CDI CAS 530-62-1 N, N'-Carbonyldiimidazole Coupling Reagent Purity > 98.0% (T) Hoobkas
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom ntawm N, N'-Carbonyldiimidazole (CDI) (CAS: 530-62-1) nrog cov khoom zoo.Ruifu Chemical muab cov txheej txheem tiv thaiv reagents thiab coupling reagents.Ruifu tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, me me thiab ntau ntau muaj.Yuav CDI,Please contact: alvin@ruifuchem.com
Tshuaj npe | N, N'-Carbonyldiimidazole |
Synonyms | CDI;1,1'-Carbonyldiimidazole;1,1'-Carbonylbis-1H-Imidazole;Di-1H-imidazol-1-yl-methanone;1,1'-Carbonylbisimidazole;N, N'-Carbonylbis (Imidazole) |
Tshuag xwm txheej | Hauv Tshuag, Kev Tsim Khoom Loj |
CAS Nr | 530-62-1 : kuv |
Molecular Formula | C7H6N4O |
Molecular Luj | 162.15 g / mol |
Melting Point | 116.0 ~ 122.0 ℃ (lit.) |
Qhov ntom | 1.303 g / mL ntawm 25 ℃ |
Khaws hauv qab Inert Gas | Khaws hauv qab Inert Gas |
rhiab heev | Hygroscopic, Moisture Sensitive, Thaum tshav kub kub rhiab heev |
Dej Solubility | Insoluble hauv dej |
Solubility | Soluble hauv Dimethylformamide |
Cia Temp. | Qhov chaw txias & qhuav (2 ~ 8 ℃) |
COA & MSDS | Muaj |
Qeb | Coupling Reagents |
Hom | Ruifu Tshuaj |
Cov khoom | Kev soj ntsuam Standards | Cov txiaj ntsig |
Qhov tshwm sim | Dawb rau Off-White Crystalline Hmoov | Ua raws |
Melting Point | 116.0 txog 122.0 ℃ | 118.0 ~ 118.5 ℃ |
Poob rau ziab | <0.50% | 0.03% |
Purity / Analysis Method | > 99.0% (Titration) | 99.1% |
Solubility hauv DMF 50mg / ml | Ntshiab mus me ntsis Hazy | Ua raws |
Infrared Spectrum | Raws li tus qauv | Ua raws |
Xaus | Cov khoom tau raug kuaj & ua raws li cov lus qhia tshwj xeeb |
Pob:Lub raj mis, 25 kilogram hlau thoob (40 × 55) txhuas ntawv ci yaug cov nitrogen kom ntim, lossis raws li cov neeg siv khoom xav tau.
Cia txias:Hygroscopic, noo noo rhiab heev.Cov khoom no yuav tsum tau muab cia rau hauv qhov chaw txias, qhov cua, qhov chaw qhuav, kom deb ntawm qhov hluav taws kub, qhov chaw kub, qhov kub thiab txias, noo noo, dej, lub teeb, insolation.Thaum lub sij hawm kev thauj mus los, thov ua tib zoo ua tib zoo tiv thaiv lub pob los ntawm kev tawg.Khaws cov khoom no kaw kom zoo.
Shipping:Xa mus thoob ntiaj teb los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.
N, N'-Carbonyldiimidazole (CDI)
Cov qauv zoo
Kauj ruam 1 Qauv
Cov khoom no yog ib qho yooj yim rau decompose thaum raug cov dej noo, qhov chaw sampling yuav tsum nyob rau hauv qhov chaw txias thiab qhuav, sampling (nrog rau cov qauv hnyav).Cov khoom siv yuav tsum huv thiab qhuav thiab sai sai.
2. Khoom
Siv 5g qauv rau hauv lub raj mis tsis muaj xim, pob tshab, kaw nws, muab tso rau hauv lub teeb ntuj, thiab saib sai sai nrog qhov muag liab qab saib.
Kauj Ruam 3: Purity
Precision hnyav qauv 0.2g ~ 0.3g rau hauv lub raj mis conical.Ntxiv glacial acetic acid 35ml, ntxiv acetic anhydride 1ml, crystal violet qhia 2 tee.Qhov poob tau titrated nrog 0.1mol / L perchloric acid kom txog thaum cov ntshav ploj, thiab kuaj dawb tau ua.
Kev suav cov mis:
FX(V-V0) × 8.1075
Purity = ----------------------- × 100%
M × 1000
Qhov twg:
F: Perchloric acid titration tov concentration kho qhov tseem ceeb
V: Volume ntawm cov qauv titration
V0: ntim ntawm titration dawb paug
8.1075: Txhua 1ml ntawm titrant noj yog sib npaug rau 8.1075mg ntawm cov qauv
M: Loj ntawm cov qauv (g)
4. Melting point
3.1 Cov cuab yeej thiab cov khoom siv a) Melting point instrument
b) Capillary
3.2 Cov txheej txheem
khau raj, melting point ntsuas debugging, yuav tsum tau kuaj.Ceev ceev ntim cov qauv nrog capillary (vim cov qauv thiab yooj yim rau decompose), nias
Melting point ntsuas kev ua haujlwm txoj kev ua haujlwm.
