5-Amino-3-(Trifluoromethyl)picolinonitrile CAS 573762-62-6 Apalutamide Intermediate Purity > 98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom ntawm 5-Amino-3-(Trifluoromethyl) picolinonitrile (CAS: 573762-62-6) nrog cov khoom zoo, nruab nrab ntawm Apalutamide (CAS: 956104-40-8).Ruifu Chemical tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, kev pabcuam zoo heev, me me thiab ntau ntau muaj.Yuav Apalutamide Intermediates,Please contact: alvin@ruifuchem.com
| Tshuaj npe | 5-Amino-3-(Trifluoromethyl) picolinonitrile |
| Synonyms | 5-Amino-3-(Trifluoromethyl)pyridine-2-Carbonitrile;5-Amino-3-(Trifluoromethyl) 2-Cyanopyridine;5-Amino-2-Cyano-3-(Trifluoromethyl) pyridine;Apalutamide impurity 10 |
| Tshuag xwm txheej | Hauv Tshuag, Kev Lag Luam Ntau Lawm |
| CAS Nr | 573762-62-6 |
| Molecular Formula | C7H4F3N3 |
| Molecular Luj | 187.12 g / mol |
| Qhov ntom | 1.45 ± 0.10g / cm3 |
| COA & MSDS | Muaj |
| Keeb kwm | Shanghai, Suav |
| Hazard Class | 6.1 |
| Packing Group | Ⅲ |
| Qeb | Intermediate ntawm Apalutamide (CAS: 956104-40-8) |
| Hom | Ruifu Tshuaj |
| Cov khoom | Kev soj ntsuam Standards | Cov txiaj ntsig |
| Qhov tshwm sim | Lub teeb daj rau daj khoom | Ua raws |
| Dej los ntawm Karl Fischer | <0.50% | 0.35% |
| Purity / Analysis Method | > 98.0% (HPLC) | 99.03% |
| Infrared Spectrum | Raws li tus qauv | Ua raws |
| 1 H NMR Spectrum | Raws li tus qauv | Ua raws |
| Xaus | Cov khoom tau raug kuaj thiab ua raws li cov lus qhia tshwj xeeb | |
| Daim ntawv thov | Intermediate ntawm Apalutamide (CAS: 956104-40-8) | |
Pob:Fluorinated Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, lossis raws li cov neeg siv khoom xav tau.
Cia txias:Khaws lub thawv kaw kom nruj thiab khaws cia rau hauv qhov chaw txias, qhuav thiab zoo-ventilated warehouse kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Shipping:Xa mus thoob ntiaj teb los ntawm huab cua, los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
5-Amino-3-(Trifluoromethyl) picolinonitrile (CAS: 573762-62-6), yog pyridine heterocyclic organic compound, uas tuaj yeem siv los ua cov tshuaj intermediates.5-Amino-3-(Trifluoromethyl) picolinonitrile yog ib qho nruab nrab ntawm Apalutamide (CAS: 956104-40-8).Apalutamide yog ib tug thib ob tiam antiandrogen siv nyob rau hauv kev kho mob ntawm prostate cancer.Nws yog lub zog antagonist ntawm androgen receptor nrog IC50 tus nqi ntawm 16 nM.Binds androgen receptors, yog li inhibiting nuclear translocation, DNA binding thiab transcriptional activation.Apalutamide muaj kev siv tshuaj kho mob hauv cov tsis-metastatic, castration-resistant prostate cancer.
Apalutamide yog siv los kho qee yam ntawm castration-resistant prostate cancer lossis prostate cancer uas tsis kis mus rau lwm qhov ntawm lub cev, tab sis tsis tau pab los ntawm lwm yam kev kho mob.Apalutamide yog nyob rau hauv ib chav kawm ntawm cov tshuaj hu ua androgen receptor inhibitors.Nws ua haujlwm los ntawm kev thaiv cov teebmeem ntawm androgen kom tsis txhob muaj kev loj hlob thiab kis ntawm cov qog nqaij hlav cancer.Thaum lub Cuaj Hlis 17, 2019, Lub Chaw Tswj Xyuas Khoom Noj thiab Tshuaj tau pom zoo Apalutamide (ERLEADA, Janssen Biotech, Inc) rau cov neeg mob uas muaj kab mob metastatic castration-sensitive prostate cancer (mCSPC).Apalutamide tau pib pom zoo xyoo 2018 rau cov neeg mob uas tsis yog-metastatic castration-resistant prostate cancer.
