piperidinyl)phenyl]-2(1H)-Pyridinone;5-Morpholin-4-yl-1-[4-(2-Oxopiperidin-1-yl)phenyl]-2,3-Dihydropyridin-6-ib;Apixaban Impurity A |
| Tshuag xwm txheej | Hauv Tshuag, Kev Lag Luam Ntau Lawm |
| CAS Nr | 545445-44-1 |
| Molecular Formula | C20H25N3O3 |
| Molecular Luj | 355.43 g / mol |
| Melting Point | > 199 ℃ (txog.) |
| Qhov ntom | 1.267 g / ml |
| COA & MSDS | Muaj |
| Keeb kwm | Shanghai, Suav |
| Qeb | Apixaban (CAS: 503612-47-3) |
| Hom | Ruifu Tshuaj |
| Cov khoom | Specifications | Cov txiaj ntsig |
| Qhov tshwm sim | Lub teeb daj hmoov | Lub teeb daj hmoov |
| Poob rau ziab | <0.50% | 0.16% |
| Residue ntawm Ignition | <0.20% | 0.07% |
| Purity / Analysis Method | > 98.0% (HPLC cheeb tsam) | 99.12% |
| Txhua tus neeg impurity | <0.50% | <0.50% |
| Tag nrho cov impurities | <2.00% | 0.88% |
| 1 H NMR Spectrum | Raws li tus qauv | Ua raws |
| LC-MS rau Kev Taw Qhia | Ua raws | Ua raws |
| Xaus | Cov khoom tau raug kuaj thiab ua raws li cov lus qhia tshwj xeeb | |
| Daim ntawv thov | Apixaban (CAS: 503612-47-3) | |
Pob:Fluorinated Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, lossis raws li cov neeg siv khoom xav tau.
Cia txias:Khaws lub thawv kaw kom nruj thiab khaws cia rau hauv qhov chaw txias, qhuav thiab zoo-ventilated warehouse kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Shipping:Xa mus thoob ntiaj teb los ntawm huab cua, los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
3-Morpholino-1-(4-(2-Oxopiperidin-1-yl)phenyl)-5,6-Dihydropyridin-2(1H)-ib (CAS: 545445-44-1) yog ib qho nruab nrab ntawm Apixaban (CAS: 503612-47-3).
Apixaban yog ib hom tshiab ntawm qhov ncauj Xa factor inhibitor ua ke tsim los ntawm Bristol-Myers Squibb thiab Pfizer.Lub npe lag luam yog Eratol, uas yog hom tshiab ntawm qhov ncauj anticoagulant.Los ntawm inhibiting ib qho tseem ceeb coagulation factor Xa, Apixaban tuaj yeem tiv thaiv kev tsim cov thrombin thiab thrombosis.Thaum Lub Plaub Hlis 26, 2007, Bristol-Myers Squibb tau koom tes nrog Pfizer los tshaj tawm kev koom tes hauv kev tsim cov tshuaj tiv thaiv qhov ncauj tshiab Apixaban uas yog Bristol-Myers Squibb raws li kev hloov kho dua tshiab rau Warfarin.Nyob rau lub Tsib Hlis 2011, Apixaban yog thawj zaug pom zoo rau kev tiv thaiv ntawm venous thrombosis nyob rau hauv cov neeg laus cov neeg laus uas tau xaiv lub duav los yog lub hauv caug hloov pauv nyob rau hauv 27 EU lub teb chaws, Iceland thiab Norway.Thaum Lub Kaum Ib Hlis 20, 2012, European Commission tau pom zoo Ererto (Apixaban) rau kev tiv thaiv kev mob stroke thiab cov kab mob embolism hauv cov neeg laus uas tsis yog-valvular atrial fibrillation (NVAF) nrog rau ib lossis ntau qhov kev pheej hmoo.Tom qab ntawd, Canadian Food and Drug Administration, Nyiv, thiab US FDA tau pom zoo Ererto (Apixaban) rau kev tiv thaiv kab mob stroke thiab cov kab mob embolism hauv cov neeg laus uas tsis yog-valvular atrial fibrillation (NVAF) nrog ib lossis ntau qhov kev pheej hmoo.Thaum Lub Plaub Hlis 12, 2013, cov tshuaj tiv thaiv kab mob tshiab Eloto (ELIQUIS) (Apixaban) sib koom ua ke tsim los ntawm Bristol-Myers Squibb thiab Pfizer tau tshaj tawm tias muaj npe nyob hauv Suav teb.
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