CAS 928672-86-0 Purity ≥99.0% (HPLC) API
CAS Nr | 928672-86-0 |
CAT Number | RF-API 22 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms |
Molecular Formula | C24H27FO6S |
Molecular Luj | 462.53 ib |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb hmoov |
Kev txheeb xyuas | HPLC/NMR |
Solubility | Soluble heev hauv Methanol;Soluble hauv Ethanol, Acetonitrile;Me ntsis Soluble hauv dej |
Purity / Analysis Method | ≥99.0% (HPLC) |
Tus kheej impurity | ≤0.10% |
Tag nrho cov impurities | ≤0.50% |
Residual Solvents | |
Methanol | ≤3000ppm |
Ethanol | ≤5000ppm |
Cov tshuaj acetonitrile | ≤400ppm |
Dichloromethane | ≤600ppm |
Ethyl Acetate | ≤5000ppm |
THF | ≤720ppm |
Toluene | ≤890ppm |
Test Standard | Suav Pharmacopoeia (CP);Enterprise Standard |
Kev siv | Cov khoom xyaw tshuaj nquag (API);SGLT-2 inhibitors Hom 2 Ntshav Qab Zib |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo
Nws yog ib qho tshuaj ntawm cov chav kawm gliflozin lossis subtype 2 sodium-glucose thauj inhibitors (SGLT2) siv rau kev kho mob ntshav qab zib hom 2.Nws tau tsim los ntawm Mitsubishi Tanabe Pharma thiab tau ua lag luam raws li daim ntawv tso cai los ntawm Janssen, ib feem ntawm Johnson & Johnson.Nws yog lub luag haujlwm rau tsawg kawg 90% ntawm cov piam thaj reabsorption hauv lub raum.Thaiv cov khoom thauj no ua rau cov ntshav qabzib raug tshem tawm los ntawm cov zis.Thaum Lub Peb Hlis 2013, Nws tau dhau los ua thawj SGLT2 inhibitor kom pom zoo hauv Tebchaws Meskas.To hais txog qhov kom zoo dua, cov tshuaj no pab cov neeg mob kom txo cov ntshav qab zib yam tsis tas yuav nce qhov hnyav li ntev tau raws li kev noj qab haus huv, kev noj zaub mov kom zoo thiab ua haujlwm tsis tu ncua.Tsis tas li ntawd, Nws muaj kev cia siab dav vim nws qhov cuam tshuam loj rau kev tiv thaiv kev rog thiab ob peb cov xwm txheej hypoglycemic.