Trelagliptin Succinate Intermediate CAS 865759-24-6 Purity > 98.0% (HPLC)

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Trelagliptin Succinate Intermediate-int D

CAS: 865759-24-6 Nr

Purity:> 98.0% (HPLC)

Cov tsos mob: Tawm-dawb mus rau lub teeb daj Crystal

Intermediate ntawm Trelagliptin Succinate (CAS: 1029877-94-8) rau kev kho mob ntshav qab zib hom 2

Hu rau: Dr. Alvin Huang

Txawb/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Product Detail

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Nqe lus piav qhia:

Kev muag khoom muag Trelagliptin Succinate Related Intermediates:
6-Chloro-3-Methyluracil CAS 4318-56-3
Tom ntej: 2-Cyano-5-Flurobenzyl Bromide CAS 421552-12-7
(R)-(-)-3-Aminopiperidine Dihydrochloride CAS 334618-23-4
Trelagliptin Succinate Intermediate-int D CAS 865759-24-6
Trelagliptin Succinate CAS 1029877-94-8
Please contact: alvin@ruifuchem.com

Chemical Properties:

Tshuaj npe	Trelagliptin Succinate Intermediate-int D
Synonyms	2-((6-Chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile;2-[(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-4-fluorobenzonitrile
impurity	Trelagliptin Impurity 17
Tshuag xwm txheej	Hauv Tshuag, Kev Lag Luam Loj
CAS Nr	865759-24-6
Molecular Formula	C13H9ClFN3O2
Molecular Luj	293.68 g / mol
Qhov ntom	1.49 ± 0.10g / cm3
Cia Temp.	Txias & qhuav qhov chaw
COA & MSDS	Muaj
Hom	Ruifu Tshuaj

Specifications:

Cov khoom	Kev soj ntsuam Standards	Cov txiaj ntsig
Qhov tshwm sim	Off-White mus rau lub teeb daj Crystal	Ua raws
Kev txheeb xyuas
HPLC	Lub sijhawm khaws cia ntawm cov qauv ntsuas qhov siab tshaj plaws ua raws li tus qauv siv	Ua raws
IR - Infrared Spectrum	IR Absorption spectra ntawm cov qauv thiab cov qauv yog concordant	Ua raws
Kev tshuaj xyuas
Poob rau ziab	<0.50%	0.3%
Tag nrho cov impurities	<2.00%	Ua raws
Purity / Analysis Method	> 98.0% (HPLC)	99.1%
Xaus	Cov khoom tau raug kuaj & ua raws li cov specifications

Pob / Cia /Shipping:

Pob:Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim kaw ntawm qhov txias thiab qhuav thiab zoo-ventilated warehouse kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.Zam lub teeb;Airtight.
Shipping:Xa mus thoob ntiaj teb los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.

Qhov zoo:

Muaj peev xwm txaus: Muaj cov chaw txaus thiab cov kws tshaj lij

Kev Pabcuam Kev Ua Haujlwm: Ib qho kev pabcuam kev yuav khoom

Pob OEM: Kev cai pob thiab daim ntawv lo muaj

Kev xa khoom sai: Yog tias nyob hauv Tshuag, peb hnub xa khoom lav

Stable Supply: Khaws cov khoom tsim nyog

Kev them nyiaj yug Technical: Technology tov muaj

Kev Pabcuam Synthesis: Ntau yam ntawm grams mus rau kilos

High Quality: Tsim kom muaj kev ruaj ntseg zoo

FAQ:

Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.

Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.

Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.

ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.

Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.

Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.

MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.

Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.

Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.

Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.

Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.

Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.

Daim ntawv thov:

2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile (CAS: 865759-24-6) Intermediate ntawm Trelagliptin Succinate (CAS: 1029877-94-8).Trelagliptin Succinate, tsim los ntawm Takeda, Nyiv, pib thaum Lub Peb Hlis 2015, raws li kev lag luam npe Zafatek, yog siv los kho hom 2 mob ntshav qab zib.Trelagliptin yog ib qho ultra-ntev-acting dipeptidyl peptidase IV (DPP-4) inhibitor los ntawm kev xaiv thiab tsis tu ncua inhibiting DPP-4 los tswj cov ntshav qab zib.Trelagliptin yog thawj cov tshuaj hypoglycemic txhua lub lim tiam ntawm kev ua lag luam, thiab cov tshuaj zoo sib xws DPP-4 hauv khw yuav tsum tau noj ib hnub ib zaug.Zafatek cov tshuaj zoo yuav ua rau muaj kev kho mob yooj yim dua rau cov neeg mob ntshav qab zib.Nws xav tias yuav txhim kho qhov yooj yim thiab ua raws li cov neeg mob.Lub Peb Hlis 26, 2015, Japanese kws tshuaj loj Takeda tshaj tawm tias cov tshuaj mob ntshav qab zib tshiab Zafatek tau pom zoo los ntawm Nyiv Ministry of Health, Labor thiab welfare (MHLW) rau kev kho mob ntshav qab zib hom 2.Qhov kev pom zoo ua rau Zafatek dhau los ua thawj lub lim tiam ntawm qhov ncauj hypoglycemic tshuaj nyob rau hauv kev ua lag luam hauv ntiaj teb, thiab tseem sawv cev rau tus blockbuster poob los ntawm Takeda hauv khw muag ntshav qab zib.
Trelagliptin yog ib lub lim tiam ib zaug dipeptidyl peptidase IV (DPP-4) inhibitor uas tswj cov ntshav qab zib theem los ntawm kev xaiv thiab tsis tu ncua inhibiting DPP-4.DPP-4 yog ib qho enzyme uas tuaj yeem pib ua kom tsis muaj zog ntawm incretin (glucagon-zoo li peptide -1 (GLP-1) thiab glucose-dependent insulinotropic polypeptide (GIP)), uas ua lub luag haujlwm tseem ceeb hauv kev tswj cov ntshav qabzib.Inhibition ntawm DPP-4 tuaj yeem ua rau cov ntshav qab zib ntau ntxiv-nyob ntawm insulin secretion, yog li tswj cov ntshav qab zib.Kev xa tawm Trelagliptin NDA yog ua raws li kev ua tau zoo thiab kev nyab xeeb cov ntaub ntawv los ntawm ntau theem III kev sim tshuaj ntsuam xyuas hauv Nyiv cov neeg mob ntshav qab zib hom 2.Qhov kev ua tau zoo ntawm Trelagliptin tau raug lees paub hauv txhua qhov kev sim, thiab nws muaj kev nyab xeeb zoo thiab ua haujlwm ntev.Kev tswj hwm Trelagliptin ib zaug ib lub lim tiam tuaj yeem tswj cov ntshav qab zib kom zoo thiab xav tias yuav txhim kho cov neeg mob cov tshuaj ua raws cai.