5. Cia: Khaws rau hauv qhov chaw txias thiab qhuav kom deb ntawm lub teeb
6. Reinspection lub sij hawm: ib xyoos
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
Risk Codes
R22 - Ua phem yog tias nqos
R34 - Ua rau kub hnyiab
R36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij.
R40 - Cov pov thawj txwv ntawm cov nyhuv carcinogenic
R36/38 - Kab mob rau qhov muag thiab tawv nqaij.
Kev nyab xeeb piav qhia
S26 - Nyob rau hauv rooj plaub ntawm qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
S36/37/39 - Hnav cov khaub ncaws tiv thaiv, hnab looj tes thiab tiv thaiv qhov muag / ntsej muag.
S45 - Thaum muaj xwm txheej lossis yog tias koj tsis xis nyob, nrhiav kev kho mob tam sim ntawd (qhia daim ntawv lo thaum twg los tau.)
S37/39 - Hnav cov hnab looj tes tsim nyog thiab tiv thaiv qhov muag / ntsej muag
S27 - Tshem tawm tag nrho cov khaub ncaws tsis huv tam sim ntawd.
S36/37 - Hnav cov khaub ncaws tiv thaiv thiab hnab looj tes tsim nyog.
UN IDs UN 3263 8/PG 2
WGK Germany 2
FLUKA BRAND F CODE 10-21
TSCA T
HS Code 2933290090
Hazard Note Harmful / Corrosive / Moisture Sensitive
Hazard Chav Kawm 8
Packing Group III
Toxicity LD50 qhov ncauj hauv Luav: 1071 mg / kg
N, N'-Carbonyldiimidazole (CDI) (CAS: 530-62-1), peptide coupling reagent, siv nyob rau hauv cov synthesis ntawm peptides.CDI yog peptide coupling reagent, nws yog siv nyob rau hauv lub synthesis ntawm peptides.Reacts nrog carboxylic acids los tsim acyl imidazoles;Tom qab cov tshuaj tiv thaiv nrog amines tsim amides mus smoothly.
Ib qho tseem ceeb condensation tus neeg sawv cev los ua ke nucleoside triphosphates, peptide-triphosphate thiab triphosphate;Ib qho tseem ceeb nruab nrab los ua ke acylimidazole.
Raws li tus neeg sawv cev condensation rau kev sib txuas ntawm triphosphonucleosides, peptides thiab esters;Thiab yog ib qho tseem ceeb nruab nrab ntawm cov synthesis ntawm acyl imidazole thiab pyridoxamide, biochemical hluavtaws pab pawg tiv thaiv thiab protein peptide saw txuas.
Peptide coupling reagent CDI ua raws li kev sib txuas reagent thiab siv rau kev sib txuas ntawm cov amino acids txhawm rau npaj peptide hauv cov organic synthesis.Nws kuj tseem siv rau hauv kev npaj ntawm beta-keto sulfones, sulfoxides thiab beta-enamino acid derivatives.Nws yog siv los hloov cov cawv thiab amines rau hauv carbamates, esters, thiab ureas.Nws yog koom nrog hauv kev npaj ntawm formylized imidazole los ntawm cov tshuaj tiv thaiv nrog formic acid.Tsis tas li ntawd, nws yog siv nyob rau hauv synthesis ntawm dipolar polyamides tebchaw.Ntxiv rau qhov no, nws raug suav tias yog qhov sib npaug ntawm phosgene thiab siv los npaj asymmetric bis alkyl carbonate.
CDI yog ib tug derivative ntawm imidazole, thiab nws cov qauv imidazole muaj ib tug kaw loj P daim ntawv cog lus, thiab muaj ib leeg ib khub ntawm electrons nyob rau hauv lub sp2 orbital qhov twg ib tug nitrogen atom tsis bonded.Cov no txiav txim siab tias CDI muaj cov tshuaj tiv thaiv tshuaj muaj zog, tuaj yeem hnov mob nrog ammonia, cawv, kua qaub thiab lwm pab pawg ua haujlwm, thiab ua kom muaj ntau lub tebchaw uas nyuaj kom tau txais los ntawm kev siv tshuaj lom neeg.Nws yog dav siv los ua ib qho enzyme thiab protein binder, ib qho nruab nrab hauv kev sib xyaw ntawm cov tshuaj tua kab mob, tshwj xeeb tshaj yog ua tus neeg sawv cev rau cov khoom sib txuas ntawm polypeptide.
CDI yog xoom ntev crosslinking reagent siv rau ob peb lub ntsiab amines rau carboxyllic acid ua haujlwm pab pawg.CDI reacts nrog cov carboxylate ion (COO-) ntawm cov proteins los yog lwm cov organic tebchaw, tsim ib tug reactive intermediate uas yog tom qab reacted nrog ib tug amino pawg (-NH2).Cov reagent no tuaj yeem siv rau ob peb cov proteins, thiab feem ntau yog siv rau hauv cov protein immobilization rau cov khoom txhawb nqa lossis daim nyias nyias.Yooj yim, CDI tuaj yeem siv rau hauv ob qho tib si aqueous thiab organic solvent systems.
Siv ua tshuaj tua kab thiab tshuaj nruab nrab.