Caspofungin Acetate Cancidas CAS 179463-17-3 API Hoobkas High Purity
Chaw tsim tshuaj paus nrog High Purity thiab ruaj khov zoo
Lub npe tshuaj: Caspofungin Acetate
CAS: 179463-17-3 Nr
API High Quality, Commercial Production
| Tshuaj npe | Caspofungin Acetate |
| Synonyms | Cancidas;MK-0991 Acetate;L-743872 Acetate |
| CAS Nr | 179463-17-3 |
| CAT Number | RF-API 58 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms |
| Molecular Formula | C52H88N10O15 · 2C2H4O2 |
| Molecular Luj | 1213.42 Nws |
| Melting Point | > 197 ℃ |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Dawb los yog Yuav luag Dawb Hmoov |
| Identification IR | IR: Spectrum of Test qauv yuav tsum ua raws li Caspofungin Acetate Reference Standard |
| Kev txheeb xyuas HPLC | HPLC: Lub sijhawm khaws cia ntawm lub hauv paus ntsiab lus siab tshaj plaws tau txais los ntawm kev tshuaj ntsuam xyuas yuav tsum ua raws li qhov tau txais los ntawm cov qauv kev daws teeb meem, raws li kev sim hauv Assay |
| Clarity thiab Xim | Cov tshuaj yuav tsum yog ntshiab thiab tsis muaj xim |
| Kev sib hloov tshwj xeeb | -102.0° ~ -108.0° |
| pH | 5.0 ~ 7.0 |
| Dej | ≤ 10.0% |
| Yam khoom muaj feem I | (Ntawm Anhydrous thiab Acetic Acid Free Basis) |
| impurity A | ≤0.10% |
| Impurity B | ≤0.10% |
| Impurity D | ≤ 0.30% |
| Impurity E | ≤0.10% |
| Unspecified Impurity F | ≤0.10% |
| Unspecified impurity G | ≤0.10% |
| Pneumocandin B0 | ≤0.10% |
| Ib Unknown Impurity | ≤0.10% |
| Tag nrho cov impurities | ≤ 1.0% |
| Yam Khoom Muaj Cai II | ≤0.10% |
| Residual Solvents | |
| Ethyl Acetate | ≤5000ppm |
| Ethanol | ≤5000ppm |
| Methanol | ≤5000ppm |
| Cov tshuaj acetonitrile | ≤410ppm |
| Tetrahydrofuran | ≤720ppm |
| Cov ntsiab lus ntawm acetic acid | 9.0% ~ 11.0% (Xam ntawm Anhydrous Basis) |
| Ethylendiamine | ≤0.10% |
| Residue ntawm Ignition | ≤0.10% |
| Heavy Metals (raws li Pb) | ≤10ppm |
| Assay / Analysis Method | 97.0% ~ 102.0% (Rau Anhydrous thiab Solvent Free Basis) |
| Test Standard | Enterprise Standard |
| Kev siv | Active Pharmaceutical Ingredients (API) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
Caspofungin Acetate (CAS: 179463-17-3) yog lipopeptide antifungal tshuaj.Caspofungin acetate rau kev txhaj tshuaj yog Ameslikas pom zoo los ntawm FDA hauv Tebchaws Meskas, thiab EMEA hauv Tebchaws Europe, xyoo 2001. Caspofungin Acetate yog cov dej soluble, ruaj khov, aza-substituted semisynthetic derivative ntawm Pneumocandin B, fermentation khoom ntawm cov fungus Zalerion arboricola.Cov lipopeptide caspofungin, inhibits cov synthesis ntawm 1,3-beta-D-glucans tam sim no tsuas yog nyob rau hauv lub fungal cell phab ntsa, uas ua rau lub lysis ntawm pathogenic hlwb.Cov tshuaj yog fungicidal es tsis yog fungistatic, ib qho txawv feature ntawm cov tshuaj tiv thaiv kab mob.Caspofungin feem ntau ua haujlwm ntau dua li amphotericin B, flucytosine, fluconazole thiab itraconazole tawm tsam Candida hom.
